ID G1KRD4_ANOCA Unreviewed; 730 AA.
AC G1KRD4;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 2.
DT 27-MAR-2024, entry version 74.
DE RecName: Full=Leucine rich repeats and death domain containing 1 {ECO:0008006|Google:ProtNLM};
OS Anolis carolinensis (Green anole) (American chameleon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Dactyloidae; Anolis.
OX NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000015374.3, ECO:0000313|Proteomes:UP000001646};
RN [1] {ECO:0000313|Ensembl:ENSACAP00000015374.3, ECO:0000313|Proteomes:UP000001646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000015374.3,
RC ECO:0000313|Proteomes:UP000001646};
RG The Genome Sequencing Platform;
RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACAP00000015374.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G1KRD4; -.
DR STRING; 28377.ENSACAP00000015374; -.
DR Ensembl; ENSACAT00000015687.3; ENSACAP00000015374.3; ENSACAG00000015646.3.
DR eggNOG; KOG0619; Eukaryota.
DR GeneTree; ENSGT00940000156270; -.
DR HOGENOM; CLU_022747_0_0_1; -.
DR InParanoid; G1KRD4; -.
DR TreeFam; TF351429; -.
DR Proteomes; UP000001646; Chromosome 6.
DR Bgee; ENSACAG00000015646; Expressed in brain and 2 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central.
DR GO; GO:0007165; P:signal transduction; IBA:GO_Central.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 5.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR45752; LEUCINE-RICH REPEAT-CONTAINING; 1.
DR PANTHER; PTHR45752:SF149; LEUCINE-RICH REPEAT-CONTAINING PROTEIN 39; 1.
DR Pfam; PF13855; LRR_8; 4.
DR PRINTS; PR00019; LEURICHRPT.
DR SMART; SM00364; LRR_BAC; 11.
DR SMART; SM00365; LRR_SD22; 9.
DR SMART; SM00369; LRR_TYP; 14.
DR SUPFAM; SSF52058; L domain-like; 2.
DR PROSITE; PS51450; LRR; 9.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000001646};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REGION 1..79
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 31..56
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 730 AA; 83710 MW; 2A7E84026696A6C2 CRC64;
MSGEKEEEQT ADINLEGIIE ASPDEIPEPN ATSDMEQSQL PTDMTEISST TSLHKEKSGA
SQEKLSESFL GASQRDPEKE ALRSAEKLES IKKISEILMS EAKDTEIIAY LYAEGYTDLP
HDFLEGQTRK KLLHSIESAT TPQKISADML PEMMLDDFTI QLNAKGLLEI PTGVLDMKML
NYLYLNNNEI KIIPKEIRQL TGLEILSIER NRLTSLPPEI GLLQNLRTLN LRHNQLTGLP
DEFSQLSELK YLLFSHNNIE KFPSALTTLR SLEVLDLSGN KVTLIENLTE MKKLNILYLN
ENKMKIFPKA LCYLPNISKL NLSENLIQSL PKEIEELKTL KELSLSNNRL IFLPIQLFQL
IQLEKMRLDC NQLESLSDKV ENLQKLQDLN LSKNLFQNIT DNISKCTMLE RLNLSDNQFK
KLPNNLYQLK YLKELHLNRN QLILLDEHIA FNKELSVLEV SENALMYIPV EIKNCTEIIK
IDLSCNKLAL FPMGLCALVA LRHLNLSGNY ISEITTEISF IKYLQYLNLS KNKLPSFSIH
LCTLSRLNYL DLSYNQISSI PTNVQKMKSL RTLLLHHSKF ILFPRELCAL NQLKVLDLSE
NKIQFIPSDI KDLEELKELN LSNNNFASFP VEICQILSLQ KLTICQKNGL KLKSLPEEIS
KLLVLKELDI SYNELQEMPK SIGEIKTLVT LIANNNFFKK LPSSFSSLRN LQHLNLKGKW
YAKYHREIQT
//
