ID G1K9W0_ANOCA Unreviewed; 1199 AA.
AC G1K9W0;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 3.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Ankyrin repeat and sterile alpha motif domain containing 1A {ECO:0000313|Ensembl:ENSACAP00000001718.4};
GN Name=ANKS1A {ECO:0000313|Ensembl:ENSACAP00000001718.4};
OS Anolis carolinensis (Green anole) (American chameleon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Dactyloidae; Anolis.
OX NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000001718.4, ECO:0000313|Proteomes:UP000001646};
RN [1] {ECO:0000313|Ensembl:ENSACAP00000001718.4, ECO:0000313|Proteomes:UP000001646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000001718.4,
RC ECO:0000313|Proteomes:UP000001646};
RG The Genome Sequencing Platform;
RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACAP00000001718.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; G1K9W0; -.
DR STRING; 28377.ENSACAP00000001718; -.
DR Ensembl; ENSACAT00000001758.4; ENSACAP00000001718.4; ENSACAG00000001592.4.
DR eggNOG; KOG0507; Eukaryota.
DR GeneTree; ENSGT00940000155806; -.
DR HOGENOM; CLU_010379_0_0_1; -.
DR TreeFam; TF320582; -.
DR Proteomes; UP000001646; Chromosome 4.
DR Bgee; ENSACAG00000001592; Expressed in hemipenis and 13 other cell types or tissues.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0046875; F:ephrin receptor binding; IBA:GO_Central.
DR GO; GO:0048013; P:ephrin receptor signaling pathway; IBA:GO_Central.
DR CDD; cd01274; PTB_Anks; 1.
DR CDD; cd09499; SAM_AIDA1AB-like_repeat1; 1.
DR CDD; cd09500; SAM_AIDA1AB-like_repeat2; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 2.
DR InterPro; IPR033635; ANKS1/Caskin.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR006020; PTB/PI_dom.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR041880; SAM_ANKS1_repeat1.
DR InterPro; IPR041882; SAM_ANKS1_repeat2.
DR PANTHER; PTHR24174:SF4; ANKYRIN REPEAT AND SAM DOMAIN-CONTAINING PROTEIN 1A; 1.
DR PANTHER; PTHR24174; ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF12796; Ank_2; 3.
DR Pfam; PF00640; PID; 1.
DR Pfam; PF00536; SAM_1; 2.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 6.
DR SMART; SM00462; PTB; 1.
DR SMART; SM00454; SAM; 2.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 2.
DR PROSITE; PS50297; ANK_REP_REGION; 5.
DR PROSITE; PS50088; ANK_REPEAT; 6.
DR PROSITE; PS01179; PID; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 2.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Reference proteome {ECO:0000313|Proteomes:UP000001646};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 79..111
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 112..144
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 148..180
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 181..213
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 214..246
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 246..278
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 734..797
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 804..863
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 974..1106
FT /note="PID"
FT /evidence="ECO:0000259|PROSITE:PS01179"
FT REGION 33..56
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 303..331
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 369..515
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 620..691
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1105..1133
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1162..1199
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 317..331
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 379..420
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 431..463
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 481..514
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 659..691
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1199 AA; 130903 MW; AAC8D346E84F4559 CRC64;
MGKEQELLEA SRTGNLPAVE KLLSGKRLSS GFGSGGGGSG GGGGSSGGGG GGGSGGGGHP
LSSLLSIWRG PNVNCVDSTG YTPLHHAALN GHKDVVEVLL RNDALTNVAD CKGCYPLHLA
AWKGDAEIVK LLIHQGPSHT KVNEQNNDNE TALHCAAQYG HTEVVKVLLE ELTDPTMRNN
KFETPLDLAA LYGRLEVVKM LLNAHPNLLS CNTKKHTPLH LAARNGHKAV VHVLLDAGMD
NNYQTEKGSA LHEAALFGKT DVVQILLAAG IDVNIKDNRG LTALEIVREL PSQKSQQIAS
LIEESTTGKK ANKVEEKSTS GSSTSTETLV QLSQGNVEKA VTELIIDFDG KPEECPYEVL
YNATSCHSLD SLASGRSSDR DSVNREAEMT NVRVRPRERP PPPAKPPPDE EEEHTEKKQS
ASSKGMITKR KSRGSTADEE EEHPYELLLT AETKKHTVVD KKTKGESSSG VAAGVQPQAW
PRKGPSSQDG QWPLSCQASS EFSSSHSEQY SSPDLQLVEI PKDQSRSSNN HSQTDEQDVP
VLDQFSGLLH GSSPVCEINE DPFRLISAVG KGGTERTAMQ LEDVETSESV QTSTADQNKV
VYSTIRHSCD NKLDPEILVH PHLSQHPGGT EDGDKSGVVG RVHVGGKSRA ELKLSRSLSK
SDSDLLTTSP TEDDTMGSRS ESLSNCTAGK KRLEKSPSFA SEWDEIEKIM SSIGEGIDFS
QEQQRMSGSR MLEQSVGEWL ESIGLQQYES KLLLNGFDDV RFLGCNVMED QDLREIGISD
PQHRRKLLQA ARSLPKVKSL GCDGTQPSVP AWLDSLGLQD YIQSFLSSGY SSIDSVKNLW
ELELVNVLKV NLLGHRKRII ASLADRPYEE PPQKPPRFSQ LRCQDLISQT SSPLSQSDSY
TGRSADLLLP LGDAGKKRHE GSHDTVSYPR TERLKEERHE SKLMLRPPSL AAPYAPVQHW
QHQPEKLIFE SCGYEANYLG SMLIKDLRGT ESTQDACAKM RKSTEHMKKI PTIILSITYK
GVKFIDASNK NVIAEHEIRN ISCAAQDPED LCTFAYITKD LQTSHHYCHV FSTIDVNLTY
EIILTLGQAF EVAYQLALQA QKSKPPGALT AETIETKSSK PVPKPRASMR KSAVPLPPDN
RCCNCHTCTT HRPSYLPLQS VSQGAKLEPS EVDQDSQSHA SVSWVVEPKQ DSKRTLSTN
//
