ID G1M2M1_AILME Unreviewed; 1017 AA.
AC G1M2M1;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=PHD finger protein 20-like protein 1 {ECO:0000256|ARBA:ARBA00014842};
GN Name=PHF20L1 {ECO:0000313|Ensembl:ENSAMEP00000013582.2};
OS Ailuropoda melanoleuca (Giant panda).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda.
OX NCBI_TaxID=9646 {ECO:0000313|Ensembl:ENSAMEP00000013582.2, ECO:0000313|Proteomes:UP000008912};
RN [1] {ECO:0000313|Ensembl:ENSAMEP00000013582.2, ECO:0000313|Proteomes:UP000008912}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20010809; DOI=10.1038/nature08696;
RA Li R., Fan W., Tian G., Zhu H., He L., Cai J., Huang Q., Cai Q., Li B.,
RA Bai Y., Zhang Z., Zhang Y., Wang W., Li J., Wei F., Li H., Jian M., Li J.,
RA Zhang Z., Nielsen R., Li D., Gu W., Yang Z., Xuan Z., Ryder O.A.,
RA Leung F.C., Zhou Y., Cao J., Sun X., Fu Y., Fang X., Guo X., Wang B.,
RA Hou R., Shen F., Mu B., Ni P., Lin R., Qian W., Wang G., Yu C., Nie W.,
RA Wang J., Wu Z., Liang H., Min J., Wu Q., Cheng S., Ruan J., Wang M.,
RA Shi Z., Wen M., Liu B., Ren X., Zheng H., Dong D., Cook K., Shan G.,
RA Zhang H., Kosiol C., Xie X., Lu Z., Zheng H., Li Y., Steiner C.C.,
RA Lam T.T., Lin S., Zhang Q., Li G., Tian J., Gong T., Liu H., Zhang D.,
RA Fang L., Ye C., Zhang J., Hu W., Xu A., Ren Y., Zhang G., Bruford M.W.,
RA Li Q., Ma L., Guo Y., An N., Hu Y., Zheng Y., Shi Y., Li Z., Liu Q.,
RA Chen Y., Zhao J., Qu N., Zhao S., Tian F., Wang X., Wang H., Xu L., Liu X.,
RA Vinar T., Wang Y., Lam T.W., Yiu S.M., Liu S., Zhang H., Li D., Huang Y.,
RA Wang X., Yang G., Jiang Z., Wang J., Qin N., Li L., Li J., Bolund L.,
RA Kristiansen K., Wong G.K., Olson M., Zhang X., Li S., Yang H., Wang J.,
RA Wang J.;
RT "The sequence and de novo assembly of the giant panda genome.";
RL Nature 463:311-317(2010).
RN [2] {ECO:0000313|Ensembl:ENSAMEP00000013582.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_002917661.1; XM_002917615.3.
DR AlphaFoldDB; G1M2M1; -.
DR Ensembl; ENSAMET00000014149.2; ENSAMEP00000013582.2; ENSAMEG00000012878.2.
DR GeneID; 100473104; -.
DR KEGG; aml:100473104; -.
DR CTD; 51105; -.
DR GeneTree; ENSGT00940000156215; -.
DR InParanoid; G1M2M1; -.
DR Proteomes; UP000008912; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0140034; F:methylation-dependent protein binding; IEA:Ensembl.
DR GO; GO:0032435; P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR CDD; cd20104; MBT_PHF20L1-like; 1.
DR CDD; cd15633; PHD_PHF20L1; 1.
DR CDD; cd20454; Tudor_PHF20L1; 1.
DR Gene3D; 2.30.30.140; -; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR014002; Agenet_dom_plant.
DR InterPro; IPR040477; KDM4-like_Tudor.
DR InterPro; IPR043449; PHF20-like.
DR InterPro; IPR002999; Tudor.
DR InterPro; IPR047405; Tudor_PHF20L1.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR15856:SF26; PHD FINGER PROTEIN 20-LIKE PROTEIN 1; 1.
DR PANTHER; PTHR15856; PHD FINGER PROTEIN 20-RELATED; 1.
DR Pfam; PF16660; PHD20L1_u1; 1.
DR Pfam; PF20826; PHD_5; 1.
DR Pfam; PF18104; Tudor_2; 1.
DR SMART; SM00743; Agenet; 2.
DR SMART; SM00333; TUDOR; 2.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 2.
DR PROSITE; PS01359; ZF_PHD_1; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000008912};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 11..73
FT /note="Agenet"
FT /evidence="ECO:0000259|SMART:SM00743"
FT DOMAIN 11..71
FT /note="Tudor"
FT /evidence="ECO:0000259|SMART:SM00333"
FT DOMAIN 85..141
FT /note="Agenet"
FT /evidence="ECO:0000259|SMART:SM00743"
FT DOMAIN 85..141
FT /note="Tudor"
FT /evidence="ECO:0000259|SMART:SM00333"
FT REGION 183..246
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 306..374
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 386..456
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 480..583
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 864..921
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 195..212
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 219..234
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 309..344
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 437..454
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 529..559
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 560..577
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 892..917
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1017 AA; 114952 MW; EC7CDA53F8DC7892 CRC64;
MSKKPPNRPG ITFEIGARLE ALDYLQKWYP SRIEKIDYEE GKMLVHFERW SHRYDEWIYW
DSNRLRPLER PALRKEGLKD EEDFFDFKAG EEVLARWTDC RYYPAKIEAI NKEGTFTVQF
YDGVIRCLKR MHIKAMPEDA KGQVKSQHPL SWCCPIDPAG SCNQSMGSED WIALVKAAAA
AAAKNKTGSK PRTSANSNKE KDERKWFKVP SKKEETSTSI ASAEVEKKED LPTSSETFGL
HVENVPKMVF PQPESTLSNK RKNNQGNSFQ AKRARLNKIT GLLASKAVGV DGADRKEDCT
ETAPMLEQAI SPKPQSQKKN EADISSSANT QKPALLSSTL SSGKARSKKC KHESGDSSGC
IKPPKSPLSP ELIQVEDLTL VSQLSSSVIN KTSSPQPVNP PRPFKHSERR RRSQRLATLP
MPDDSVEKVS PPSPATDGKV FSISSQTQQE SSVPEVPDVA HLSLEKLGPC LPLDLSRGSE
VSAPLAPDPA YHNECPRAEK EDTQMLTNPS SKAIAEGRGA PTASGISKTE KKVKLEEKSS
TAFGKRKEKD KERKEKKDKD HYKPKQKKKK KKKKKSKQHD YSDYEDSSLE FLERCSSPLT
RSSGSSLALR SMFTEKNTTY QYPRAILSVD LSGENLSDVE FLDDSSTESL LLSGDEYNQD
FDSTNFEESQ DEDDALNEIV RCICEMDEEN GFMIQCEECL CWQHSVCMGL LEESIPEQYI
CYICRDPPGQ RWSAKYRYDK DWLDNGRMCG LSFLKENYSH LNAKKIVSTH HLLADVYGVT
EVLHGLQLKI GILKNKHHPD LRLWACSGTR KDQDQGIAGV EKKVTVQDTV NVEEKKYHVQ
NHKEPPRLPL KMEGTYITSE HSYQKPQNFG QDCKSLADPG SSDDDDVSSF EEEQEFHTKD
KNRSQYSVKE DGMPEKNPAE RNTVFIYNDK KGSEDPGDSH LQWQLNLLTH IENVQNEVTS
RMDLIEKEVD VLESWLDFTG ELEPPDPLAR LPQLKRHIKQ LLIDMGKVQQ IATLCSV
//
