ID G1MW20_MELGA Unreviewed; 356 AA.
AC G1MW20;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 2.
DT 27-MAR-2024, entry version 74.
DE RecName: Full=45 kDa calcium-binding protein {ECO:0000256|ARBA:ARBA00023817};
DE AltName: Full=Stromal cell-derived factor 4 {ECO:0000256|ARBA:ARBA00031511};
GN Name=SDF4 {ECO:0000313|Ensembl:ENSMGAP00000002904.2};
OS Meleagris gallopavo (Wild turkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Meleagridinae; Meleagris.
OX NCBI_TaxID=9103 {ECO:0000313|Ensembl:ENSMGAP00000002904.2, ECO:0000313|Proteomes:UP000001645};
RN [1] {ECO:0000313|Ensembl:ENSMGAP00000002904.2, ECO:0000313|Proteomes:UP000001645}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20838655; DOI=10.1371/journal.pbio.1000475;
RA Dalloul R.A., Long J.A., Zimin A.V., Aslam L., Beal K., Blomberg L.A.,
RA Bouffard P., Burt D.W., Crasta O., Crooijmans R.P., Cooper K.,
RA Coulombe R.A., De S., Delany M.E., Dodgson J.B., Dong J.J., Evans C.,
RA Frederickson K.M., Flicek P., Florea L., Folkerts O., Groenen M.A.,
RA Harkins T.T., Herrero J., Hoffmann S., Megens H.J., Jiang A., de Jong P.,
RA Kaiser P., Kim H., Kim K.W., Kim S., Langenberger D., Lee M.K., Lee T.,
RA Mane S., Marcais G., Marz M., McElroy A.P., Modise T., Nefedov M.,
RA Notredame C., Paton I.R., Payne W.S., Pertea G., Prickett D., Puiu D.,
RA Qioa D., Raineri E., Ruffier M., Salzberg S.L., Schatz M.C., Scheuring C.,
RA Schmidt C.J., Schroeder S., Searle S.M., Smith E.J., Smith J.,
RA Sonstegard T.S., Stadler P.F., Tafer H., Tu Z.J., Van Tassell C.P.,
RA Vilella A.J., Williams K.P., Yorke J.A., Zhang L., Zhang H.B., Zhang X.,
RA Zhang Y., Reed K.M.;
RT "Multi-platform next-generation sequencing of the domestic turkey
RT (Meleagris gallopavo): genome assembly and analysis.";
RL PLoS Biol. 8:E1000475-E1000475(2010).
RN [2] {ECO:0000313|Ensembl:ENSMGAP00000002904.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus lumen
CC {ECO:0000256|ARBA:ARBA00023769}.
CC -!- SIMILARITY: Belongs to the CREC family.
CC {ECO:0000256|ARBA:ARBA00006431}.
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DR RefSeq; XP_010721083.1; XM_010722781.2.
DR AlphaFoldDB; G1MW20; -.
DR Ensembl; ENSMGAT00000003594.2; ENSMGAP00000002904.2; ENSMGAG00000003216.2.
DR GeneID; 100541787; -.
DR KEGG; mgp:100541787; -.
DR CTD; 51150; -.
DR GeneTree; ENSGT01010000222360; -.
DR HOGENOM; CLU_044718_1_0_1; -.
DR InParanoid; G1MW20; -.
DR TreeFam; TF314849; -.
DR Proteomes; UP000001645; Chromosome 23.
DR Bgee; ENSMGAG00000003216; Expressed in testis and 17 other cell types or tissues.
DR GO; GO:0005796; C:Golgi lumen; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd16225; EFh_CREC_cab45; 1.
DR Gene3D; 1.10.238.10; EF-hand; 3.
DR InterPro; IPR027240; CAB45_EFh.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR PANTHER; PTHR10827:SF98; 45 KDA CALCIUM-BINDING PROTEIN; 1.
DR PANTHER; PTHR10827; RETICULOCALBIN; 1.
DR Pfam; PF13202; EF-hand_5; 1.
DR Pfam; PF13499; EF-hand_7; 1.
DR SMART; SM00054; EFh; 5.
DR SUPFAM; SSF47473; EF-hand; 2.
DR PROSITE; PS00018; EF_HAND_1; 5.
DR PROSITE; PS50222; EF_HAND_2; 4.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001645};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 30..356
FT /note="45 kDa calcium-binding protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5033026475"
FT DOMAIN 92..127
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 131..166
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 227..262
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 272..307
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
SQ SEQUENCE 356 AA; 41893 MW; D2DABDE2E617F23C CRC64;
MMSRQAFLCS LGSLYLSLLF VFLLMDVYAR PANNSALKEK PADSKDENEI LPPDHLNGVK
MEMDGHLNKE FHQEVFLGKE MEEFEEDSEP RKNRKKLMVI FSKVDIDNDK KISAKEMQRW
IMEKTDEHFQ EAVEENKMHF RAVDPDGDGH VSWDEYKIKF LASKGLNEKE IAEKIKNNEE
LKIDEETQEV LDNLKDRWYQ ADNPPPDMLL NEEEFLSFLH PEHSRGMLKF MVKEIIRDLD
QDGDKKLTLS EFISLPVGTV ENQQAQDIDD DWVKDRRKEF EEVIDANHDG IVTMEELEEY
MDPMNEYNAL NEAKQMIAVA DENQNHHLEL EEILKYSEYF TGSKLMDYAR NVHEEF
//
