ID G1KP71_ANOCA Unreviewed; 221 AA.
AC G1KP71;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 2.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Charged multivesicular body protein 4C {ECO:0000313|Ensembl:ENSACAP00000013544.3};
GN Name=CHMP4C {ECO:0000313|Ensembl:ENSACAP00000013544.3};
OS Anolis carolinensis (Green anole) (American chameleon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Dactyloidae; Anolis.
OX NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000013544.3, ECO:0000313|Proteomes:UP000001646};
RN [1] {ECO:0000313|Ensembl:ENSACAP00000013544.3, ECO:0000313|Proteomes:UP000001646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000013544.3,
RC ECO:0000313|Proteomes:UP000001646};
RG The Genome Sequencing Platform;
RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACAP00000013544.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the SNF7 family.
CC {ECO:0000256|ARBA:ARBA00006190}.
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DR RefSeq; XP_003219592.1; XM_003219544.2.
DR AlphaFoldDB; G1KP71; -.
DR STRING; 28377.ENSACAP00000013544; -.
DR Ensembl; ENSACAT00000013822.4; ENSACAP00000013544.3; ENSACAG00000013793.4.
DR GeneID; 100553838; -.
DR KEGG; acs:100553838; -.
DR CTD; 92421; -.
DR eggNOG; KOG1656; Eukaryota.
DR GeneTree; ENSGT00940000159257; -.
DR HOGENOM; CLU_071097_0_0_1; -.
DR InParanoid; G1KP71; -.
DR OrthoDB; 5360005at2759; -.
DR TreeFam; TF314269; -.
DR Proteomes; UP000001646; Chromosome 4.
DR Bgee; ENSACAG00000013793; Expressed in lung and 10 other cell types or tissues.
DR GO; GO:1904930; C:amphisome membrane; IEA:Ensembl.
DR GO; GO:0009898; C:cytoplasmic side of plasma membrane; IBA:GO_Central.
DR GO; GO:0000815; C:ESCRT III complex; IBA:GO_Central.
DR GO; GO:0090543; C:Flemming body; IEA:Ensembl.
DR GO; GO:0000776; C:kinetochore; IEA:Ensembl.
DR GO; GO:0005828; C:kinetochore microtubule; IEA:Ensembl.
DR GO; GO:0005765; C:lysosomal membrane; IEA:Ensembl.
DR GO; GO:0005771; C:multivesicular body; IBA:GO_Central.
DR GO; GO:0032585; C:multivesicular body membrane; IEA:Ensembl.
DR GO; GO:0005643; C:nuclear pore; IEA:Ensembl.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR GO; GO:0009838; P:abscission; IEA:Ensembl.
DR GO; GO:0097352; P:autophagosome maturation; IEA:Ensembl.
DR GO; GO:1902774; P:late endosome to lysosome transport; IEA:Ensembl.
DR GO; GO:0032511; P:late endosome to vacuole transport via multivesicular body sorting pathway; IBA:GO_Central.
DR GO; GO:0061952; P:midbody abscission; IEA:Ensembl.
DR GO; GO:0044878; P:mitotic cytokinesis checkpoint signaling; IEA:Ensembl.
DR GO; GO:0007080; P:mitotic metaphase chromosome alignment; IEA:Ensembl.
DR GO; GO:0032466; P:negative regulation of cytokinesis; IEA:Ensembl.
DR GO; GO:0031468; P:nuclear membrane reassembly; IEA:Ensembl.
DR GO; GO:0001778; P:plasma membrane repair; IEA:Ensembl.
DR GO; GO:0010824; P:regulation of centrosome duplication; IEA:Ensembl.
DR GO; GO:1901673; P:regulation of mitotic spindle assembly; IEA:Ensembl.
DR GO; GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IEA:Ensembl.
DR GO; GO:0090611; P:ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway; IEA:Ensembl.
DR GO; GO:0006900; P:vesicle budding from membrane; IBA:GO_Central.
DR GO; GO:0046761; P:viral budding from plasma membrane; IEA:Ensembl.
DR GO; GO:0039702; P:viral budding via host ESCRT complex; IEA:Ensembl.
DR Gene3D; 6.10.250.1710; -; 1.
DR Gene3D; 1.10.287.1060; ESAT-6-like; 1.
DR InterPro; IPR005024; Snf7_fam.
DR PANTHER; PTHR22761; CHARGED MULTIVESICULAR BODY PROTEIN; 1.
DR PANTHER; PTHR22761:SF77; CHARGED MULTIVESICULAR BODY PROTEIN 4C; 1.
DR Pfam; PF03357; Snf7; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001646}.
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 179..221
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 202..221
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 221 AA; 24959 MW; 038B330CAF478578 CRC64;
MSKIQKFFKG GGGGGFSKGK GKGGPSPQEA LARLRETEEM LTKKQEYLEA RIAKELALAK
KHGTRDKRAA LQALKRKKRY EKQLTQIDGT LSTIEFQREA LENSYTNTEV FKNMGYAAQA
MKKVHENMDL DKIDDMMQDI TEQQDIAQEI TEALTRKLGD DFDEDELLAE LEELEQEELN
SKMTNVRLPS VPATPLPTHP ASSKKRVEDD DDMKHLAAWA S
//
