ID G1MT42_MELGA Unreviewed; 828 AA.
AC G1MT42;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 2.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=FCH and double SH3 domains 1 {ECO:0000313|Ensembl:ENSMGAP00000001545.2};
GN Name=FCHSD1 {ECO:0000313|Ensembl:ENSMGAP00000001545.2};
OS Meleagris gallopavo (Wild turkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Meleagridinae; Meleagris.
OX NCBI_TaxID=9103 {ECO:0000313|Ensembl:ENSMGAP00000001545.2, ECO:0000313|Proteomes:UP000001645};
RN [1] {ECO:0000313|Ensembl:ENSMGAP00000001545.2, ECO:0000313|Proteomes:UP000001645}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20838655; DOI=10.1371/journal.pbio.1000475;
RA Dalloul R.A., Long J.A., Zimin A.V., Aslam L., Beal K., Blomberg L.A.,
RA Bouffard P., Burt D.W., Crasta O., Crooijmans R.P., Cooper K.,
RA Coulombe R.A., De S., Delany M.E., Dodgson J.B., Dong J.J., Evans C.,
RA Frederickson K.M., Flicek P., Florea L., Folkerts O., Groenen M.A.,
RA Harkins T.T., Herrero J., Hoffmann S., Megens H.J., Jiang A., de Jong P.,
RA Kaiser P., Kim H., Kim K.W., Kim S., Langenberger D., Lee M.K., Lee T.,
RA Mane S., Marcais G., Marz M., McElroy A.P., Modise T., Nefedov M.,
RA Notredame C., Paton I.R., Payne W.S., Pertea G., Prickett D., Puiu D.,
RA Qioa D., Raineri E., Ruffier M., Salzberg S.L., Schatz M.C., Scheuring C.,
RA Schmidt C.J., Schroeder S., Searle S.M., Smith E.J., Smith J.,
RA Sonstegard T.S., Stadler P.F., Tafer H., Tu Z.J., Van Tassell C.P.,
RA Vilella A.J., Williams K.P., Yorke J.A., Zhang L., Zhang H.B., Zhang X.,
RA Zhang Y., Reed K.M.;
RT "Multi-platform next-generation sequencing of the domestic turkey
RT (Meleagris gallopavo): genome assembly and analysis.";
RL PLoS Biol. 8:E1000475-E1000475(2010).
RN [2] {ECO:0000313|Ensembl:ENSMGAP00000001545.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G1MT42; -.
DR Ensembl; ENSMGAT00000002208.2; ENSMGAP00000001545.2; ENSMGAG00000002002.2.
DR GeneTree; ENSGT00510000046732; -.
DR HOGENOM; CLU_013546_0_0_1; -.
DR InParanoid; G1MT42; -.
DR TreeFam; TF324557; -.
DR Proteomes; UP000001645; Chromosome 15.
DR Bgee; ENSMGAG00000002002; Expressed in spleen and 15 other cell types or tissues.
DR GO; GO:0032437; C:cuticular plate; IEA:Ensembl.
DR GO; GO:0061024; P:membrane organization; IEA:Ensembl.
DR GO; GO:0030838; P:positive regulation of actin filament polymerization; IEA:Ensembl.
DR CDD; cd07678; F-BAR_FCHSD1; 1.
DR CDD; cd11895; SH3_FCHSD1_2; 1.
DR CDD; cd11761; SH3_FCHSD_1; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 2.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR001060; FCH_dom.
DR InterPro; IPR035460; FCHSD_SH3_1.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR15735:SF4; F-BAR AND DOUBLE SH3 DOMAINS PROTEIN 1; 1.
DR PANTHER; PTHR15735; FCH AND DOUBLE SH3 DOMAINS PROTEIN; 1.
DR Pfam; PF00611; FCH; 1.
DR Pfam; PF00018; SH3_1; 1.
DR Pfam; PF14604; SH3_9; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00055; FCH; 1.
DR SMART; SM00326; SH3; 2.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 2.
DR PROSITE; PS51741; F_BAR; 1.
DR PROSITE; PS50002; SH3; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077, ECO:0000256|SAM:Coils};
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Reference proteome {ECO:0000313|Proteomes:UP000001645};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 146..420
FT /note="F-BAR"
FT /evidence="ECO:0000259|PROSITE:PS51741"
FT DOMAIN 588..649
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 686..749
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 7..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 751..828
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 254..302
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 18..32
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 828 AA; 91076 MW; 542A177B47DE3D36 CRC64;
MSFILMFPGS LHPRVPSQRR MQRTEHQEGR GGEGAWRGGG GAGPACAEWA WPLGGVVYGK
RAWSTRGGVW SSVNGRGLYW WAGVCSKWAW PTENGPGSAV GVVCSGGRGL ERRGGAEPQF
RATHTRCAAG CGVGEMQPPP RKGKLSQVVK LHFAEQLCGL QSKQQRDAEL LEDIRSYSKQ
RAAIEREYGQ ALQRLASQFV KRDWQRGRSD AGDSRSVFAV WKGIIEGTAY TGQARVTASE
SYRSLAAEAT KSSRMSKERM LKKSMEQLQK AQAELLETVK ELDKAKKQFS HLQRSSEVAK
DKAADVEARL RKSDRRIFHT KASLQKLSAK FSMQMAEYSK QRAGVQNEYV LTLVSANAHL
EHYYHVELPA IMQALDGDLY ERLRDHLSTA GRAEVESCEI TQDWFQRISE AAARVCREQD
LLLFLQDHTA FMLVPEQRFQ LDGIQEMSLL QPEDGGASLE KEARRWAMRA TRDSKNKAHG
EEVLQRLEAR RHQVPEAEVA AVERQMEEVR ENIWKAEVGR AKAEARLALL RTAGLDVDSW
LAGAVRAGVE LPRTPSTEAP TGLDPTEFDD YDSDETFEEA EPGHAARTYP YTCRVIFGYQ
GCHADELSIA QGEELEVIED GDMEEWVKAR NKAGQVGYVP EKYLLCLSCV GSESGSAAST
GTTGPSGAAL QRQLSSIMAA ELVLEPGAWL VRALYDYEGQ SPEELSFPEG AIIRVLPRAE
DEVDDGFWTG DFDGRVGVFP SLVVEELTGA RGTAGQELPS PSPPPFSPPG LALSASLGSG
PELLLEVCRH EGTSSGQSSP DLAANRIRPL RAPPPPPGRA PDLEQDLS
//
