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Database: UniProt
Entry: G1M5A5_AILME
LinkDB: G1M5A5_AILME
Original site: G1M5A5_AILME 
ID   G1M5A5_AILME            Unreviewed;       577 AA.
AC   G1M5A5;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   20-JUN-2018, entry version 40.
DE   SubName: Full=SH2B adaptor protein 3 {ECO:0000313|Ensembl:ENSAMEP00000014522};
GN   Name=SH2B3 {ECO:0000313|Ensembl:ENSAMEP00000014522};
OS   Ailuropoda melanoleuca (Giant panda).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae;
OC   Ailuropoda.
OX   NCBI_TaxID=9646 {ECO:0000313|Ensembl:ENSAMEP00000014522, ECO:0000313|Proteomes:UP000008912};
RN   [1] {ECO:0000313|Ensembl:ENSAMEP00000014522}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=20010809; DOI=10.1038/nature08696;
RA   Li R., Fan W., Tian G., Zhu H., He L., Cai J., Huang Q., Cai Q.,
RA   Li B., Bai Y., Zhang Z., Zhang Y., Wang W., Li J., Wei F., Li H.,
RA   Jian M., Li J., Zhang Z., Nielsen R., Li D., Gu W., Yang Z., Xuan Z.,
RA   Ryder O.A., Leung F.C., Zhou Y., Cao J., Sun X., Fu Y., Fang X.,
RA   Guo X., Wang B., Hou R., Shen F., Mu B., Ni P., Lin R., Qian W.,
RA   Wang G., Yu C., Nie W., Wang J., Wu Z., Liang H., Min J., Wu Q.,
RA   Cheng S., Ruan J., Wang M., Shi Z., Wen M., Liu B., Ren X., Zheng H.,
RA   Dong D., Cook K., Shan G., Zhang H., Kosiol C., Xie X., Lu Z.,
RA   Zheng H., Li Y., Steiner C.C., Lam T.T., Lin S., Zhang Q., Li G.,
RA   Tian J., Gong T., Liu H., Zhang D., Fang L., Ye C., Zhang J., Hu W.,
RA   Xu A., Ren Y., Zhang G., Bruford M.W., Li Q., Ma L., Guo Y., An N.,
RA   Hu Y., Zheng Y., Shi Y., Li Z., Liu Q., Chen Y., Zhao J., Qu N.,
RA   Zhao S., Tian F., Wang X., Wang H., Xu L., Liu X., Vinar T., Wang Y.,
RA   Lam T.W., Yiu S.M., Liu S., Zhang H., Li D., Huang Y., Wang X.,
RA   Yang G., Jiang Z., Wang J., Qin N., Li L., Li J., Bolund L.,
RA   Kristiansen K., Wong G.K., Olson M., Zhang X., Li S., Yang H.,
RA   Wang J., Wang J.;
RT   "The sequence and de novo assembly of the giant panda genome.";
RL   Nature 463:311-317(2010).
RN   [2] {ECO:0000313|Ensembl:ENSAMEP00000014522}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2011) to UniProtKB.
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DR   EMBL; ACTA01048592; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ACTA01056592; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 9646.ENSAMEP00000014522; -.
DR   Ensembl; ENSAMET00000015128; ENSAMEP00000014522; ENSAMEG00000013785.
DR   eggNOG; ENOG410IFCS; Eukaryota.
DR   eggNOG; ENOG410YMBM; LUCA.
DR   GeneTree; ENSGT00530000063355; -.
DR   InParanoid; G1M5A5; -.
DR   OrthoDB; EOG091G04RI; -.
DR   TreeFam; TF323184; -.
DR   Proteomes; UP000008912; Unassembled WGS sequence.
DR   GO; GO:0005622; C:intracellular; IEA:GOC.
DR   GO; GO:0035591; F:signaling adaptor activity; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:Ensembl.
DR   GO; GO:0035162; P:embryonic hemopoiesis; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:Ensembl.
DR   CDD; cd10412; SH2_SH2B3; 1.
DR   Gene3D; 2.30.29.30; -; 1.
DR   Gene3D; 3.30.505.10; -; 1.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR015012; Phe_ZIP.
DR   InterPro; IPR036290; Phe_ZIP_sf.
DR   InterPro; IPR000980; SH2.
DR   InterPro; IPR036860; SH2_dom_sf.
DR   InterPro; IPR030523; SH2B.
DR   InterPro; IPR030522; SH2B3.
DR   InterPro; IPR035059; SH2B3_SH2.
DR   PANTHER; PTHR10872; PTHR10872; 1.
DR   PANTHER; PTHR10872:SF1; PTHR10872:SF1; 1.
DR   Pfam; PF08916; Phe_ZIP; 1.
DR   Pfam; PF00017; SH2; 1.
DR   PRINTS; PR00401; SH2DOMAIN.
DR   SMART; SM00252; SH2; 1.
DR   SUPFAM; SSF109805; SSF109805; 1.
DR   SUPFAM; SSF55550; SSF55550; 1.
DR   PROSITE; PS50001; SH2; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000008912};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008912};
KW   SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191}.
FT   DOMAIN      374    472       SH2. {ECO:0000259|PROSITE:PS50001}.
SQ   SEQUENCE   577 AA;  62457 MW;  F6BB345C77D5DE26 CRC64;
     MNGPTLQPSS ASSASSPSSS AAASSSSSSP RGWSEFCELH AVAAARELAR QYWLFAREHP
     HHAPLRAELV SLQFTDLFQR FLAKQMPCGR GHGYEPQGAP RGPEAGARAP SVGKTASATG
     LPRPRTSSLT FPPNCSFFSI HSCRRPCSLR SGAGSLPGAP AAPRTPEAVV ASTSSESSFF
     EGRQWVWVVT SPLSSAALPH PRLLTEAVSS QPQLFPPSAA SAAAWGHSRS PRCWTLSPDS
     RGRVVALLDL IKSSKPKLQA ACSNIQEVRR CTRLEMPDNL YTFVLKVKDR TDIIFEVGDE
     QQLNSWMAEL RECTGHGLES TDPEMHIPSA LEPGTGTSNS PGGSTDSLNQ GASPGGLLDP
     ACQKTDHFLS CYPWFHGPIS RVKAAQLVQL QGPDAHGVFL VRQSETRRGE YVLTFNFQGI
     AKHLRLSLTE RGQCRVQHLH FPSVVDMLHH FQRSPIPLEC GAACDVRLSS YVVVVSQPPG
     SSNTVLFPFS LAHWDSELGL PHLSSSGCPR GLGPEGLPGR SSPPEQIFHL VPSPEELANS
     LRHLEPEPAS RARDSDYEMD STSRSHLRAI DNQYTPL
//
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