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Database: UniProt
Entry: G1KMP2_ANOCA
LinkDB: G1KMP2_ANOCA
Original site: G1KMP2_ANOCA 
ID   G1KMP2_ANOCA            Unreviewed;       628 AA.
AC   G1KMP2;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2013, sequence version 2.
DT   28-MAR-2018, entry version 53.
DE   SubName: Full=Potassium voltage-gated channel subfamily C member 4 {ECO:0000313|Ensembl:ENSACAP00000012473};
GN   Name=KCNC4 {ECO:0000313|Ensembl:ENSACAP00000012473};
OS   Anolis carolinensis (Green anole) (American chameleon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata;
OC   Toxicofera; Iguania; Dactyloidae; Anolis.
OX   NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000012473, ECO:0000313|Proteomes:UP000001646};
RN   [1] {ECO:0000313|Ensembl:ENSACAP00000012473, ECO:0000313|Proteomes:UP000001646}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000012473};
RG   The Genome Sequencing Platform;
RA   Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA   Lander E.S., Lindblad-Toh K.;
RT   "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL   Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSACAP00000012473}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2011) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the potassium channel family.
CC       {ECO:0000256|SAAS:SAAS00692852}.
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DR   RefSeq; XP_003220283.1; XM_003220235.3.
DR   STRING; 28377.ENSACAP00000012473; -.
DR   Ensembl; ENSACAT00000012729; ENSACAP00000012473; ENSACAG00000012721.
DR   GeneID; 100563924; -.
DR   KEGG; acs:100563924; -.
DR   CTD; 3749; -.
DR   eggNOG; KOG3713; Eukaryota.
DR   eggNOG; COG1226; LUCA.
DR   GeneTree; ENSGT00760000118846; -.
DR   InParanoid; G1KMP2; -.
DR   KO; K04890; -.
DR   OrthoDB; EOG091G0EJL; -.
DR   TreeFam; TF352511; -.
DR   Proteomes; UP000001646; Chromosome 4.
DR   Bgee; ENSACAG00000012721; -.
DR   GO; GO:0043679; C:axon terminus; IEA:Ensembl.
DR   GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR   GO; GO:0031594; C:neuromuscular junction; IEA:Ensembl.
DR   GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:InterPro.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IBA:GO_Central.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IBA:GO_Central.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   GO; GO:0046928; P:regulation of neurotransmitter secretion; IEA:Ensembl.
DR   Gene3D; 1.20.120.350; -; 1.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR003968; K_chnl_volt-dep_Kv.
DR   InterPro; IPR003974; K_chnl_volt-dep_Kv3.
DR   InterPro; IPR005405; K_chnl_volt-dep_Kv3.4.
DR   InterPro; IPR021105; K_chnl_volt-dep_Kv3_ID.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   InterPro; IPR003131; T1-type_BTB.
DR   InterPro; IPR028325; VG_K_chnl.
DR   InterPro; IPR027359; Volt_channel_dom_sf.
DR   PANTHER; PTHR11537; PTHR11537; 1.
DR   Pfam; PF02214; BTB_2; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF11404; Potassium_chann; 1.
DR   PRINTS; PR00169; KCHANNEL.
DR   PRINTS; PR01583; KV34CHANNEL.
DR   PRINTS; PR01491; KVCHANNEL.
DR   PRINTS; PR01498; SHAWCHANNEL.
DR   SMART; SM00225; BTB; 1.
DR   SUPFAM; SSF54695; SSF54695; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000001646};
KW   Ion channel {ECO:0000256|SAAS:SAAS00417203};
KW   Ion transport {ECO:0000256|SAAS:SAAS00417186};
KW   Membrane {ECO:0000256|SAAS:SAAS00085096, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|SAAS:SAAS00417282};
KW   Potassium channel {ECO:0000256|SAAS:SAAS00417246};
KW   Potassium transport {ECO:0000256|SAAS:SAAS00417240};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001646};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00084820,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00084701,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00417268};
KW   Voltage-gated channel {ECO:0000256|SAAS:SAAS00984201}.
FT   TRANSMEM    221    240       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    378    399       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    420    437       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    449    478       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       36    138       BTB. {ECO:0000259|SMART:SM00225}.
SQ   SEQUENCE   628 AA;  69341 MW;  C32945E4E7B19FF3 CRC64;
     MLSSVCVSSY RGRKSGNKPP SKSCLKEEMA KGEDTEKITI NVGGTRHETY KSTLRTLPGT
     RLAWLADPEV PGPTEDAQHE FFFDRHPGIF AYVLNYYRTG KLHCPADICG PLFEEELTYW
     GIDETDVEPC CWMTYRQHRD AEEALDIFEN PEAGSGAAGE EAEEDEGARE ATLQQLGLDD
     RPATGATAGT AGAGVTGGGG CCRNWQPRMW ALFEDPYSSK AARVIAFASL FFILVSITTF
     CLETHEAFIT HSNTTETVVD GNTTQFIVVH EMETEPVLTY IEGVCVLWFT LEFLVRIMCC
     PDKLVFVKNL LNIIDFVAIL PFYVEVGLSG LSSKAARDVL GFLRVVRFVR ILRIFKLTRH
     FVGLRVLGHT LRASTNEFLL LIIFLALGVL IFATMIYYAE RIGAEPNDPS GSHHTHFKNI
     PIGFWWAVVT MTTLGYGDMY PKTWSGMLVG ALCALAGVLT IAMPVPVIVN NFGMYYSLAM
     AKQKLPKKKK KHIPRPAPLD SPTYCRSDDN SPHNSVQSCN SPLAAATATT AAGMMASKRS
     DTKQNGDANV VLSDEEQPLS SPCEEKRPMR RSSTRDKTKK AATCFLLSTG DFSCTADGGI
     QKAKLPYVLS GQFLQPLEGR MNHHRSSL
//
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