ID G1KIJ0_ANOCA Unreviewed; 194 AA.
AC G1KIJ0;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 2.
DT 27-MAR-2024, entry version 74.
DE RecName: Full=ADP-ribosylation factor-like protein 6 {ECO:0000256|ARBA:ARBA00019766};
GN Name=ARL6 {ECO:0000313|Ensembl:ENSACAP00000008967.3};
OS Anolis carolinensis (Green anole) (American chameleon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Dactyloidae; Anolis.
OX NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000008967.3, ECO:0000313|Proteomes:UP000001646};
RN [1] {ECO:0000313|Ensembl:ENSACAP00000008967.3, ECO:0000313|Proteomes:UP000001646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000008967.3,
RC ECO:0000313|Proteomes:UP000001646};
RG The Genome Sequencing Platform;
RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACAP00000008967.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium membrane
CC {ECO:0000256|ARBA:ARBA00004522}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004522}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004522}.
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Arf family.
CC {ECO:0000256|ARBA:ARBA00010290, ECO:0000256|RuleBase:RU003925}.
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DR AlphaFoldDB; G1KIJ0; -.
DR STRING; 28377.ENSACAP00000008967; -.
DR Ensembl; ENSACAT00000009159.4; ENSACAP00000008967.3; ENSACAG00000009179.4.
DR eggNOG; KOG0070; Eukaryota.
DR GeneTree; ENSGT00940000156459; -.
DR HOGENOM; CLU_040729_9_1_1; -.
DR InParanoid; G1KIJ0; -.
DR TreeFam; TF105466; -.
DR Proteomes; UP000001646; Chromosome 3.
DR Bgee; ENSACAG00000009179; Expressed in dewlap and 13 other cell types or tissues.
DR GO; GO:0005930; C:axoneme; IBA:GO_Central.
DR GO; GO:0060170; C:ciliary membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015630; C:microtubule cytoskeleton; IEA:Ensembl.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0060271; P:cilium assembly; IBA:GO_Central.
DR GO; GO:0006886; P:intracellular protein transport; IBA:GO_Central.
DR GO; GO:0061512; P:protein localization to cilium; IBA:GO_Central.
DR GO; GO:0016192; P:vesicle-mediated transport; IBA:GO_Central.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:Ensembl.
DR CDD; cd04157; Arl6; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR041839; Arl6.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR006689; Small_GTPase_ARF/SAR.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR11711; ADP RIBOSYLATION FACTOR-RELATED; 1.
DR PANTHER; PTHR11711:SF21; ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 6; 1.
DR Pfam; PF00025; Arf; 1.
DR PRINTS; PR00328; SAR1GTPBP.
DR SMART; SM00177; ARF; 1.
DR SMART; SM00178; SAR; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51417; ARF; 1.
DR PROSITE; PS51419; RAB; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU003925};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003925};
KW Reference proteome {ECO:0000313|Proteomes:UP000001646}.
SQ SEQUENCE 194 AA; 22038 MW; 442C2351DBE56B73 CRC64;
MGLFDKLAGW LGLKKKEVHV LCLGLDNSGK TTIINKLKPS NAQAQDIVPT IGFSIEKFKT
SSLSFTVFDM SGQGRYRNLW EHYYKDCQAI IFVIDSSDKL RMVVAKEELD TLMNHPDLKH
RRIPILFFAN KMDLRDAVSS VKVSHLLSLE DIKDKPWHIC ASDAIKGEGL QEGVDWLQDQ
ITQSNSINED MKNQ
//
