ID G1LLY4_AILME Unreviewed; 615 AA.
AC G1LLY4;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=Conserved oligomeric Golgi complex subunit 8 {ECO:0000256|ARBA:ARBA00020983, ECO:0000256|PIRNR:PIRNR015415};
DE Short=COG complex subunit 8 {ECO:0000256|PIRNR:PIRNR015415};
DE AltName: Full=Component of oligomeric Golgi complex 8 {ECO:0000256|ARBA:ARBA00031347, ECO:0000256|PIRNR:PIRNR015415};
GN Name=COG8 {ECO:0000313|Ensembl:ENSAMEP00000007961.2};
OS Ailuropoda melanoleuca (Giant panda).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda.
OX NCBI_TaxID=9646 {ECO:0000313|Ensembl:ENSAMEP00000007961.2, ECO:0000313|Proteomes:UP000008912};
RN [1] {ECO:0000313|Ensembl:ENSAMEP00000007961.2, ECO:0000313|Proteomes:UP000008912}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20010809; DOI=10.1038/nature08696;
RA Li R., Fan W., Tian G., Zhu H., He L., Cai J., Huang Q., Cai Q., Li B.,
RA Bai Y., Zhang Z., Zhang Y., Wang W., Li J., Wei F., Li H., Jian M., Li J.,
RA Zhang Z., Nielsen R., Li D., Gu W., Yang Z., Xuan Z., Ryder O.A.,
RA Leung F.C., Zhou Y., Cao J., Sun X., Fu Y., Fang X., Guo X., Wang B.,
RA Hou R., Shen F., Mu B., Ni P., Lin R., Qian W., Wang G., Yu C., Nie W.,
RA Wang J., Wu Z., Liang H., Min J., Wu Q., Cheng S., Ruan J., Wang M.,
RA Shi Z., Wen M., Liu B., Ren X., Zheng H., Dong D., Cook K., Shan G.,
RA Zhang H., Kosiol C., Xie X., Lu Z., Zheng H., Li Y., Steiner C.C.,
RA Lam T.T., Lin S., Zhang Q., Li G., Tian J., Gong T., Liu H., Zhang D.,
RA Fang L., Ye C., Zhang J., Hu W., Xu A., Ren Y., Zhang G., Bruford M.W.,
RA Li Q., Ma L., Guo Y., An N., Hu Y., Zheng Y., Shi Y., Li Z., Liu Q.,
RA Chen Y., Zhao J., Qu N., Zhao S., Tian F., Wang X., Wang H., Xu L., Liu X.,
RA Vinar T., Wang Y., Lam T.W., Yiu S.M., Liu S., Zhang H., Li D., Huang Y.,
RA Wang X., Yang G., Jiang Z., Wang J., Qin N., Li L., Li J., Bolund L.,
RA Kristiansen K., Wong G.K., Olson M., Zhang X., Li S., Yang H., Wang J.,
RA Wang J.;
RT "The sequence and de novo assembly of the giant panda genome.";
RL Nature 463:311-317(2010).
RN [2] {ECO:0000313|Ensembl:ENSAMEP00000007961.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBUNIT: Component of the conserved oligomeric Golgi complex which is
CC composed of eight different subunits and is required for normal Golgi
CC morphology and localization. {ECO:0000256|PIRNR:PIRNR015415}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000256|ARBA:ARBA00004395, ECO:0000256|PIRNR:PIRNR015415};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004395,
CC ECO:0000256|PIRNR:PIRNR015415}. Membrane
CC {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the COG8 family. {ECO:0000256|ARBA:ARBA00006419,
CC ECO:0000256|PIRNR:PIRNR015415}.
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DR AlphaFoldDB; G1LLY4; -.
DR STRING; 9646.ENSAMEP00000007961; -.
DR Ensembl; ENSAMET00000008293.2; ENSAMEP00000007961.2; ENSAMEG00000007560.2.
DR eggNOG; KOG2069; Eukaryota.
DR GeneTree; ENSGT00390000015893; -.
DR HOGENOM; CLU_017968_0_0_1; -.
DR InParanoid; G1LLY4; -.
DR TreeFam; TF315000; -.
DR Proteomes; UP000008912; Unassembled WGS sequence.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0017119; C:Golgi transport complex; IEA:UniProtKB-UniRule.
DR GO; GO:0070085; P:glycosylation; IEA:Ensembl.
DR GO; GO:0007030; P:Golgi organization; IEA:Ensembl.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-UniRule.
DR GO; GO:0000301; P:retrograde transport, vesicle recycling within Golgi; IEA:Ensembl.
DR InterPro; IPR007255; COG8.
DR InterPro; IPR016632; COG8_Metazoal_Plant.
DR InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR PANTHER; PTHR21311; CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 8; 1.
DR PANTHER; PTHR21311:SF0; CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 8; 1.
DR Pfam; PF04124; Dor1; 1.
DR PIRSF; PIRSF015415; COG8; 1.
DR SUPFAM; SSF74788; Cullin repeat-like; 1.
PE 3: Inferred from homology;
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034,
KW ECO:0000256|PIRNR:PIRNR015415};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR015415};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|PIRNR:PIRNR015415};
KW Reference proteome {ECO:0000313|Proteomes:UP000008912};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR015415}.
FT REGION 575..615
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 615 AA; 68803 MW; B358967FE721428B CRC64;
MAATTASATA TATAAALGEV EDEGLLASLF RDRFPEAQWR ERPDVGRYLR ELSGSGLERL
RREPERLAEE RAQLLQQTRD LAFANYKTFI RGAECTERIH RLFGDVEASL GRLLDRLPSF
QQSCRNFVKE AEEISSNRRM NTLTLNRHTE ILEILEIPQL MDTCVRNSYY EEALELAAYV
RRLERKYSSI PVIQGIVNEV RQSMQLMLSQ LIQQLRTNIQ LPACLRVISF LRCMDVFTEA
ELRVKFLQAR DAWLRSILTA IPNDDPYFHI TKTIEACRVH LFDIITQYRA IFSDEDPLLP
PATGEHTMNE SAIFHGWVLQ RVSQFLQVLE TDLHRGIGGR LDSLLGQCMY FGLSFSRVGV
DFRGQLAPVF QRVAISTFQK AIQEAVEKFQ DEMNSYTLIS APAILGSSNL PAAVPVTQPG
TLQPPMVLLD FPPLACFLNN ILVAFNDLRL CCPVALAQDV TRALEDALAK VTKTILAFHR
AEEAAFSSGE QELFVQFCTV FLEDLVPYLN RCLQVLFPPA QIAQTLGIPP TQLSKYGNLG
HVNIGLVQEP LAFLLPKREL VLCLDEKELV PELAAPAPAA EESSLEPVAA ARPEDAQDQA
DSASEPQAEV PGADT
//
