ID G1KPL9_ANOCA Unreviewed; 1033 AA.
AC G1KPL9;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 3.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Contactin 2 {ECO:0000313|Ensembl:ENSACAP00000013947.4};
GN Name=CNTN2 {ECO:0000313|Ensembl:ENSACAP00000013947.4};
OS Anolis carolinensis (Green anole) (American chameleon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Dactyloidae; Anolis.
OX NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000013947.4, ECO:0000313|Proteomes:UP000001646};
RN [1] {ECO:0000313|Ensembl:ENSACAP00000013947.4, ECO:0000313|Proteomes:UP000001646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000013947.4,
RC ECO:0000313|Proteomes:UP000001646};
RG The Genome Sequencing Platform;
RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACAP00000013947.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G1KPL9; -.
DR STRING; 28377.ENSACAP00000013947; -.
DR Ensembl; ENSACAT00000014233.4; ENSACAP00000013947.4; ENSACAG00000013863.4.
DR eggNOG; KOG3513; Eukaryota.
DR GeneTree; ENSGT00940000159193; -.
DR HOGENOM; CLU_005756_0_0_1; -.
DR OrthoDB; 3073820at2759; -.
DR TreeFam; TF351103; -.
DR Proteomes; UP000001646; Chromosome 4.
DR Bgee; ENSACAG00000013863; Expressed in testis and 7 other cell types or tissues.
DR GO; GO:0030424; C:axon; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0098632; F:cell-cell adhesion mediator activity; IBA:GO_Central.
DR GO; GO:0007411; P:axon guidance; IBA:GO_Central.
DR GO; GO:0070593; P:dendrite self-avoidance; IBA:GO_Central.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IBA:GO_Central.
DR CDD; cd00063; FN3; 3.
DR CDD; cd04969; Ig5_Contactin; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 10.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR44170:SF28; CONTACTIN-2; 1.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR Pfam; PF00041; fn3; 3.
DR Pfam; PF07679; I-set; 2.
DR Pfam; PF13927; Ig_3; 3.
DR SMART; SM00060; FN3; 4.
DR SMART; SM00409; IG; 6.
DR SMART; SM00408; IGc2; 5.
DR SUPFAM; SSF49265; Fibronectin type III; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 6.
DR PROSITE; PS50853; FN3; 4.
DR PROSITE; PS50835; IG_LIKE; 6.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Reference proteome {ECO:0000313|Proteomes:UP000001646};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..15
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 16..1033
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5032667740"
FT DOMAIN 29..114
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 125..220
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 231..302
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 319..403
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 409..496
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 501..595
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 602..700
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 705..802
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 807..904
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 908..1000
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 886..913
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1033 AA; 113910 MW; F63F756E331E6D7A CRC64;
LVPLLLFCIL SPSYAVWWPA ESTVRNYGPV FEEQPRNTLF PEGSSEEQIL LTCQARASPP
ATYRWKLNGT EIKIETNSRY RLNGGNLVIS NPVKLKDAGF YQCVASNSVG TVVSREAYVR
FGFLQEFSTE ERDPVRGTEG WGVMFTCSPP PHFPGIEYRW FVNDFPNFIS TDRRRFISQA
TGNLYIAKTE ASDLGNYSCF ATGHIDSFKK SVFSTSSQLS LVREDSRPYA PTIKAKFPSD
TFALAGQLVS LECFAFGNPV PQIRWRKLDG GQSSRWITTE PLLEFKEVSF EDEGTYECEA
ENIQGKDTYR GRIIIQAQPE WLKVISDKEA DIGADLHWSC AAAGKPRPTI RWLRNGRPLT
SQNRIEVNGG DLRIFKLTMD DSGMYQCVGE NKHGSTYASA ELYVQAFAPD FRLNPVRRLI
PAARGGEIII HCQPKAAPKA NIIWTKGTEL LNNGSRITIT PSGTLIIRNI SKSDEGKYTC
FAENFMGKAN STGTLSVRDA TKITLAPSSA DINVGENITL KCHASHDPTM DLTFTWCLDD
LLIDISKSEG HYKRASTKEN IGDLMVLNAQ LKHAGRYTCT AQTVVDSASE SATLVVRGPP
GPPGGLVVTD IKDTTVQLSW SRGFDNHSPI AKYVIQVRTP IFSHWKQART NPANIEGNSE
TAQVGNLIPW MDYEFRVLAS NILGVGEPSM PSAKIRTKEA APTVAPSGLN GGGGAPGELI
INWTPMQREY QNGDGFGYNL TFRKEGTQVW KTATVLGAES LHYVYRNESI APYTPFEVKI
KAFNKKGEGP ESLVSIVHSA EEEPRVAPSN ITVNSVMATE MDITWNSVED HDMNGVLLGY
EIRYWKHGDK EEAADRVRTA GLVSSAHVTD LHPNTKYHVA VRAYNRAGTG PASNPTSFTT
TKPPPRRPPD NISWKFSSSS VSIKWDPVVA KADESAVTGY KMLYQPDLHS APILYKISNN
WIEIPVPEDS THAVVQIRTT GPGGDGVPAE VRILRNSGTS MMVKNSAAHP ITQTAVALTH
SLIMFALIGS LEL
//
