ID G1MI02_AILME Unreviewed; 338 AA.
AC G1MI02;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Mono-ADP ribosylhydrolase 1 {ECO:0000313|Ensembl:ENSAMEP00000018987.2};
GN Name=MACROD1 {ECO:0000313|Ensembl:ENSAMEP00000018987.2};
OS Ailuropoda melanoleuca (Giant panda).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda.
OX NCBI_TaxID=9646 {ECO:0000313|Ensembl:ENSAMEP00000018987.2, ECO:0000313|Proteomes:UP000008912};
RN [1] {ECO:0000313|Ensembl:ENSAMEP00000018987.2, ECO:0000313|Proteomes:UP000008912}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20010809; DOI=10.1038/nature08696;
RA Li R., Fan W., Tian G., Zhu H., He L., Cai J., Huang Q., Cai Q., Li B.,
RA Bai Y., Zhang Z., Zhang Y., Wang W., Li J., Wei F., Li H., Jian M., Li J.,
RA Zhang Z., Nielsen R., Li D., Gu W., Yang Z., Xuan Z., Ryder O.A.,
RA Leung F.C., Zhou Y., Cao J., Sun X., Fu Y., Fang X., Guo X., Wang B.,
RA Hou R., Shen F., Mu B., Ni P., Lin R., Qian W., Wang G., Yu C., Nie W.,
RA Wang J., Wu Z., Liang H., Min J., Wu Q., Cheng S., Ruan J., Wang M.,
RA Shi Z., Wen M., Liu B., Ren X., Zheng H., Dong D., Cook K., Shan G.,
RA Zhang H., Kosiol C., Xie X., Lu Z., Zheng H., Li Y., Steiner C.C.,
RA Lam T.T., Lin S., Zhang Q., Li G., Tian J., Gong T., Liu H., Zhang D.,
RA Fang L., Ye C., Zhang J., Hu W., Xu A., Ren Y., Zhang G., Bruford M.W.,
RA Li Q., Ma L., Guo Y., An N., Hu Y., Zheng Y., Shi Y., Li Z., Liu Q.,
RA Chen Y., Zhao J., Qu N., Zhao S., Tian F., Wang X., Wang H., Xu L., Liu X.,
RA Vinar T., Wang Y., Lam T.W., Yiu S.M., Liu S., Zhang H., Li D., Huang Y.,
RA Wang X., Yang G., Jiang Z., Wang J., Qin N., Li L., Li J., Bolund L.,
RA Kristiansen K., Wong G.K., Olson M., Zhang X., Li S., Yang H., Wang J.,
RA Wang J.;
RT "The sequence and de novo assembly of the giant panda genome.";
RL Nature 463:311-317(2010).
RN [2] {ECO:0000313|Ensembl:ENSAMEP00000018987.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G1MI02; -.
DR STRING; 9646.ENSAMEP00000018987; -.
DR Ensembl; ENSAMET00000019748.2; ENSAMEP00000018987.2; ENSAMEG00000017979.2.
DR eggNOG; KOG2633; Eukaryota.
DR GeneTree; ENSGT00940000161450; -.
DR HOGENOM; CLU_046550_3_0_1; -.
DR InParanoid; G1MI02; -.
DR TreeFam; TF341440; -.
DR Proteomes; UP000008912; Unassembled WGS sequence.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0140293; F:ADP-ribosylglutamate hydrolase activity; IEA:Ensembl.
DR GO; GO:0019213; F:deacetylase activity; IEA:Ensembl.
DR GO; GO:0006974; P:DNA damage response; IEA:Ensembl.
DR GO; GO:0042278; P:purine nucleoside metabolic process; IEA:Ensembl.
DR CDD; cd02908; Macro_OAADPr_deacetylase; 1.
DR Gene3D; 3.40.220.10; Leucine Aminopeptidase, subunit E, domain 1; 1.
DR InterPro; IPR002589; Macro_dom.
DR InterPro; IPR043472; Macro_dom-like.
DR PANTHER; PTHR11106:SF120; ADP-RIBOSE GLYCOHYDROLASE MACROD1; 1.
DR PANTHER; PTHR11106; GANGLIOSIDE INDUCED DIFFERENTIATION ASSOCIATED PROTEIN 2-RELATED; 1.
DR Pfam; PF01661; Macro; 1.
DR SMART; SM00506; A1pp; 1.
DR SUPFAM; SSF52949; Macro domain-like; 1.
DR PROSITE; PS51154; MACRO; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008912}.
FT DOMAIN 143..324
FT /note="Macro"
FT /evidence="ECO:0000259|PROSITE:PS51154"
FT REGION 29..73
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 338 AA; 36322 MW; 65A558AB95E63A82 CRC64;
MSLRSQVSGR LAQLRAAGQL LCVPRPWPGP SAGATRTRSS ACGSPGVPGR GQPRLAAPSG
SWGLGGGGGG AERSAGVRTW APLAMAAKVD LSTSTDWKEA KSFLKGLSDK QREEHYFCKD
FIRLKKIPTW KETAKGVTTK VEEPKYKKDK QLNEKVSLFR GDITKLEVDA IVNAANSSLL
GGGGVDGCIH RAAGPLLTDE CRTLQSCETG KAKITGGYRL PAKYVIHTVG PIAHGEPSAS
QAAELRSCYL SSLDLLLEHR LRSAAFPCIS TGVFGYPSEA AAEVVLAALR EWLEQHKDKV
DRLIICVFLE KDESVYLQRL PHYFPADSPG PTGPRSQL
//
