ID G1KVZ3_ANOCA Unreviewed; 797 AA.
AC G1KVZ3;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 2.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=Cadherin domain-containing protein {ECO:0000259|PROSITE:PS50268};
OS Anolis carolinensis (Green anole) (American chameleon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Dactyloidae; Anolis.
OX NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000018955.2, ECO:0000313|Proteomes:UP000001646};
RN [1] {ECO:0000313|Ensembl:ENSACAP00000018955.2, ECO:0000313|Proteomes:UP000001646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000018955.2,
RC ECO:0000313|Proteomes:UP000001646};
RG The Genome Sequencing Platform;
RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACAP00000018955.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G1KVZ3; -.
DR Ensembl; ENSACAT00000026364.2; ENSACAP00000018955.2; ENSACAG00000023556.2.
DR eggNOG; KOG3594; Eukaryota.
DR GeneTree; ENSGT00940000159725; -.
DR HOGENOM; CLU_006480_3_0_1; -.
DR TreeFam; TF332299; -.
DR Proteomes; UP000001646; Chromosome 4.
DR Bgee; ENSACAG00000023556; Expressed in hemipenis and 4 other cell types or tissues.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007155; P:cell adhesion; IBA:GO_Central.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 6.
DR Gene3D; 2.60.40.60; Cadherins; 6.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR032455; Cadherin_C.
DR InterPro; IPR020894; Cadherin_CS.
DR InterPro; IPR013164; Cadherin_N.
DR PANTHER; PTHR24028; CADHERIN-87A; 1.
DR PANTHER; PTHR24028:SF234; PROTOCADHERIN GAMMA-A3; 1.
DR Pfam; PF00028; Cadherin; 5.
DR Pfam; PF08266; Cadherin_2; 1.
DR Pfam; PF16492; Cadherin_C_2; 1.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 6.
DR SUPFAM; SSF49313; Cadherin-like; 6.
DR PROSITE; PS00232; CADHERIN_1; 3.
DR PROSITE; PS50268; CADHERIN_2; 6.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043}; Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001646};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 685..710
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 23..130
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 131..239
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 240..344
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 345..449
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 450..559
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 576..680
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
SQ SEQUENCE 797 AA; 87472 MW; 87C0433F29FA66DB CRC64;
GKTAIKEGKL RQVFLLFILW SAISGQIHYS IPEEMHKGSF VGNIAKDLGV DEKQLSNHGL
RIISNVGKIH YFALNANNGH LQTSERIDRE EICGRAEKCI LKFQVLNEYK LKLYGIEVEI
IDINDNAPQF PVGEQEVEIS EMSASGFRVP LMEAHDLDLG INSIQGYQLT GSGHFFLDVQ
MGENGIQHPA LLLKEPLDRE EQSVYDLILT ATDGGDPFRS GTAQIKVRVL DANDNAPIFN
QPIYEVTVKE NIPKGSTVAT VSATDLDEGL NGEVKYSLRK VTQFHSPQFL LNSTTGEITL
TGSLDYEISS LHEFEVEAKD GGGLSDRSKV IITITDLNDN APELIVNYFT SSISESSPAG
TVIAILNVQD QDSGVNGEVT CSVPNNLPFR LERSVDDFYS LVTAGTLDRE HMPTFNITIT
GTDNGIPPLS TTTVIALQVL DTNDNPPVFE KTDYTFYLVE NNHRGSLIFS LRANDPDWEE
NARITYSIIE EQTGNFPLSS YLSINSETGA VYALNSFDYE EIQEIRFLVK AQDGGSPPLS
SNVSVTLFIL DQNDNAPEIL YPSPPTDGST GIELAPRSSE PGYLITKVVA VDADSGQNAW
LSYQLTKATE PGLFTLGLHT GEIRTSRFLL EKDAFKQSLV VLVKDNGQPP LSASVTVTVV
LADNIPDTLI DLSNISVPVD HTSDLTFYLV VAVAFVSCLF LTFLLVLLAI RFHRWRKSQL
CGNGGVNFSG VPVSQFVGID GVRAFLQSYC HEVSLTSGSR KSQIFFPIGS CTNTLTPQQA
PSKPDPLKCS AFRVWEC
//
