ID G1LXT9_AILME Unreviewed; 1413 AA.
AC G1LXT9;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=SET domain containing 5 {ECO:0000313|Ensembl:ENSAMEP00000011894.2};
GN Name=SETD5 {ECO:0000313|Ensembl:ENSAMEP00000011894.2};
OS Ailuropoda melanoleuca (Giant panda).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda.
OX NCBI_TaxID=9646 {ECO:0000313|Ensembl:ENSAMEP00000011894.2, ECO:0000313|Proteomes:UP000008912};
RN [1] {ECO:0000313|Ensembl:ENSAMEP00000011894.2, ECO:0000313|Proteomes:UP000008912}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20010809; DOI=10.1038/nature08696;
RA Li R., Fan W., Tian G., Zhu H., He L., Cai J., Huang Q., Cai Q., Li B.,
RA Bai Y., Zhang Z., Zhang Y., Wang W., Li J., Wei F., Li H., Jian M., Li J.,
RA Zhang Z., Nielsen R., Li D., Gu W., Yang Z., Xuan Z., Ryder O.A.,
RA Leung F.C., Zhou Y., Cao J., Sun X., Fu Y., Fang X., Guo X., Wang B.,
RA Hou R., Shen F., Mu B., Ni P., Lin R., Qian W., Wang G., Yu C., Nie W.,
RA Wang J., Wu Z., Liang H., Min J., Wu Q., Cheng S., Ruan J., Wang M.,
RA Shi Z., Wen M., Liu B., Ren X., Zheng H., Dong D., Cook K., Shan G.,
RA Zhang H., Kosiol C., Xie X., Lu Z., Zheng H., Li Y., Steiner C.C.,
RA Lam T.T., Lin S., Zhang Q., Li G., Tian J., Gong T., Liu H., Zhang D.,
RA Fang L., Ye C., Zhang J., Hu W., Xu A., Ren Y., Zhang G., Bruford M.W.,
RA Li Q., Ma L., Guo Y., An N., Hu Y., Zheng Y., Shi Y., Li Z., Liu Q.,
RA Chen Y., Zhao J., Qu N., Zhao S., Tian F., Wang X., Wang H., Xu L., Liu X.,
RA Vinar T., Wang Y., Lam T.W., Yiu S.M., Liu S., Zhang H., Li D., Huang Y.,
RA Wang X., Yang G., Jiang Z., Wang J., Qin N., Li L., Li J., Bolund L.,
RA Kristiansen K., Wong G.K., Olson M., Zhang X., Li S., Yang H., Wang J.,
RA Wang J.;
RT "The sequence and de novo assembly of the giant panda genome.";
RL Nature 463:311-317(2010).
RN [2] {ECO:0000313|Ensembl:ENSAMEP00000011894.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR STRING; 9646.ENSAMEP00000011894; -.
DR Ensembl; ENSAMET00000012398.2; ENSAMEP00000011894.2; ENSAMEG00000011307.2.
DR eggNOG; KOG1844; Eukaryota.
DR GeneTree; ENSGT00940000157446; -.
DR HOGENOM; CLU_002373_0_0_1; -.
DR OrthoDB; 2919208at2759; -.
DR TreeFam; TF106417; -.
DR Proteomes; UP000008912; Unassembled WGS sequence.
DR CDD; cd19181; SET_SETD5; 1.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR InterPro; IPR044433; SETD5_SET.
DR PANTHER; PTHR46462:SF1; HISTONE-LYSINE N-METHYLTRANSFERASE SETD5; 1.
DR PANTHER; PTHR46462; UPSET, ISOFORM A; 1.
DR Pfam; PF00856; SET; 1.
DR SMART; SM00317; SET; 1.
DR SUPFAM; SSF82199; SET domain; 1.
DR PROSITE; PS50280; SET; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008912};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..1413
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5030171152"
FT DOMAIN 244..365
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT REGION 126..177
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 390..651
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 766..796
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 823..855
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 906..941
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1009..1200
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1214..1413
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 127..142
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 143..162
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 163..177
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 394..408
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 412..427
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 432..446
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 472..512
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 513..528
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 545..567
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 594..651
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 825..847
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1039..1054
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1056..1139
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1214..1388
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1413 AA; 154996 MW; 79FA1D07FC36A08D CRC64;
MSQLTLAFCF ITFLVEAKKQ RTIIPRSDLN GLPSPVEERC GDSPNSEGET VPTWCPCGLS
QDGFLLNCDK CRGMSRGKVI RLHRRKQDNI SGGDSSATES WDEELSPSTV LYTATQHTPT
SITLTVRRTK PKKRKKSPEK GRAAAKTKKI KAFREGSRKS LRMKNSPSEA QNLDENTTEG
WENRIRLWTD QYEEAFTNQY SADVQNALEQ HLHSSKEFVG KPAILDTINK TELACNNTVI
GSQMQLQLGR VTRVQKHRKI LRAARDLALD TLIIEYRGKV MLRQQFEVNG HFFKKPYPFV
LFYSKFNGVE MCVDARTFGN DARFIRRSCT PNAEVRHMIA DGMIHLCIYA VSAITKDAEV
TIAFDYEYSN CNYKVDCACH KGNRNCPIQK RNPNAAEPPL PPPPSLPTIG AETRRRKARR
KELEMEQQNE APEEDNSQQP EQVPEKATVS SDHEEIDNPE EKAEEEKEEV TDDQENPAHS
RRTREDRKVE AIMHAFENLE KRKKRRDQPL EQSSSDIEIT TTTSEVPVGE EAKTEAPEPE
VSNPASNMAI PSTPQSVGVN TRRSSQAGDV AAEKPVPKPP PAKPSRPRPK SRISRYRTSS
AQRLKRQKQA IAQQAELSQA ALEDGGNNSS VTPTEAGNID SSGENRQLMG SDPTVVSVTG
SHVNRAAPKY PKTKKYLVTE WLNDKAEKQE CPVECPLRIT TDPTVLATTL NMLPGLIHSP
LICTTPKHYI RFGSPFIPER RRRPLLPDGT FSSCKKRWIK QALEEGMTQT SSVPQETRTQ
HLYQSNENSN SSSICKDNAD LLSPLKKWKS RYLMEQNVTK LLRPLSPVTP PPPNPGSKSP
PLTTPGPSHP EEECRNGYSL MFSPITSLTT ASRCNTPLQF ELCHRKDLDL TKVGYLDSNT
NSCADRPSLI NSGPSDLAPH PSVGPPSETG FPSRSGDGHQ TLARNSDQAF RTEFNLMYAY
SPLNAMPRAD GLYRGSPLVG DRKPLHLDGG YCSPAEGFPS RYEHSFMKDL SRGSVSPGGE
RACEGVPSAP QNPPQRKKVS LLEYRKRKQE AKENSGGGGD SAQSKIKSAG AGQGSSNSLS
DTGAHGVQGS STRTPSSPHK KFSPSHSSMS HMEAVSPSDS RGTSSHCRPQ ENISSRWMVP
TSVERLREGG SIPKVLRSSV RVAQKGEPSP TWESNITEKD SDPTDGEGPE TLSSALSKGA
AVYSPSRYSY QLLQCDSPRT ESQSLLQQSS SPFRGHPTQS PGYSYRTTAL RPGNPPSHGS
SESSLSSTSY SSPAHPVSTD SLAPFTGTPG YYSSQPHSGN STGSNLPRRS CPSSAASPTP
QGPSDSPTSD SVSQSSTGTL SSTSFPQNSR SSLPSDLRTI SLPSAGQSTA YQASRVSAVS
NSQHYPHRGS GGVHQYRLQP LQGSGVKTQT GLS
//
