ID G1KDC0_ANOCA Unreviewed; 3452 AA.
AC G1KDC0;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 3.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=CUB and Sushi multiple domains 1 {ECO:0000313|Ensembl:ENSACAP00000004820.4};
GN Name=CSMD1 {ECO:0000313|Ensembl:ENSACAP00000004820.4};
OS Anolis carolinensis (Green anole) (American chameleon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Dactyloidae; Anolis.
OX NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000004820.4, ECO:0000313|Proteomes:UP000001646};
RN [1] {ECO:0000313|Ensembl:ENSACAP00000004820.4, ECO:0000313|Proteomes:UP000001646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000004820.4,
RC ECO:0000313|Proteomes:UP000001646};
RG The Genome Sequencing Platform;
RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACAP00000004820.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
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DR STRING; 28377.ENSACAP00000004820; -.
DR Ensembl; ENSACAT00000004928.4; ENSACAP00000004820.4; ENSACAG00000004617.4.
DR eggNOG; KOG4297; Eukaryota.
DR GeneTree; ENSGT00940000155701; -.
DR HOGENOM; CLU_000277_0_0_1; -.
DR InParanoid; G1KDC0; -.
DR TreeFam; TF316872; -.
DR Proteomes; UP000001646; Chromosome 1.
DR Bgee; ENSACAG00000004617; Expressed in testis and 5 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:1990708; P:conditioned place preference; IEA:Ensembl.
DR GO; GO:0008585; P:female gonad development; IEA:Ensembl.
DR GO; GO:0042593; P:glucose homeostasis; IEA:Ensembl.
DR GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR GO; GO:0007613; P:memory; IEA:Ensembl.
DR GO; GO:0035846; P:oviduct epithelium development; IEA:Ensembl.
DR GO; GO:0001964; P:startle response; IEA:Ensembl.
DR CDD; cd00033; CCP; 28.
DR CDD; cd00041; CUB; 13.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 28.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 13.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR PANTHER; PTHR45656:SF4; PROTEIN BETA CHAIN, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR45656; PROTEIN CBR-CLEC-78; 1.
DR Pfam; PF00431; CUB; 13.
DR Pfam; PF00084; Sushi; 28.
DR SMART; SM00032; CCP; 28.
DR SMART; SM00042; CUB; 13.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 28.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 13.
DR PROSITE; PS01180; CUB; 13.
DR PROSITE; PS50923; SUSHI; 28.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00302}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001646};
KW Sushi {ECO:0000256|PROSITE-ProRule:PRU00302};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 3376..3397
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 31..92
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 96..200
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 235..296
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 299..410
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 413..470
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 472..580
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 583..644
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 646..754
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 759..816
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 818..928
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 931..990
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 992..1100
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1103..1163
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1165..1274
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1277..1337
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1339..1447
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1450..1511
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1513..1621
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1627..1688
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1690..1798
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1801..1860
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1862..1970
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1973..2032
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2034..2145
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 2144..2205
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2207..2318
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 2318..2380
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2381..2442
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2443..2507
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2508..2565
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2566..2623
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2624..2681
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2682..2744
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2745..2802
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2806..2863
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2864..2922
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2923..2982
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2983..3040
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 3041..3098
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 3102..3160
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 3161..3220
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DISULFID 441..468
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 787..814
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 1165..1192
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00059"
FT DISULFID 2536..2563
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 2594..2621
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 2652..2679
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 2715..2742
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 2773..2800
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 2834..2861
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 2893..2920
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 3011..3038
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 3069..3096
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 3131..3158
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
SQ SEQUENCE 3452 AA; 378064 MW; E63BBAF7D7934812 CRC64;
ACLIVLVIIQ IKGIRLYGSH IQLKLITKLY HTCGNPGEIP KGVLHGTRFN IGDKIRYSCI
TGYILEGHAM LTCIMSPGNG ALWDFPVPFC RAEGACGGTL RGTSGIISSP HFPSEYDNNA
DCTWTILAEP GDTIALIFTD FQLEEGYDFL EISGTEAPSI WLTGMNLPSP VISSKNWLRL
HFTSDSNHRR KGFNAQFQVK KAIELKSRGV KMLPNKDSNH KNSVLSQGGD AVASDTCPDP
GIPENGKRAG LEFRVGASVQ FSCDDNYVLQ GAKSITCQKV TDTLAAWSDH RPICRARTCG
SNLRGPSGII TSPNYPVQYE DNAHCVWVIT TLDPEKVIKL AFEEFELERG YDTLTVGDAG
KVGDTRTVLY VLTGSSVPDL IVSMSNQMWL HLQSDDSIGS PGFKAVYQEI EKGGCGDPGI
PSYGKRTGNS FQHGDTLTFE CQAAFELVGE RMITCQQNNQ WSGNKPSCVF SCFFNFTTPS
GIILSPNYPE EYGNNMNCVW LIISEPGSRI HLIFNDFDVE PQFDYLTMKD DGISDLPALG
TFSGNDVPSQ IASNGHIVRL EFQSDHSTTG RGFNITYTTF GQNECHDPGI PINGRRFGDR
FLLGSSVSFH CDDGFVKTQG SETITCIMQD GNVVWSSTVP RCEAPCGGHL TASSGVILPP
GWPGYYKDSL NCEWVIEARQ GHSIKITFDK FQTEVNYDTL EVRDGSSSSS PLIGEYHGTQ
APQFLISTGN FMYLLFTTDN SRSSVGFLIH YESVTLESDS CLDPGIPVNG HRRGNNFSIR
STVTFSCDPG YTLSDDEPLV CERNHQWNHA LPSCDALCGG YIHGRSGTLL SPGFPDFYPN
SLNCTWTIEV SHGKGVQLIF HTFHLESSHD YLLITEDGSF TEPVARLTGS VLPPTIKAGL
FGNFTAQLRF ISDFSISYEG FNITFSEYDL EPCDDPGVPA FSRRIGFHFG VGDSLTFSCF
PGYRLEGANK LTCLGGGRRV WSAPLPRCVA ECGASVSGNE GTLLSPNFPS NYDNNHECIY
KIETEPGKGI HLRARTFQLY EGDTVKVYDG KDSSSRLLGT FSKNELIGLI LNSTSNHLWI
EFNTNGSDTD QGFQLTYTSF DLVKCEDPGT PNFGYKIRDD GHFTETVILY SCNPGYMMHG
SSTITCLSGD RRVWDKPLPT CIAECGGRIH AVTSGRILSP GYPAPYDNNL HCTWIIEADP
GRTISLHFIV FDTEVAHDIL KVWDGPVESS ILLKEWSGSA LPEDIYSTFN SLTLQFDSDF
FISKSGFSIQ FSTSVASTCN DPGTPQNGSR YGDSREPGDT ITFQCDPGYQ LQGQDKITCV
QLNNRFFWQP DAPTCIAACG GNLTGPAGVI LSPNYPQPYP PGKECDWRIK VSPDFVIALI
FKSFNMEPSY DFLHIYEGED SNSPLIGSFQ GSQAPERIES SGNSLFLAFR SDASVGMSGF
AIEYKEKPRE ACFDPGNIMN GTRIGADLKL GSSITYQCDS GYKIIDPSTI TCEIGIDGKP
AWNRVLPSCN APCGGQYTGS DGVVLSPNYP QNYTVGQTCQ YSITVPKEFV VFGQFAYFQT
ALNDVVELFD GEHAQTRLLS SLSGSHSGET LPLATSNQIL LRFSAKSGAS ARGFHFVYQA
VPRTSDTQCS SVPEPRYGRR IGSEFSAGSV VRFECSPGYL LQGSKAIRCQ SVPNALAQWN
DTVPSCVVPC SRNFTERRGT ILSPGYPEPY GNGLNCVWKI IVTEGSGIQI QVISFATEHN
WDSLEIYDGG DMISPRLGSF SGTTVPALLN STSNQLYLHF HSDISVAAAG FHLEYKTVGL
AACSEPVIPS NGFKIGDRYL VNDVLSFQCE PGYTLQGRSH ISCMPGTIRR WNYPSPLCIA
KCGGTLTNLA GVILSPGFPG NYPSNLGCTW KLLLSVGYGA HIQFLNFSTE ANHDFLEIQN
GPYHTSSMIG QFSGTDLPPS LLSTTHETLI HFYSDHSENR QGFKLVYQGY ELQNCPDPPP
FFNGYIINSD YSVGQSISFE CYPGYVLIGH SVLTCHHGIN RNWNYPFPKC EAPCGYNVTS
SNGTVYSPGF PDEYPNSKDC TWLITVPQGH GIYINFTLLQ TELVNDYIAV WDGPDQNSPQ
LGVFSGNTAL ETAYSSSNQV LLKFHSDFST GGFFVLNFHA YQLQKCQPPP AVPEADRLTE
DDDFEIGDFA KYKCHPGYTL VGNDMMFCKL KAQLQFEGSP PFCEAQCPAN EVRPDSSGVI
LSPGYPGNYP HSQTCSWTLK VEPNYNISVF VETFQSEKQF DELELFDGPS GQSPLLVALS
GNHTGQLNYT SRSNQLYLRW STDHATSKKG FKIRYSAPYC SLNHVVKNGG IINKTRNTVG
STVHYYCKPG YRIIGRSNAT CRRHPNGMYQ WDSPTPLCQA VSCGMPVSPG NGSVWGNEFV
LGSKVIYECN EGFKLESSQQ TTAVCQEDGL WSNKGKPPVC KPVTCPSIES LLSEHVIWRL
ISGLVNEFGA QVMLSCSPGY YLEGQRLMLC KTNGTWSGAD ERPKCKVISC GSLPSPPNGN
KIGTLTVYGA TAIFTCNTGY TLVGSHVREC LANGLWSGTE TQCLAGHCGS PDPIVNGHIS
GDGFSYRDTV VYQCNPGFRL VGTSVRICLQ DHKWSGQTPV CVSITCGHPG NPAHGMTNGS
EFNLNDVVNF TCNTGYLLQG APQAQCRSNG QWSSSLPTCR VVNCSDPGFV ENAVRHGQQN
FPESFKYGIS VVYHCKKGFY LLGSSTLTCK ANSLWDRSLP KCLPISCGQP GIPTNAILSG
DKFTYGSTVH YSCVGSRTLL GNSSRVCQEN SRWSGNLPHC SGNTPGYCDD PGVPSHGSRL
GDEFKIKSLL RFSCEMGYRL RGSPERTCLL NGSWSGFQPV CEAVSCGNPG TPANGKIIYS
DGISFSNSVI YACWDGYKTS GLTTRHCTAN GTWTGTTPDC AVISCGDPGE VPNGIQFGND
FTFNKTVSYQ CNPGHLMEPV GAPTIRCTKD GTWNQSKPIC KAITCGPPPQ VLYGKVEGSD
FQWGSSISYS CADGYHVSNS AILSCEGRGV WRGEIPQCLP VFCGEPGVPT EGRLNGKSFT
YRSEVSFQCR LPLILIGSSR RICQADGSWS GIQPTCIDPA HNSCPDPGTP HYGLQNSSRG
YEVGSRVFFR CRKGYHIQGS TTRTCLANLT WSGMQPECIP HACRQPETPA NVDVKAIDLP
TLGYTLVYTC QPGFFLTGGS EHRTCKPDMK WTGKSPVCKS KGVREVNETI TKTPVPSDVF
FINSLWKGFY EHLGKRQPAT LTVDWFNATS SKVNATFIEA SNTQLKLSGI YKKEEAHLLL
KIYQVKNPRD GFTSKLQNDK WALDGYVSSG LERGIFTYQG DIHGKDFGKF MLRRQSPLSV
DTDHPNHYYG TNSSSVAAAI LVPFFALILS GFAFYLYKHR TRPKVQYNGY AGHENSNGQA
SFENPMYDTN LKPTEAKAVR FDTTLNTVCT VV
//
