ID G1KAB9_ANOCA Unreviewed; 422 AA.
AC G1KAB9;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 2.
DT 27-MAR-2024, entry version 78.
DE RecName: Full=Fibromodulin {ECO:0000256|ARBA:ARBA00018230};
DE AltName: Full=Keratan sulfate proteoglycan fibromodulin {ECO:0000256|ARBA:ARBA00032216};
GN Name=FMOD {ECO:0000313|Ensembl:ENSACAP00000002079.2};
OS Anolis carolinensis (Green anole) (American chameleon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Dactyloidae; Anolis.
OX NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000002079.2, ECO:0000313|Proteomes:UP000001646};
RN [1] {ECO:0000313|Ensembl:ENSACAP00000002079.2, ECO:0000313|Proteomes:UP000001646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000002079.2,
RC ECO:0000313|Proteomes:UP000001646};
RG The Genome Sequencing Platform;
RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACAP00000002079.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Affects the rate of fibrils formation. May have a primary
CC role in collagen fibrillogenesis. {ECO:0000256|ARBA:ARBA00025136}.
CC -!- SUBUNIT: Binds to type I and type II collagen.
CC {ECO:0000256|ARBA:ARBA00011226}.
CC -!- SIMILARITY: Belongs to the small leucine-rich proteoglycan (SLRP)
CC family. SLRP class II subfamily. {ECO:0000256|ARBA:ARBA00005818}.
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DR AlphaFoldDB; G1KAB9; -.
DR STRING; 28377.ENSACAP00000002079; -.
DR Ensembl; ENSACAT00000002133.3; ENSACAP00000002079.2; ENSACAG00000002165.3.
DR eggNOG; KOG0619; Eukaryota.
DR GeneTree; ENSGT00940000157007; -.
DR HOGENOM; CLU_000288_186_4_1; -.
DR InParanoid; G1KAB9; -.
DR OrthoDB; 521898at2759; -.
DR TreeFam; TF334562; -.
DR Proteomes; UP000001646; Chromosome 4.
DR Bgee; ENSACAG00000002165; Expressed in skeletal muscle tissue and 5 other cell types or tissues.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0030199; P:collagen fibril organization; IEA:Ensembl.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR000372; LRRNT.
DR PANTHER; PTHR45712; AGAP008170-PA; 1.
DR PANTHER; PTHR45712:SF4; FIBROMODULIN; 1.
DR Pfam; PF00560; LRR_1; 1.
DR Pfam; PF13855; LRR_8; 3.
DR SMART; SM00364; LRR_BAC; 6.
DR SMART; SM00365; LRR_SD22; 3.
DR SMART; SM00369; LRR_TYP; 7.
DR SMART; SM00013; LRRNT; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 4.
PE 3: Inferred from homology;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000001646};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 121..155
FT /note="LRRNT"
FT /evidence="ECO:0000259|SMART:SM00013"
SQ SEQUENCE 422 AA; 47705 MW; 4039ABAC64F1C214 CRC64;
MPNLSASCLN TPCNISNIAA GSSWTTGNKI LPGISGCREV CGIMHWVSVL IIAGLCRVGF
SQYDDQYDDI FWLQQYLRSQ SSSYSYSPYY EDEIPPYSSY SYAPAESSVG EPVPEPPVSR
ECPQECECPP NFSSALYCDA RNLRYLPFVP SRMKYAYFQN NQITAIQEGA FDNATNLEWL
ALHSNQITSE KMGKRVFAKL KNLERLYLDH NNLTKMPTPL PRSLRELHLA YNQISKVPSN
ALEGLENLTA LYLSHNQIHE IGANLKGLKS LILADLSYNQ LRRVPDGLPS SLEQLYLEHN
HINTIPDDYF KISPKLLYVR MSHNSLTSEG LAPNAFNASS LLELDLSYNR LQKIPRVSTS
LENLYLQGNR INEFTINSFC TIVDIMNFSK LQVLRLDGND IHRNNVPSDA PLCLRWASVI
EI
//
