ID G1KI07_ANOCA Unreviewed; 743 AA.
AC G1KI07;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 3.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSACAP00000008467.4};
GN Name=LOC100567190 {ECO:0000313|Ensembl:ENSACAP00000008467.4};
OS Anolis carolinensis (Green anole) (American chameleon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Dactyloidae; Anolis.
OX NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000008467.4, ECO:0000313|Proteomes:UP000001646};
RN [1] {ECO:0000313|Ensembl:ENSACAP00000008467.4, ECO:0000313|Proteomes:UP000001646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000008467.4,
RC ECO:0000313|Proteomes:UP000001646};
RG The Genome Sequencing Platform;
RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACAP00000008467.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_003218098.1; XM_003218050.3.
DR RefSeq; XP_008104038.1; XM_008105831.2.
DR AlphaFoldDB; G1KI07; -.
DR Ensembl; ENSACAT00000008649.4; ENSACAP00000008467.4; ENSACAG00000008669.4.
DR GeneID; 100567190; -.
DR KEGG; acs:100567190; -.
DR eggNOG; KOG1721; Eukaryota.
DR GeneTree; ENSGT01100000263521; -.
DR HOGENOM; CLU_002678_44_5_1; -.
DR InParanoid; G1KI07; -.
DR TreeFam; TF343410; -.
DR Proteomes; UP000001646; Chromosome 2.
DR Bgee; ENSACAG00000008669; Expressed in embryonic post-anal tail and 13 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd07765; KRAB_A-box; 1.
DR Gene3D; 6.10.140.140; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 18.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24393:SF163; -; 1.
DR PANTHER; PTHR24393; ZINC FINGER PROTEIN; 1.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF00096; zf-C2H2; 17.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 18.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 10.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 18.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 19.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001646};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 95..184
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 169..198
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 227..254
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 255..282
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 283..310
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 311..338
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 339..366
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 367..394
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 395..422
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 423..450
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 451..478
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 479..506
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 507..534
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 535..562
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 563..590
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 591..618
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 619..646
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 647..674
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 675..702
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 703..730
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
SQ SEQUENCE 743 AA; 84760 MW; 11A1177F16E550CD CRC64;
MMNLAKEESV PSALLKTAGE NSMKVEKEDT AICEKRFLER VAETENHSSK TKWIVQNKDG
ASSSMGDAVK TWSVYTTTSL HGDAPKAALV RPDQVTFEDV AVHFTEEEWA LLDPDQRALH
WEVMDENLGL VSSLSGDGQD NANEEDPYWI SDLFGISHQE ITQKGKEKNK CPCVACEGLF
TSKASINRHR KTRTVEKSSK GSDREKSPGF RKCLISHEKI PSKEKPFKCL ECGKSFVWRS
HLMIHRRTHT GEKPFKCLWC GKSLSRRSHL MDHLRTHTGQ KPFKCSECGK RFSQKRSLTC
HQATHTGEKP FKCLECGKRF SQKRNLIHHQ ATHTEKKPFE CLECGKSFSQ KRKLTHHQAT
HTEKKPFECA ECGKSFFWKI SLMHHQAMHT GEKPFKCMEC GKSFSRKAGL SCHQAVHTGE
KPFKCLECGK TFSWKTGLTY HQATHTGEKP FECLECGKTF RWKTGLTYHQ ATHTGEKPFK
CLECGKSFNW KMDLVRHQAI HVGEKLFKCL ECGKSFSQKR NLAHHQVMHS GEKPYKCSEC
GKSFSWKIDL SRHQAIHTGE KPFKCLECGK SFTQKTGLTY HQATHTGEKP FKCLECGKSF
SWKTGLTYHQ ATHSGEKPYK CLECGKSFSQ KRSLNHHQAM HTGERPFKCL ECGKSFSWKM
DLVRHQTTHT GEKPFKCLEC GKCFTQKTGL TRHQVTHTGE KPFKCLECGK SFSRKMHLTR
HQANHTGGTT LGKVKEEIIS VII
//
