ID G1M9H3_AILME Unreviewed; 223 AA.
AC G1M9H3;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Epididymal sperm binding protein 1 {ECO:0000313|Ensembl:ENSAMEP00000015993.2};
GN Name=ELSPBP1 {ECO:0000313|Ensembl:ENSAMEP00000015993.2};
OS Ailuropoda melanoleuca (Giant panda).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda.
OX NCBI_TaxID=9646 {ECO:0000313|Ensembl:ENSAMEP00000015993.2, ECO:0000313|Proteomes:UP000008912};
RN [1] {ECO:0000313|Ensembl:ENSAMEP00000015993.2, ECO:0000313|Proteomes:UP000008912}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20010809; DOI=10.1038/nature08696;
RA Li R., Fan W., Tian G., Zhu H., He L., Cai J., Huang Q., Cai Q., Li B.,
RA Bai Y., Zhang Z., Zhang Y., Wang W., Li J., Wei F., Li H., Jian M., Li J.,
RA Zhang Z., Nielsen R., Li D., Gu W., Yang Z., Xuan Z., Ryder O.A.,
RA Leung F.C., Zhou Y., Cao J., Sun X., Fu Y., Fang X., Guo X., Wang B.,
RA Hou R., Shen F., Mu B., Ni P., Lin R., Qian W., Wang G., Yu C., Nie W.,
RA Wang J., Wu Z., Liang H., Min J., Wu Q., Cheng S., Ruan J., Wang M.,
RA Shi Z., Wen M., Liu B., Ren X., Zheng H., Dong D., Cook K., Shan G.,
RA Zhang H., Kosiol C., Xie X., Lu Z., Zheng H., Li Y., Steiner C.C.,
RA Lam T.T., Lin S., Zhang Q., Li G., Tian J., Gong T., Liu H., Zhang D.,
RA Fang L., Ye C., Zhang J., Hu W., Xu A., Ren Y., Zhang G., Bruford M.W.,
RA Li Q., Ma L., Guo Y., An N., Hu Y., Zheng Y., Shi Y., Li Z., Liu Q.,
RA Chen Y., Zhao J., Qu N., Zhao S., Tian F., Wang X., Wang H., Xu L., Liu X.,
RA Vinar T., Wang Y., Lam T.W., Yiu S.M., Liu S., Zhang H., Li D., Huang Y.,
RA Wang X., Yang G., Jiang Z., Wang J., Qin N., Li L., Li J., Bolund L.,
RA Kristiansen K., Wong G.K., Olson M., Zhang X., Li S., Yang H., Wang J.,
RA Wang J.;
RT "The sequence and de novo assembly of the giant panda genome.";
RL Nature 463:311-317(2010).
RN [2] {ECO:0000313|Ensembl:ENSAMEP00000015993.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the seminal plasma protein family.
CC {ECO:0000256|ARBA:ARBA00010011}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00479}.
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DR RefSeq; XP_011221573.1; XM_011223271.2.
DR AlphaFoldDB; G1M9H3; -.
DR STRING; 9646.ENSAMEP00000015993; -.
DR Ensembl; ENSAMET00000016660.2; ENSAMEP00000015993.2; ENSAMEG00000015177.2.
DR GeneID; 100474629; -.
DR KEGG; aml:100474629; -.
DR CTD; 64100; -.
DR eggNOG; KOG1565; Eukaryota.
DR GeneTree; ENSGT00940000162766; -.
DR HOGENOM; CLU_115665_0_0_1; -.
DR InParanoid; G1M9H3; -.
DR TreeFam; TF343543; -.
DR Proteomes; UP000008912; Unassembled WGS sequence.
DR GO; GO:0007338; P:single fertilization; IEA:UniProtKB-KW.
DR CDD; cd00062; FN2; 3.
DR Gene3D; 2.10.10.10; Fibronectin, type II, collagen-binding; 4.
DR InterPro; IPR000562; FN_type2_dom.
DR InterPro; IPR036943; FN_type2_sf.
DR InterPro; IPR013806; Kringle-like.
DR PANTHER; PTHR22918:SF1; FEMALE STERILE (1) M3; 1.
DR PANTHER; PTHR22918; SEMINAL PLASMA PROTEIN; 1.
DR Pfam; PF00040; fn2; 4.
DR PRINTS; PR00013; FNTYPEII.
DR SMART; SM00059; FN2; 4.
DR SUPFAM; SSF57440; Kringle-like; 4.
DR PROSITE; PS00023; FN2_1; 2.
DR PROSITE; PS51092; FN2_2; 4.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00479}; Fertilization {ECO:0000256|ARBA:ARBA00023279};
KW Reference proteome {ECO:0000313|Proteomes:UP000008912};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..223
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5030171455"
FT DOMAIN 24..68
FT /note="Fibronectin type-II"
FT /evidence="ECO:0000259|PROSITE:PS51092"
FT DOMAIN 69..117
FT /note="Fibronectin type-II"
FT /evidence="ECO:0000259|PROSITE:PS51092"
FT DOMAIN 124..170
FT /note="Fibronectin type-II"
FT /evidence="ECO:0000259|PROSITE:PS51092"
FT DOMAIN 177..223
FT /note="Fibronectin type-II"
FT /evidence="ECO:0000259|PROSITE:PS51092"
FT DISULFID 74..100
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00479"
FT DISULFID 88..115
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00479"
FT DISULFID 182..208
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00479"
FT DISULFID 196..223
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00479"
SQ SEQUENCE 223 AA; 26218 MW; E2819C64383F25D0 CRC64;
MNPWSSYLLG WTAFLLYSYE TSGNQKDSCV FPFIYKGSSY FSCIKTNSFS PWCATRAIYD
GQWKYCMVDD YPRCIFPFIY RGRSHNSCII EGSFLGRLWC SVTSNFDEKQ QWKYCETNEY
GGNSFSKPCI FPSIYRNSTI FECIEDENNK LWCPTTESMD EDGKWSLCAD TRISSLVPGL
PCHFPFNYKN KNYFKCTDKG TKQNLTWCAT SYNYDRDRTW VYC
//
