ID G1MUH8_MELGA Unreviewed; 986 AA.
AC G1MUH8;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 3.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=NLR family member X1 {ECO:0000313|Ensembl:ENSMGAP00000002189.3};
GN Name=NLRX1 {ECO:0000313|Ensembl:ENSMGAP00000002189.3};
OS Meleagris gallopavo (Wild turkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Meleagridinae; Meleagris.
OX NCBI_TaxID=9103 {ECO:0000313|Ensembl:ENSMGAP00000002189.3, ECO:0000313|Proteomes:UP000001645};
RN [1] {ECO:0000313|Ensembl:ENSMGAP00000002189.3, ECO:0000313|Proteomes:UP000001645}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20838655; DOI=10.1371/journal.pbio.1000475;
RA Dalloul R.A., Long J.A., Zimin A.V., Aslam L., Beal K., Blomberg L.A.,
RA Bouffard P., Burt D.W., Crasta O., Crooijmans R.P., Cooper K.,
RA Coulombe R.A., De S., Delany M.E., Dodgson J.B., Dong J.J., Evans C.,
RA Frederickson K.M., Flicek P., Florea L., Folkerts O., Groenen M.A.,
RA Harkins T.T., Herrero J., Hoffmann S., Megens H.J., Jiang A., de Jong P.,
RA Kaiser P., Kim H., Kim K.W., Kim S., Langenberger D., Lee M.K., Lee T.,
RA Mane S., Marcais G., Marz M., McElroy A.P., Modise T., Nefedov M.,
RA Notredame C., Paton I.R., Payne W.S., Pertea G., Prickett D., Puiu D.,
RA Qioa D., Raineri E., Ruffier M., Salzberg S.L., Schatz M.C., Scheuring C.,
RA Schmidt C.J., Schroeder S., Searle S.M., Smith E.J., Smith J.,
RA Sonstegard T.S., Stadler P.F., Tafer H., Tu Z.J., Van Tassell C.P.,
RA Vilella A.J., Williams K.P., Yorke J.A., Zhang L., Zhang H.B., Zhang X.,
RA Zhang Y., Reed K.M.;
RT "Multi-platform next-generation sequencing of the domestic turkey
RT (Meleagris gallopavo): genome assembly and analysis.";
RL PLoS Biol. 8:E1000475-E1000475(2010).
RN [2] {ECO:0000313|Ensembl:ENSMGAP00000002189.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G1MUH8; -.
DR Ensembl; ENSMGAT00000002863.3; ENSMGAP00000002189.3; ENSMGAG00000002589.3.
DR GeneTree; ENSGT00940000159493; -.
DR HOGENOM; CLU_016769_0_0_1; -.
DR TreeFam; TF331068; -.
DR Proteomes; UP000001645; Chromosome 26.
DR Bgee; ENSMGAG00000002589; Expressed in thymus and 16 other cell types or tissues.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR007111; NACHT_NTPase.
DR InterPro; IPR048900; NLRX1_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR24106; NACHT, LRR AND CARD DOMAINS-CONTAINING; 1.
DR PANTHER; PTHR24106:SF152; NLR FAMILY MEMBER X1; 1.
DR Pfam; PF13516; LRR_6; 1.
DR Pfam; PF05729; NACHT; 1.
DR Pfam; PF21402; NLRX1_C; 1.
DR SMART; SM00368; LRR_RI; 4.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS50837; NACHT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001645};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..986
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5032300352"
FT DOMAIN 174..307
FT /note="NACHT"
FT /evidence="ECO:0000259|PROSITE:PS50837"
SQ SEQUENCE 986 AA; 111008 MW; C5ADF471BD4DBF90 CRC64;
MSRAMQYHGW LPWGSWTLLC GSQPGCRAAR CVYLCAASGP GSCFHRKILH VGGISLPRSC
VRYKGGSQEN RAQRSSSHHG LDHLRNVASS DAIKKHQKSL SAWFSNQPNE ERQFGPSFSL
DAVHVDPVIR ESSLEQILKP SPDLTIQHQL QQPCRQVISL QNLFDVDACG RQVKNVVLYG
TVGTGKSTLI KKMVVDWCHG LLPRFELVIP FSCEDLSYSH VPISLRRLIT KKYQHLRDVV
PLLGSSNLKV LFILNGLERL NLDFRLAGTE LCCDANEPVP PSAIVVNLLR KYLLPEASII
VTTRPSAVHR IPGKYVGRYA EICGFSDTNL QKLYFQLRLS QPGCDGENNV ASRSGEQDNL
VEMLSRNLER QNQIAAACFL PSYCWLVCTT LHFLYFTRTV PPSQTLSGIY TSFLRLNFSG
EVLDSTDPTK ISMMKYVAKT VGKLAHEGVM SRKTSFTEED LQQCFEVEMK TESELNQLEV
FRSDVFRFFL TPCVQPGKEH TFVFTIPAMQ EYLAALYVVL GEKKTLVQKV GKEVSEIIGK
VSEDAAVVLS IISKVLPLRF LPVLFNLLKM FPRFFSRLSG KGRDTIARTM AEELFKEEDY
YNDDVLDQIN SSILGVEGPM RHPDEAADDE VFELFPIFMG GILSRRNRAI LEQLGCSIKN
LAAFEIAKAM KKTVIRNSRK GLPPSELMDY LFFLHEFQNE RFTAEAIRSL RTVNLSSVKM
TPLKCSVLAS VMGSKSHEVE ELNLTSCNLD TGSLRTLFPV LLRCKFLHLQ LNSLGPDACK
EIRDLLLHDK CAVSNLRLGN NPIGEQGAQY LAEALAGNRS LTHLSLLHTA LGDRGVELIA
QHLAENQQLQ ELNLGYNSLT DRAALHVVEV AKKHATLDKV HLYFNDISED GKRALDSLRM
DRDGVRALVF LTAGTDVSDY WSSILNVVHK NLPFWDRERV RQHLTIILQD LESSRRQTVN
PWRKAKFLRV ESEVKKMLGK LQHGTL
//
