ID G1KU92_ANOCA Unreviewed; 234 AA.
AC G1KU92;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=STARD3 N-terminal like {ECO:0000313|Ensembl:ENSACAP00000017386.2};
GN Name=STARD3NL {ECO:0000313|Ensembl:ENSACAP00000017386.2};
OS Anolis carolinensis (Green anole) (American chameleon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Dactyloidae; Anolis.
OX NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000017386.2, ECO:0000313|Proteomes:UP000001646};
RN [1] {ECO:0000313|Ensembl:ENSACAP00000017386.2, ECO:0000313|Proteomes:UP000001646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000017386.2,
RC ECO:0000313|Proteomes:UP000001646};
RG The Genome Sequencing Platform;
RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACAP00000017386.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the STARD3 family.
CC {ECO:0000256|ARBA:ARBA00010909}.
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DR RefSeq; XP_003222380.1; XM_003222332.3.
DR AlphaFoldDB; G1KU92; -.
DR STRING; 28377.ENSACAP00000017386; -.
DR Ensembl; ENSACAT00000017727.4; ENSACAP00000017386.2; ENSACAG00000017658.4.
DR GeneID; 100555078; -.
DR KEGG; acs:100555078; -.
DR CTD; 83930; -.
DR eggNOG; KOG3845; Eukaryota.
DR GeneTree; ENSGT00940000155476; -.
DR HOGENOM; CLU_102230_0_0_1; -.
DR InParanoid; G1KU92; -.
DR OMA; HWWAVAI; -.
DR OrthoDB; 3740290at2759; -.
DR TreeFam; TF313869; -.
DR Proteomes; UP000001646; Chromosome 6.
DR Bgee; ENSACAG00000017658; Expressed in liver and 13 other cell types or tissues.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:Ensembl.
DR GO; GO:0140284; C:endoplasmic reticulum-endosome membrane contact site; IBA:GO_Central.
DR GO; GO:0031902; C:late endosome membrane; IBA:GO_Central.
DR GO; GO:0015485; F:cholesterol binding; IBA:GO_Central.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR GO; GO:0030301; P:cholesterol transport; IBA:GO_Central.
DR GO; GO:0099044; P:vesicle tethering to endoplasmic reticulum; IBA:GO_Central.
DR InterPro; IPR019498; MENTAL.
DR PANTHER; PTHR46121:SF1; STARD3 N-TERMINAL-LIKE PROTEIN; 1.
DR PANTHER; PTHR46121; STEROIDOGENIC ACUTE REGULATORY PROTEIN-LIKE; 1.
DR Pfam; PF10457; MENTAL; 1.
DR PROSITE; PS51439; MENTAL; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001646};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 55..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 96..117
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 124..146
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 152..171
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 48..219
FT /note="MENTAL"
FT /evidence="ECO:0000259|PROSITE:PS51439"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 203..234
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 234 AA; 26647 MW; 3FA30AB11EE3CA8A CRC64;
MNQLPEHRGN ALGSSLGSQP SLRDVHSINP AQLMARIESY DTREKKGISD VRRTFCLFVT
FDLLFVTLLW IIELNVNGGI ENTLKKEVLH YDYHSSYFDI FLLAVFRFKI LILAYALCRL
RHWWAIAFTT AVTSAFLLTK VIISKLLSQG PFGYVLPIIS FILAWIETWF LDFKVLPQEA
EEENRLLLVQ DASERAALLQ PGLLSDGQFY SPPESEAGSD EESEEKQDSE KAVL
//
