ID G1KB68_ANOCA Unreviewed; 713 AA.
AC G1KB68;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 2.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Glycosylphosphatidylinositol specific phospholipase D1 {ECO:0000313|Ensembl:ENSACAP00000002715.3};
GN Name=GPLD1 {ECO:0000313|Ensembl:ENSACAP00000002715.3};
OS Anolis carolinensis (Green anole) (American chameleon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Dactyloidae; Anolis.
OX NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000002715.3, ECO:0000313|Proteomes:UP000001646};
RN [1] {ECO:0000313|Ensembl:ENSACAP00000002715.3, ECO:0000313|Proteomes:UP000001646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000002715.3,
RC ECO:0000313|Proteomes:UP000001646};
RG The Genome Sequencing Platform;
RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACAP00000002715.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G1KB68; -.
DR STRING; 28377.ENSACAP00000002715; -.
DR Ensembl; ENSACAT00000002783.4; ENSACAP00000002715.3; ENSACAG00000002705.4.
DR eggNOG; KOG3637; Eukaryota.
DR GeneTree; ENSGT00390000013522; -.
DR HOGENOM; CLU_011756_0_0_1; -.
DR TreeFam; TF335726; -.
DR Proteomes; UP000001646; Chromosome 4.
DR Bgee; ENSACAG00000002705; Expressed in liver and 13 other cell types or tissues.
DR GO; GO:0031012; C:extracellular matrix; IBA:GO_Central.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0004621; F:glycosylphosphatidylinositol phospholipase D activity; IBA:GO_Central.
DR GO; GO:0006507; P:GPI anchor release; IBA:GO_Central.
DR Gene3D; 2.130.10.130; Integrin alpha, N-terminal; 2.
DR InterPro; IPR013517; FG-GAP.
DR InterPro; IPR001028; Gprt_PLipase_D.
DR InterPro; IPR013519; Int_alpha_beta-p.
DR InterPro; IPR028994; Integrin_alpha_N.
DR PANTHER; PTHR23221; GLYCOSYLPHOSPHATIDYLINOSITOL PHOSPHOLIPASE D; 1.
DR PANTHER; PTHR23221:SF7; PHOSPHATIDYLINOSITOL-GLYCAN-SPECIFIC PHOSPHOLIPASE D; 1.
DR Pfam; PF01839; FG-GAP; 3.
DR PRINTS; PR00718; PHPHLIPASED.
DR SMART; SM00191; Int_alpha; 6.
DR SUPFAM; SSF69318; Integrin alpha N-terminal domain; 1.
DR PROSITE; PS51470; FG_GAP; 3.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000001646};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT REPEAT 243..304
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 312..373
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 376..436
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REGION 166..188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 166..187
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 713 AA; 78755 MW; E4E180664780AFE7 CRC64;
MVADVSWHSL GIDQGFLRAM AAIDFHGSYA DAHSAGDFGG DVLSQFELDF DYLAPNWYVP
VKDLLSIYKE LYGQEVITEE TIVDCAHLQF LELYGEVIGI AKIYPFYARK SPFLVDKFHD
YFLGGVDDMA FASNNIFQQT SQILAHGTSG CFIPENPLYI RCKDEQRYPT SRSRPSKTEH
HSNKTSSLAK SVEKNINYTE RGVYFDMPAW ATNYLYFRNS AAAKGLTSVL TITQQESSHH
ITKPTASYFL KTPYAKLGWA MISADLNQDG YDDLVAGAPG YSRLGHIQIG RVYIIYGNKS
GLPHTDLDLD QEADEILEGN KPSGRFGSSI AALDFNEDGV LDLAVGAPSV GSQELSYRGF
VYIFFGNRRG GGFHKTPNIT IACQKIYCNF GWSLLAADVD GDGNHDLVVG SPYAPGRGKQ
RGFVASFYSF FNRSSQGQLS VSDADWIVKG QTDYAWFGSS LSSVQLQNRT LLLIGSPSWK
SCTGMRCYFS DDTRQAVGRV YGYIPPNKRS WFTLTGDMDM GNFGSSLATG FLSVEGILRH
VLVVGAPTQD SPSKFVFIPS VLHQAGAALM YDLREDTEPH LLSSFNGDRR FSRFGGDVHL
SDLNNDGLDE IIVTSPLRSK DIVAGVLEGE SARIYIYSGN QTVSGKVTNQ CKSWTTPCPE
DWAEYVIISP EEKSRFGSAV ITVKSGQQND IVVAAERSSV KARLSGRLFI YTF
//
