ID G1MBM9_AILME Unreviewed; 3111 AA.
AC G1MBM9;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 12-AUG-2020, entry version 48.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSAMEP00000016757};
GN Name=CENPF {ECO:0000313|Ensembl:ENSAMEP00000016757};
OS Ailuropoda melanoleuca (Giant panda).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda.
OX NCBI_TaxID=9646 {ECO:0000313|Ensembl:ENSAMEP00000016757, ECO:0000313|Proteomes:UP000008912};
RN [1] {ECO:0000313|Ensembl:ENSAMEP00000016757, ECO:0000313|Proteomes:UP000008912}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20010809; DOI=10.1038/nature08696;
RA Li R., Fan W., Tian G., Zhu H., He L., Cai J., Huang Q., Cai Q., Li B.,
RA Bai Y., Zhang Z., Zhang Y., Wang W., Li J., Wei F., Li H., Jian M., Li J.,
RA Zhang Z., Nielsen R., Li D., Gu W., Yang Z., Xuan Z., Ryder O.A.,
RA Leung F.C., Zhou Y., Cao J., Sun X., Fu Y., Fang X., Guo X., Wang B.,
RA Hou R., Shen F., Mu B., Ni P., Lin R., Qian W., Wang G., Yu C., Nie W.,
RA Wang J., Wu Z., Liang H., Min J., Wu Q., Cheng S., Ruan J., Wang M.,
RA Shi Z., Wen M., Liu B., Ren X., Zheng H., Dong D., Cook K., Shan G.,
RA Zhang H., Kosiol C., Xie X., Lu Z., Zheng H., Li Y., Steiner C.C.,
RA Lam T.T., Lin S., Zhang Q., Li G., Tian J., Gong T., Liu H., Zhang D.,
RA Fang L., Ye C., Zhang J., Hu W., Xu A., Ren Y., Zhang G., Bruford M.W.,
RA Li Q., Ma L., Guo Y., An N., Hu Y., Zheng Y., Shi Y., Li Z., Liu Q.,
RA Chen Y., Zhao J., Qu N., Zhao S., Tian F., Wang X., Wang H., Xu L., Liu X.,
RA Vinar T., Wang Y., Lam T.W., Yiu S.M., Liu S., Zhang H., Li D., Huang Y.,
RA Wang X., Yang G., Jiang Z., Wang J., Qin N., Li L., Li J., Bolund L.,
RA Kristiansen K., Wong G.K., Olson M., Zhang X., Li S., Yang H., Wang J.,
RA Wang J.;
RT "The sequence and de novo assembly of the giant panda genome.";
RL Nature 463:311-317(2010).
RN [2] {ECO:0000313|Ensembl:ENSAMEP00000016757}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2011) to UniProtKB.
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DR EMBL; ACTA01099679; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ACTA01107679; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ACTA01115679; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ACTA01123679; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ACTA01131679; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ACTA01139679; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ACTA01147678; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 9646.ENSAMEP00000016757; -.
DR Ensembl; ENSAMET00000017447; ENSAMEP00000016757; ENSAMEG00000015869.
DR eggNOG; ENOG502QVMD; Eukaryota.
DR GeneTree; ENSGT00730000111187; -.
DR HOGENOM; CLU_000551_0_0_1; -.
DR InParanoid; G1MBM9; -.
DR OMA; YNAQLVQ; -.
DR TreeFam; TF101133; -.
DR Proteomes; UP000008912; Unassembled WGS sequence.
DR GO; GO:0097539; C:ciliary transition fiber; IEA:Ensembl.
DR GO; GO:0000940; C:condensed chromosome outer kinetochore; IEA:Ensembl.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0030496; C:midbody; IEA:Ensembl.
DR GO; GO:0005635; C:nuclear envelope; IEA:Ensembl.
DR GO; GO:0016363; C:nuclear matrix; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0000922; C:spindle pole; IEA:Ensembl.
DR GO; GO:0070840; F:dynein complex binding; IEA:Ensembl.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0008022; F:protein C-terminus binding; IEA:Ensembl.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR GO; GO:0008134; F:transcription factor binding; IEA:Ensembl.
DR GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR GO; GO:0051310; P:metaphase plate congression; IEA:Ensembl.
DR GO; GO:0000278; P:mitotic cell cycle; IEA:Ensembl.
DR GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR GO; GO:0015031; P:protein transport; IEA:Ensembl.
DR GO; GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:Ensembl.
DR GO; GO:0021591; P:ventricular system development; IEA:Ensembl.
DR InterPro; IPR043513; Cenp-F.
DR InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR InterPro; IPR018463; Centromere_CenpF_N.
DR PANTHER; PTHR18874; PTHR18874; 2.
DR Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR Pfam; PF10473; CENP-F_leu_zip; 3.
DR Pfam; PF10481; CENP-F_N; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000008912}.
FT DOMAIN 1..307
FT /note="CENP-F_N"
FT /evidence="ECO:0000259|Pfam:PF10481"
FT DOMAIN 1893..2033
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2129..2268
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2311..2450
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2967..3010
FT /note="CENP-F_C_Rb_bdg"
FT /evidence="ECO:0000259|Pfam:PF10490"
FT REGION 241..273
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1358..1384
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2902..3111
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 13..138
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 164..191
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 273..342
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 350..377
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 386..438
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 467..487
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 531..616
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 624..644
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 652..672
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 687..714
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 726..760
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 840..867
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 900..948
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 956..997
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1030..1085
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1119..1160
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1203..1244
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1294..1321
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1398..1418
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1551..1614
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1790..1852
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1890..1910
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1932..1959
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1967..1997
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2007..2083
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2105..2125
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2140..2202
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2231..2276
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2294..2314
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2322..2458
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2501..2601
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2616..2675
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2680..2714
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2716..2736
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2751..2823
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2831..2861
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2869..2889
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 246..273
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1364..1380
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2913..2929
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2952..2981
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3001..3056
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3111 AA; 357322 MW; 4375EF26E9121148 CRC64;
MSWALEEWKE GLPTRALQKI QELEGQLDKL KKERQQRQFQ LETLEAALQK QKQKVENEKT
EGTNLKRENQ SLMEICENLE KTKQKISHEL QVKESQVNFQ EGQLNSSKKQ IEKLEQELKR
YKSELERSQQ AAQAADVSLY SSSTPQKIFA TPLTPSQNYS GSKYEDLKEK YNKEVEERKR
LEAEVKALQA KKASQAIPQS TMNHRDIARH QASSSVFSWQ QEKTPTRLSL NALKTPIRRD
FSASHFSGEQ EVTPSGSTSQ TGKRDANSSF CDNSSNSHLL DQLKAQNQEL RNKISDLELH
LQGQEKEMKG QANKCQELQL QLEKAKAELI EKEKALNKSR DELVRSTAQY DQASTKCTAL
EQKLKRLSED LSCQRQNAES ARCSLEQKLK EKEKEFQEEL SRQQRTFQAL DQECAQMKAR
LTQELQQAKN THNILQADLD KVTSGKYQLE KTLEEFKQKF CRTEQALQAS QVKENELRRS
SEEAKKEYSL LKGQSEQRAR EVCHLEEELR KAKQSLSQSQ NVAEEMRVAK NASQETMLRD
LQEKVNQQEN SLTLDKLKLA LVDLEKQRDC SQDLLKKREH HIEQLNDKLS KMEKESESLL
IALELKKKEY EELKEEKTLF ARWKSENEQL LSQLESEKGS LQSKINHLET CLKTQQIKSH
EYNEKVRTLE MESENLHVEI RNLHNMIDSK TVEVETQKQA YADLQQKAEF SDQKHKKETE
NMCLKISELT GQVEDLEHKL QLLSSEVIDK DQRYQDLQAE YESLGDLLKS KDSSLVTNEA
HHRSLLAFEQ QSAMNNSFVN IIGEQGSTPP ERSQCHLEAI PSPKSSAILQ NRVMSLEFSL
ESQKQMNSDL QKQCEELVQI KGEIEENLIK AEQMHQSFVA ETSQRISKLQ EDTSVHQNAF
AETLVALENK EREIQLLNEK LETEQAEIQE LKKSNHLLQE SLKVLQLLSE TLSSEKKEMS
STISLNRKEI EDLTQENETL KEINATLNQE KINLLQKSES FSNCIAERDK SISELSNQYK
QERLILQQRC EETGRAFEDL SEKYQAAQEK NSQLECLLNE CTSACENRQK ELDHLKETFA
REQEAFVTKL ALAEETNQNL VLELGAVQQD LRSEITDIQN NSKSEADGLK REIMTLKEEH
SKMQKELNAL MQENEHLMML METKQEHQIL ESEPINDSVE GESEINKCHV QLPMDLEVKD
PSLDCYNAQL MQLEAKRRNK ELKLQESEKD KERLQHELQT IGIELEAGNL QRDAQSQELS
GPKDCDIGTE EKYISVLHEL SASQNDNALL QCSLQTAMSK LSELEKMCEM LQVEKLELMS
ELNDSRSECI TATSKMAEEM EKLVNEVKIL NDENGLLQGE SVKEMAEGES DERQNEQKHA
SFNSLDDSNC YEHLTLSNKE VQMHFAELQE KFSSLQSEHK VLYDQHRQVS SKLSELQSYV
DTLKAENSIL STSLRNFQGD SVKEEMLGPE EGHFLSLSFS CMTDSPSLTR LGGSSFCKDL
LDQTGETSLL NNLEGTISAN QSNIDEGSCC SPEEEKNLTR KEILSAPARS IEELETLCQM
YLQSLKKLED KIESQEIMKN KEIKELEQLL SSEREELDCL RKQYLSENEQ WQQKLTSVTM
EMESKLAAEK KQTEHLSFEL EVARLQLQGL DLSSRSLLGP DIEDALQVGN NSCDVKESEE
RTLETKERTP KHDIHQICEE GVQQDLNLEM GKVTKTSPVR FTGEWSREQS LETPAEDKTE
GCLERISDLS FSGPNALVPM DFLETQVTIQ NLQLQVKESS NENLRLLHII EERDKKVESL
LNEIKELDSK FHVQKAQITA EMEACIELEK MVEELKKEKS NLSERLEYLS CDKQELHQRT
EGLEGLNSSL EICADKLSHA IIEDSVAKVS DNWRERLLDV ENELKRIQSE KGSIEHHALS
LEADLETVQT EKLYLEKDNE NQQNVIIRLE EELSVVTSER NRLHGELDTL SKENKELDLM
SEKMKQKIRE LESHQGECHI DVAGAEVREQ TQLIETLSSD VTKLLEENTH LQEQLQSLEK
DSQALSLVKS ELEIQIKQLN QEKESLARES ESLQTRLHES EHEKLTVAKA LEGALLEKGE
VAVRLSSTQE EVHQLRQGIE KLRVRIEADD KKQLHVLEKL RESERKADSL QDKVENLERE
LQMSEENQEL VILDAENSKA EVEALKTQME LMTKNLRDLE LDLGTIRFEK ENLVKQLQDK
QGQVSELDTL LSSLKGRLEE EEQGKIEMRE ESKAALEMLQ TQLKELNEEV IALCHDQEIQ
KVEEEILDPS VQEIHQLRNS IEKLKVRLEA DEKEQLQVLG KLTESEHHVD LLKDRVENLE
RELERSRENR ERVILEAENS KAEVGTLKAK IEEMAQTLRD LELDLVHIRS EKENVIKELQ
KEQGRVSELE ILNSSFENLL QEKEQEKVQI REESKIAVET LQTQLKELNE KVVALCQDQD
TWKAQAQSLR TQVDALGYEK AQLLQGLDEV KNNYLNVQSS ANGLLQQVED GKQKLEKKDE
EINILKNQVQ DREQLASKLS QVEGEQQLWK KQKVELENLM VELEEKIQVL QSKNDTLQDT
LEALQDSHRD LEKELELTKM ENVSFVEKVN AMTGKETELQ REMHEMAQKT TELKEEFFGE
KNRLTEELNI MSQEIKSSKD QLKELMLENS ELKKSLDYIH KDQMEKEEKV QEERAEYQLQ
LQEAEKKHQA LLLDTNKQYE MEIQTYREKL SSQEECLSLQ KAEVDLLKSS KEELNNSLKA
TTQILEELKK TKADNVKYTN QLKKENERAQ GKIKLLIKSC KQLEEEKEML QKELSHLEAA
QEKQKTGTVV DSNVEELMAE IKELKETLEE KNKEADEYLD KYCSLLISHE KLEKAKEMLE
TQVARLSSQS KLNLQHSPLL NSVVPEASPA PSATEKKLSS SQSKASGKRQ RSTGIREDGR
GTAPSTPETF SKKSRKAVKS GIHPAEDARD TEFEPEGLPE VVRKGFADIP TGKASPYVLR
RTTMPTRTSP RLAAQKLATS PLSLNKENHA ETSQPTAGGS RSQKVKVAQQ SPADSSAPFR
EPIMRSPSVS NLPERSPANS PREGLRAKRG RLAPSPEAVP ESKSSENCRV Q
//
