ID G1MQA1_MELGA Unreviewed; 389 AA.
AC G1MQA1;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 3.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=SH2 domain-containing protein {ECO:0000259|PROSITE:PS50001};
OS Meleagris gallopavo (Wild turkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Meleagridinae; Meleagris.
OX NCBI_TaxID=9103 {ECO:0000313|Ensembl:ENSMGAP00000000245.3, ECO:0000313|Proteomes:UP000001645};
RN [1] {ECO:0000313|Ensembl:ENSMGAP00000000245.3, ECO:0000313|Proteomes:UP000001645}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20838655; DOI=10.1371/journal.pbio.1000475;
RA Dalloul R.A., Long J.A., Zimin A.V., Aslam L., Beal K., Blomberg L.A.,
RA Bouffard P., Burt D.W., Crasta O., Crooijmans R.P., Cooper K.,
RA Coulombe R.A., De S., Delany M.E., Dodgson J.B., Dong J.J., Evans C.,
RA Frederickson K.M., Flicek P., Florea L., Folkerts O., Groenen M.A.,
RA Harkins T.T., Herrero J., Hoffmann S., Megens H.J., Jiang A., de Jong P.,
RA Kaiser P., Kim H., Kim K.W., Kim S., Langenberger D., Lee M.K., Lee T.,
RA Mane S., Marcais G., Marz M., McElroy A.P., Modise T., Nefedov M.,
RA Notredame C., Paton I.R., Payne W.S., Pertea G., Prickett D., Puiu D.,
RA Qioa D., Raineri E., Ruffier M., Salzberg S.L., Schatz M.C., Scheuring C.,
RA Schmidt C.J., Schroeder S., Searle S.M., Smith E.J., Smith J.,
RA Sonstegard T.S., Stadler P.F., Tafer H., Tu Z.J., Van Tassell C.P.,
RA Vilella A.J., Williams K.P., Yorke J.A., Zhang L., Zhang H.B., Zhang X.,
RA Zhang Y., Reed K.M.;
RT "Multi-platform next-generation sequencing of the domestic turkey
RT (Meleagris gallopavo): genome assembly and analysis.";
RL PLoS Biol. 8:E1000475-E1000475(2010).
RN [2] {ECO:0000313|Ensembl:ENSMGAP00000000245.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G1MQA1; -.
DR Ensembl; ENSMGAT00000000879.3; ENSMGAP00000000245.3; ENSMGAG00000000858.3.
DR GeneTree; ENSGT00940000159452; -.
DR HOGENOM; CLU_029444_2_0_1; -.
DR InParanoid; G1MQA1; -.
DR TreeFam; TF325799; -.
DR Proteomes; UP000001645; Chromosome 12.
DR Bgee; ENSMGAG00000000858; Expressed in heart and 17 other cell types or tissues.
DR CDD; cd10392; SH2_SHF; 1.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR InterPro; IPR035044; SHF_SH2.
DR PANTHER; PTHR15127; HEAVYWEIGHT, ISOFORM A; 1.
DR PANTHER; PTHR15127:SF28; SH2 DOMAIN-CONTAINING ADAPTER PROTEIN F; 1.
DR Pfam; PF00017; SH2; 1.
DR PRINTS; PR00401; SH2DOMAIN.
DR SMART; SM00252; SH2; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR PROSITE; PS50001; SH2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001645};
KW SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191}.
FT DOMAIN 289..384
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT REGION 157..188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 166..182
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 389 AA; 41910 MW; 1C57BF7901AF6D5F CRC64;
DLRSILRCWN LPAGPPVETL RAASALPSLL LQTACSHLII DCFSYRNLAV TWSFAGSGCL
SGQPAPFPLP PLFLLSPPLA PSLLVVAVGP LGWHRAPGNS VFTLTAAVLL TRSGVADIFF
LSLLFLSFSY SLFLPLPHPS SYPVEIKVIK DLPWPPPVGQ LDSGETPPDS EASASVPPQH
GLQSYEDANG IPCSSAAAPR ALLVRPQAEL IPEREGPNGK LPASLCTTNA GPSEGLGYGR
TSPCREEKAR AALRHGTSSL KGTKALSTEP GPFIGERIDP ALPLESQCWY HGAISRTDAE
TLLRLCKEAS YLVRNSETSK NDFSLSLKSS QGFMHMKLSR TQENKYVLGQ HSPPFDSVPE
IIHHYASRKL PIKGAEHMSL LYPVAIRTL
//
