ID G1KTU6_ANOCA Unreviewed; 328 AA.
AC G1KTU6;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 2.
DT 27-MAR-2024, entry version 67.
DE RecName: Full=Carbonic anhydrase-related protein 10 {ECO:0000256|ARBA:ARBA00022137};
GN Name=ca10 {ECO:0000313|Ensembl:ENSACAP00000017111.3};
OS Anolis carolinensis (Green anole) (American chameleon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Dactyloidae; Anolis.
OX NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000017111.3, ECO:0000313|Proteomes:UP000001646};
RN [1] {ECO:0000313|Ensembl:ENSACAP00000017111.3, ECO:0000313|Proteomes:UP000001646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000017111.3,
RC ECO:0000313|Proteomes:UP000001646};
RG The Genome Sequencing Platform;
RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACAP00000017111.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Does not have a catalytic activity.
CC {ECO:0000256|ARBA:ARBA00002258}.
CC -!- SIMILARITY: Belongs to the alpha-carbonic anhydrase family.
CC {ECO:0000256|ARBA:ARBA00010718}.
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DR RefSeq; XP_003216966.1; XM_003216918.3.
DR AlphaFoldDB; G1KTU6; -.
DR STRING; 28377.ENSACAP00000017111; -.
DR Ensembl; ENSACAT00000017448.4; ENSACAP00000017111.3; ENSACAG00000017362.4.
DR GeneID; 100556498; -.
DR KEGG; acs:100556498; -.
DR CTD; 56934; -.
DR eggNOG; KOG0382; Eukaryota.
DR GeneTree; ENSGT00940000155223; -.
DR HOGENOM; CLU_039326_7_1_1; -.
DR InParanoid; G1KTU6; -.
DR OrthoDB; 49814at2759; -.
DR TreeFam; TF352926; -.
DR Proteomes; UP000001646; Chromosome 2.
DR Bgee; ENSACAG00000017362; Expressed in testis and 7 other cell types or tissues.
DR GO; GO:0004089; F:carbonate dehydratase activity; IEA:InterPro.
DR GO; GO:0016836; F:hydro-lyase activity; IBA:GO_Central.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006730; P:one-carbon metabolic process; IBA:GO_Central.
DR CDD; cd03121; alpha_CARP_X_XI_like; 1.
DR Gene3D; 3.10.200.10; Alpha carbonic anhydrase; 1.
DR InterPro; IPR041878; Alpha_CARP_X/XI.
DR InterPro; IPR001148; CA_dom.
DR InterPro; IPR036398; CA_dom_sf.
DR InterPro; IPR023561; Carbonic_anhydrase_a-class.
DR PANTHER; PTHR18952; CARBONIC ANHYDRASE; 1.
DR PANTHER; PTHR18952:SF91; CARBONIC ANHYDRASE-RELATED PROTEIN 10; 1.
DR Pfam; PF00194; Carb_anhydrase; 1.
DR SMART; SM01057; Carb_anhydrase; 1.
DR SUPFAM; SSF51069; Carbonic anhydrase; 1.
DR PROSITE; PS51144; ALPHA_CA_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001646};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..328
FT /note="Carbonic anhydrase-related protein 10"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003413631"
FT DOMAIN 31..301
FT /note="Alpha-carbonic anhydrase"
FT /evidence="ECO:0000259|PROSITE:PS51144"
SQ SEQUENCE 328 AA; 37579 MW; E1C1E7A18B9E2FB0 CRC64;
MEIVWEVLFL LQANFIVCIS AQQNSPKIHE GWWAYKEVVQ GSFVPVPSFW GLVNSAWNLC
SVGKRQSPVN IETSHMIFDP FLTPLRINTG GRKVSGTMYN TGRHVSLRLD KEHLVNISGG
PMTYSHRLEE IRLHFGSEDS QGSEHLLNGQ AFSGEVQLIH YNHELYTNVT EAAKSPNGLV
VVSIFMKVSE SSNPFLNRML NRDTITRITY KNDAYLLQGL NIEELYPETA SFITYDGSMT
IPPCYETASW ILMNKPVYIT RMQMHSLRLL SQNQPSQIFL SMSDNFRPVQ PLNNRCIRTN
INFSLQGKDC PNNRAQKLQY RVNEWLLK
//
