ID G1MRT7_MELGA Unreviewed; 735 AA.
AC G1MRT7;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 2.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMGAP00000000940.2};
OS Meleagris gallopavo (Wild turkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Meleagridinae; Meleagris.
OX NCBI_TaxID=9103 {ECO:0000313|Ensembl:ENSMGAP00000000940.2, ECO:0000313|Proteomes:UP000001645};
RN [1] {ECO:0000313|Ensembl:ENSMGAP00000000940.2, ECO:0000313|Proteomes:UP000001645}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20838655; DOI=10.1371/journal.pbio.1000475;
RA Dalloul R.A., Long J.A., Zimin A.V., Aslam L., Beal K., Blomberg L.A.,
RA Bouffard P., Burt D.W., Crasta O., Crooijmans R.P., Cooper K.,
RA Coulombe R.A., De S., Delany M.E., Dodgson J.B., Dong J.J., Evans C.,
RA Frederickson K.M., Flicek P., Florea L., Folkerts O., Groenen M.A.,
RA Harkins T.T., Herrero J., Hoffmann S., Megens H.J., Jiang A., de Jong P.,
RA Kaiser P., Kim H., Kim K.W., Kim S., Langenberger D., Lee M.K., Lee T.,
RA Mane S., Marcais G., Marz M., McElroy A.P., Modise T., Nefedov M.,
RA Notredame C., Paton I.R., Payne W.S., Pertea G., Prickett D., Puiu D.,
RA Qioa D., Raineri E., Ruffier M., Salzberg S.L., Schatz M.C., Scheuring C.,
RA Schmidt C.J., Schroeder S., Searle S.M., Smith E.J., Smith J.,
RA Sonstegard T.S., Stadler P.F., Tafer H., Tu Z.J., Van Tassell C.P.,
RA Vilella A.J., Williams K.P., Yorke J.A., Zhang L., Zhang H.B., Zhang X.,
RA Zhang Y., Reed K.M.;
RT "Multi-platform next-generation sequencing of the domestic turkey
RT (Meleagris gallopavo): genome assembly and analysis.";
RL PLoS Biol. 8:E1000475-E1000475(2010).
RN [2] {ECO:0000313|Ensembl:ENSMGAP00000000940.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the GcvT family.
CC {ECO:0000256|ARBA:ARBA00008609}.
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DR AlphaFoldDB; G1MRT7; -.
DR Ensembl; ENSMGAT00000001588.2; ENSMGAP00000000940.2; ENSMGAG00000001456.2.
DR GeneTree; ENSGT00940000159082; -.
DR HOGENOM; CLU_007884_11_0_1; -.
DR TreeFam; TF314735; -.
DR Proteomes; UP000001645; Chromosome 13.
DR Bgee; ENSMGAG00000001456; Expressed in heart and 18 other cell types or tissues.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 2.40.30.110; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.70.1400; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR006076; FAD-dep_OxRdtase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR032503; FAO_M.
DR InterPro; IPR028896; GCST/YgfZ/DmdA.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR43757:SF9; SARCOSINE DEHYDROGENASE; 1.
DR Pfam; PF01266; DAO; 1.
DR Pfam; PF16350; FAO_M; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001645}.
FT DOMAIN 55..258
FT /note="FAD dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF01266"
FT DOMAIN 261..316
FT /note="FAD dependent oxidoreductase central"
FT /evidence="ECO:0000259|Pfam:PF16350"
FT DOMAIN 318..594
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 622..714
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
SQ SEQUENCE 735 AA; 83426 MW; D6CCDBC1318E9F8C CRC64;
QGGCGCPIPG GIQGQAGCGS GQPGLLVGDL HTAGELSDSS LTPGYEGWWW ADLLLSSAGV
QIHERTSVSH VSVQKGRVTG VETDRGHIKC QYFVNCAGQW AYELGHSGEE PVNIPLHACE
HFYLLTHPLK EPLANNVPTV VDPDGRIYIR NWQGGILSGG FEKNPKPLFT EGRNQLEIHN
LQEDWDHFEP LLSSLLRRMP NLEALQIMQL VNCPESFTPD MRCIMGESPT VRGYFVLAGM
NSAGISYGGG AGKYLAEWMV NGYPSENVWP LDLKRFGTLQ SSRTFLRHRV MEVMPLMCDL
KVPRWDFQTG RQLRTSPLYD RLDAQGARWM EKHGFERVKY FVPPGKDLLD LDQSKTFYKP
DWFDIVGSEV KCCKEAVCVI DMSSFTKFEI SSTGDQALQS LQYLFSNDLD VPVGHVVHTG
MLNENGGYEN DCSIARLSKR SFFMISPTDQ QVHCWAWLKN HLPEDSNLTI EDVTWKYTAL
NLIGPRAVDV LSELSYAPMT PEHFPSFFCK EMSVGYANGI RVMSITHTGE PGFMLYIPIE
YALHVYNEVM NMGQKYGIRN AGYYALRSLR IEKFFAFWGQ DLDAFTTPME CGREFQVKLE
KGMEFVGQEA LLEQKQNGVY KRFTMFILED HDTDMDLWPW WGEPIFRNGR YVGKTTSSAY
SYTLERHVCL GFVQHLDEKT GEELVVTTDF INQGEYEIDI AGQRFQAKAK LYPFSSLFAQ
RRRKDEVELS GYQRE
//
