ID G1LDS8_AILME Unreviewed; 863 AA.
AC G1LDS8;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=Zinc finger protein 624 {ECO:0000313|Ensembl:ENSAMEP00000005060.1};
GN Name=ZNF624 {ECO:0000313|Ensembl:ENSAMEP00000005060.1};
OS Ailuropoda melanoleuca (Giant panda).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda.
OX NCBI_TaxID=9646 {ECO:0000313|Ensembl:ENSAMEP00000005060.1, ECO:0000313|Proteomes:UP000008912};
RN [1] {ECO:0000313|Ensembl:ENSAMEP00000005060.1, ECO:0000313|Proteomes:UP000008912}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20010809; DOI=10.1038/nature08696;
RA Li R., Fan W., Tian G., Zhu H., He L., Cai J., Huang Q., Cai Q., Li B.,
RA Bai Y., Zhang Z., Zhang Y., Wang W., Li J., Wei F., Li H., Jian M., Li J.,
RA Zhang Z., Nielsen R., Li D., Gu W., Yang Z., Xuan Z., Ryder O.A.,
RA Leung F.C., Zhou Y., Cao J., Sun X., Fu Y., Fang X., Guo X., Wang B.,
RA Hou R., Shen F., Mu B., Ni P., Lin R., Qian W., Wang G., Yu C., Nie W.,
RA Wang J., Wu Z., Liang H., Min J., Wu Q., Cheng S., Ruan J., Wang M.,
RA Shi Z., Wen M., Liu B., Ren X., Zheng H., Dong D., Cook K., Shan G.,
RA Zhang H., Kosiol C., Xie X., Lu Z., Zheng H., Li Y., Steiner C.C.,
RA Lam T.T., Lin S., Zhang Q., Li G., Tian J., Gong T., Liu H., Zhang D.,
RA Fang L., Ye C., Zhang J., Hu W., Xu A., Ren Y., Zhang G., Bruford M.W.,
RA Li Q., Ma L., Guo Y., An N., Hu Y., Zheng Y., Shi Y., Li Z., Liu Q.,
RA Chen Y., Zhao J., Qu N., Zhao S., Tian F., Wang X., Wang H., Xu L., Liu X.,
RA Vinar T., Wang Y., Lam T.W., Yiu S.M., Liu S., Zhang H., Li D., Huang Y.,
RA Wang X., Yang G., Jiang Z., Wang J., Qin N., Li L., Li J., Bolund L.,
RA Kristiansen K., Wong G.K., Olson M., Zhang X., Li S., Yang H., Wang J.,
RA Wang J.;
RT "The sequence and de novo assembly of the giant panda genome.";
RL Nature 463:311-317(2010).
RN [2] {ECO:0000313|Ensembl:ENSAMEP00000005060.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G1LDS8; -.
DR STRING; 9646.ENSAMEP00000005060; -.
DR Ensembl; ENSAMET00000005268.2; ENSAMEP00000005060.1; ENSAMEG00000004801.2.
DR eggNOG; KOG1721; Eukaryota.
DR GeneTree; ENSGT00940000163207; -.
DR HOGENOM; CLU_002678_17_1_1; -.
DR OMA; GGLWKWN; -.
DR TreeFam; TF343410; -.
DR Proteomes; UP000008912; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR Gene3D; 6.10.140.140; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 21.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR23226; ZINC FINGER AND SCAN DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR23226:SF396; ZINC FINGER PROTEIN 616; 1.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF00096; zf-C2H2; 21.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 21.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 11.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 20.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 21.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000008912};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 53..124
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 274..301
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 302..329
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 330..357
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 358..385
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 386..413
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 414..441
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 442..469
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 470..497
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 498..525
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 526..553
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 554..581
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 582..609
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 610..637
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 638..665
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 666..693
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 694..721
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 722..749
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 750..777
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 778..805
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 806..833
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 834..861
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
SQ SEQUENCE 863 AA; 99564 MW; 251C9ADBBE504923 CRC64;
MPLDSTLARE GNPEEEIMAA VVFSVGPLNP EDSQPDEDLH FQAEEPELVK DSVTFKDVAI
DFTLEEWRLM DPSQRNLHKD VMLENYRNLV SLGLAVSKPD MISHLEDGKG PWVVVREMAR
APYPELETKP ATKNTVSTED ISEDASQETI IDKLTENGLW NSKMGGLWKW NERILRLQNS
QENDFNQKIV THKKIPSCQR GFRFGSILFP EAGVTTEEHH SKCQTHENFT ENLDSITDIH
LGKKICKDTE GSKAIRPTSE LTVGKKYNNK EKPYKCSTCE KSFRYRSLLI QHQRTHTKEK
PYECNECGKM FSQPSYLSQH KKIHTGEKPY KCNECGKAFI ASSSLMVHQR IHTKEKPYQC
NVCGKSFSQC ARLNQHQRIQ SGEKPYKCSE CGKAFSDKSK LARHQETHNG EKPYKCNDCG
KAFRNKSYLS VHQKTHTEEK PYKCNECGKS FKNTTIFNVH QRIHTGEKPF RCNECGKAYR
SNSSLIVHIR THTGEKPYEC NECGKAFNRI ANFTEHQRIH TGEKPYKCNE CGKAFINYSC
LTVHHRMHTG EKPYKCNECG KAFMRSSSLI VHQRIHTEEK PYLCNECGES FRIKSHLTVH
QRIHTGEKPY KCTDCERAFT KMVNLKEHQK IHTGVKPYKC YDCEKSFRTK SYLIVHQRTH
TGEKPYKCNE CEKAFTNTSQ LTVHQRRHTG EKPYKCNECG KVFTSNSGFN THQRTHTGEK
PFKCNDCGKA FSQMVHVTEH QKIHSGEKPY KCDVCGKAFR RGSYLTVHWR THTGEKPYTC
KECGKGCITL SQLTLHQRIH TGERPYKCEE CGKAFRTNSD FTVHLRMHTG EKPYKCNECG
KAFRSSSSLT VHQRIHQRET QLI
//
