ID   G1KYC5_ANOCA            Unreviewed;       606 AA.
AC   G1KYC5;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   29-SEP-2021, sequence version 2.
DT   27-MAR-2024, entry version 58.
DE   RecName: Full=ASD2 domain-containing protein {ECO:0000259|PROSITE:PS51307};
OS   Anolis carolinensis (Green anole) (American chameleon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC   Iguania; Dactyloidae; Anolis.
OX   NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000020797.2, ECO:0000313|Proteomes:UP000001646};
RN   [1] {ECO:0000313|Ensembl:ENSACAP00000020797.2, ECO:0000313|Proteomes:UP000001646}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000020797.2,
RC   ECO:0000313|Proteomes:UP000001646};
RG   The Genome Sequencing Platform;
RA   Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA   Lander E.S., Lindblad-Toh K.;
RT   "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL   Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSACAP00000020797.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC       {ECO:0000256|ARBA:ARBA00004245}.
CC   -!- SIMILARITY: Belongs to the shroom family.
CC       {ECO:0000256|ARBA:ARBA00006469}.
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DR   AlphaFoldDB; G1KYC5; -.
DR   Ensembl; ENSACAT00000022225.3; ENSACAP00000020797.2; ENSACAG00000000777.4.
DR   GeneTree; ENSGT00940000155212; -.
DR   InParanoid; G1KYC5; -.
DR   Proteomes; UP000001646; Chromosome 3.
DR   Bgee; ENSACAG00000000777; Expressed in hemipenis and 12 other cell types or tissues.
DR   ExpressionAtlas; G1KYC5; baseline.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR   Gene3D; 6.10.250.3120; -; 1.
DR   InterPro; IPR014799; ASD2_dom.
DR   InterPro; IPR027685; Shroom_fam.
DR   PANTHER; PTHR15012; APICAL PROTEIN/SHROOM-RELATED; 1.
DR   PANTHER; PTHR15012:SF8; PROTEIN SHROOM2; 1.
DR   Pfam; PF08687; ASD2; 1.
DR   PROSITE; PS51307; ASD2; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001646}.
FT   DOMAIN          390..606
FT                   /note="ASD2"
FT                   /evidence="ECO:0000259|PROSITE:PS51307"
FT   REGION          1..67
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          96..193
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          238..263
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          443..462
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          487..509
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          578..605
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        36..67
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        143..190
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        443..458
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   606 AA;  67371 MW;  FE754B33F16D918C CRC64;
     MSPVPRSDES NCLRPGDAAY PEGHPGERRV QQDYSVGNKW KASGRPSHTG QATVAAHGSR
     SRSGTLPSDY RYLQENVSEK SKDYNVLPLA ISELQISDES YLSPSQGKRG EGLQGDPALL
     NRKYGPVHHR PPPSKRDSNS RRQDNSSASL AASSESSLSV PNRSIQSLSS PAANVVAVSS
     PPSQTPGKVV GKYTCTELPD PPQPAASIEN TCQHLEEKPH LRSEPVLAST YRGHLKPEME
     ASRSPSPQFA PQKLTDKPPV AVQDDNPARI ERVMDNNTTV KMVPIKIVHS ESHAEKESRQ
     NLVSTIEPPA LPSGLEKDQI KTLSTSEQSY SRFCAYTRQG VEPEPENKTR LPYLQPAEAL
     GPPTKDTDVS GHTVSYVRAK EKTIEDWKSE ELAREIVGKD KSLADILDPN MKIKTTMDLM
     VGIFPKDEHL LEEAQQRRKL LLKVPSPRTS EDKKEEPPLP LGIPLTTNST YYSTSAPKAE
     LLIKMKDMQQ QQQQQQKEED SEDELDHDLS EKKQELIDSI SRKLQVLREA RETLLEDIQA
     NNLLGDEVES LVKEVCKPNE FDKFRMFIGD LDKVVNLLLS LSGRLARVEN AINNLDENAS
     AEERVR
//