ID G1LAS4_AILME Unreviewed; 185 AA.
AC G1LAS4;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Isochorismatase domain containing 2 {ECO:0000313|Ensembl:ENSAMEP00000003997.2};
GN Name=ISOC2 {ECO:0000313|Ensembl:ENSAMEP00000003997.2};
OS Ailuropoda melanoleuca (Giant panda).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda.
OX NCBI_TaxID=9646 {ECO:0000313|Ensembl:ENSAMEP00000003997.2, ECO:0000313|Proteomes:UP000008912};
RN [1] {ECO:0000313|Ensembl:ENSAMEP00000003997.2, ECO:0000313|Proteomes:UP000008912}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20010809; DOI=10.1038/nature08696;
RA Li R., Fan W., Tian G., Zhu H., He L., Cai J., Huang Q., Cai Q., Li B.,
RA Bai Y., Zhang Z., Zhang Y., Wang W., Li J., Wei F., Li H., Jian M., Li J.,
RA Zhang Z., Nielsen R., Li D., Gu W., Yang Z., Xuan Z., Ryder O.A.,
RA Leung F.C., Zhou Y., Cao J., Sun X., Fu Y., Fang X., Guo X., Wang B.,
RA Hou R., Shen F., Mu B., Ni P., Lin R., Qian W., Wang G., Yu C., Nie W.,
RA Wang J., Wu Z., Liang H., Min J., Wu Q., Cheng S., Ruan J., Wang M.,
RA Shi Z., Wen M., Liu B., Ren X., Zheng H., Dong D., Cook K., Shan G.,
RA Zhang H., Kosiol C., Xie X., Lu Z., Zheng H., Li Y., Steiner C.C.,
RA Lam T.T., Lin S., Zhang Q., Li G., Tian J., Gong T., Liu H., Zhang D.,
RA Fang L., Ye C., Zhang J., Hu W., Xu A., Ren Y., Zhang G., Bruford M.W.,
RA Li Q., Ma L., Guo Y., An N., Hu Y., Zheng Y., Shi Y., Li Z., Liu Q.,
RA Chen Y., Zhao J., Qu N., Zhao S., Tian F., Wang X., Wang H., Xu L., Liu X.,
RA Vinar T., Wang Y., Lam T.W., Yiu S.M., Liu S., Zhang H., Li D., Huang Y.,
RA Wang X., Yang G., Jiang Z., Wang J., Qin N., Li L., Li J., Bolund L.,
RA Kristiansen K., Wong G.K., Olson M., Zhang X., Li S., Yang H., Wang J.,
RA Wang J.;
RT "The sequence and de novo assembly of the giant panda genome.";
RL Nature 463:311-317(2010).
RN [2] {ECO:0000313|Ensembl:ENSAMEP00000003997.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBUNIT: Interacts with CDKN2A. {ECO:0000256|ARBA:ARBA00011687}.
CC -!- SIMILARITY: Belongs to the isochorismatase family.
CC {ECO:0000256|ARBA:ARBA00006336}.
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DR AlphaFoldDB; G1LAS4; -.
DR STRING; 9646.ENSAMEP00000003997; -.
DR Ensembl; ENSAMET00000004160.2; ENSAMEP00000003997.2; ENSAMEG00000003788.2.
DR eggNOG; KOG4044; Eukaryota.
DR GeneTree; ENSGT00390000006753; -.
DR HOGENOM; CLU_066901_0_1_1; -.
DR InParanoid; G1LAS4; -.
DR TreeFam; TF313459; -.
DR Proteomes; UP000008912; Unassembled WGS sequence.
DR Gene3D; 3.40.50.850; Isochorismatase-like; 1.
DR InterPro; IPR000868; Isochorismatase-like.
DR InterPro; IPR036380; Isochorismatase-like_sf.
DR PANTHER; PTHR14119; HYDROLASE; 1.
DR PANTHER; PTHR14119:SF3; ISOCHORISMATASE DOMAIN-CONTAINING PROTEIN 2; 1.
DR Pfam; PF00857; Isochorismatase; 1.
DR SUPFAM; SSF52499; Isochorismatase-like hydrolases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008912}.
FT DOMAIN 23..142
FT /note="Isochorismatase-like"
FT /evidence="ECO:0000259|Pfam:PF00857"
SQ SEQUENCE 185 AA; 19947 MW; EE1BD2CEAD7EE288 CRC64;
GPPRPSSLRP RSPSLRLKAL SPSLAQVARL LEVPAVLTEQ YPEGLGPTVP ELGAEGLQPL
AKTCFSMVPA VQRELDTRPQ LRSVLLCGIE TQACILNTTL DLLDRGLQVH VVVDACSSRS
QVDRLVALAR MRQSGAFLST SEGLILQLVG DAAHPQFKEI QKVIKEPAPD SGLLGLFQGQ
NPLFR
//
