ID G1N0J3_MELGA Unreviewed; 540 AA.
AC G1N0J3;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 3.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=Inositol polyphosphate-related phosphatase domain-containing protein {ECO:0000259|SMART:SM00128};
GN Name=INPP5K {ECO:0000313|Ensembl:ENSMGAP00000004943.3};
OS Meleagris gallopavo (Wild turkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Meleagridinae; Meleagris.
OX NCBI_TaxID=9103 {ECO:0000313|Ensembl:ENSMGAP00000004943.3, ECO:0000313|Proteomes:UP000001645};
RN [1] {ECO:0000313|Ensembl:ENSMGAP00000004943.3, ECO:0000313|Proteomes:UP000001645}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20838655; DOI=10.1371/journal.pbio.1000475;
RA Dalloul R.A., Long J.A., Zimin A.V., Aslam L., Beal K., Blomberg L.A.,
RA Bouffard P., Burt D.W., Crasta O., Crooijmans R.P., Cooper K.,
RA Coulombe R.A., De S., Delany M.E., Dodgson J.B., Dong J.J., Evans C.,
RA Frederickson K.M., Flicek P., Florea L., Folkerts O., Groenen M.A.,
RA Harkins T.T., Herrero J., Hoffmann S., Megens H.J., Jiang A., de Jong P.,
RA Kaiser P., Kim H., Kim K.W., Kim S., Langenberger D., Lee M.K., Lee T.,
RA Mane S., Marcais G., Marz M., McElroy A.P., Modise T., Nefedov M.,
RA Notredame C., Paton I.R., Payne W.S., Pertea G., Prickett D., Puiu D.,
RA Qioa D., Raineri E., Ruffier M., Salzberg S.L., Schatz M.C., Scheuring C.,
RA Schmidt C.J., Schroeder S., Searle S.M., Smith E.J., Smith J.,
RA Sonstegard T.S., Stadler P.F., Tafer H., Tu Z.J., Van Tassell C.P.,
RA Vilella A.J., Williams K.P., Yorke J.A., Zhang L., Zhang H.B., Zhang X.,
RA Zhang Y., Reed K.M.;
RT "Multi-platform next-generation sequencing of the domestic turkey
RT (Meleagris gallopavo): genome assembly and analysis.";
RL PLoS Biol. 8:E1000475-E1000475(2010).
RN [2] {ECO:0000313|Ensembl:ENSMGAP00000004943.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase
CC type II family. {ECO:0000256|ARBA:ARBA00005910}.
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DR RefSeq; XP_010720030.2; XM_010721728.2.
DR AlphaFoldDB; G1N0J3; -.
DR Ensembl; ENSMGAT00000005668.3; ENSMGAP00000004943.3; ENSMGAG00000005047.3.
DR GeneID; 100538550; -.
DR KEGG; mgp:100538550; -.
DR CTD; 51763; -.
DR GeneTree; ENSGT00940000156538; -.
DR HOGENOM; CLU_011711_3_2_1; -.
DR TreeFam; TF317034; -.
DR Proteomes; UP000001645; Chromosome 21.
DR Bgee; ENSMGAG00000005047; Expressed in ovary and 17 other cell types or tissues.
DR GO; GO:0052659; F:inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0046856; P:phosphatidylinositol dephosphorylation; IEA:InterPro.
DR CDD; cd09094; INPP5c_INPP5J-like; 1.
DR Gene3D; 2.60.40.2840; -; 1.
DR Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR InterPro; IPR046985; IP5.
DR InterPro; IPR000300; IPPc.
DR InterPro; IPR041611; SKICH.
DR PANTHER; PTHR11200; INOSITOL 5-PHOSPHATASE; 1.
DR PANTHER; PTHR11200:SF117; INOSITOL POLYPHOSPHATE 5-PHOSPHATASE K; 1.
DR Pfam; PF17751; SKICH; 1.
DR SMART; SM00128; IPPc; 1.
DR SUPFAM; SSF56219; DNase I-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001645}.
FT DOMAIN 89..404
FT /note="Inositol polyphosphate-related phosphatase"
FT /evidence="ECO:0000259|SMART:SM00128"
SQ SEQUENCE 540 AA; 62089 MW; 3D29FCFE10A4783D CRC64;
MASLGSEDAF QESAALSLHD LESLHTFRSR SASVSSAGSS GRLQLRQRVA QLMACVEDIS
SDDEVHEEVC RTLDEAFLIW GKKMKDKWRE FRLHLVTWNV GTASPPPDVT SLLQLDSLSP
AMDMYVIGLQ EVNSRITNFL SDLAFDDPWS IFFMSVLSPL GYIKLSSVRM QGLLLLIFVK
HAHLPFIRDV HTHYTRTGLY GYWGNKGGVT IRMSLYGHTI CFINCHLPAH MENTEQRLDD
FEKILEMQFE EENIPNTLDH DVLFWFGDLN FRIADYGIHF VRESINNKRY NLLWEKDQLN
MAKKKEAFLQ EFIEGPLQFK PTYKFDLHSD VYDTSEKKRK PAWTDRILWR VKSLCQRALK
EDDFSEEEQT ISVTLNNYIS HMSYGISDHK PVTGTFELEL KPLLSDPLVT LSPEGEWSAE
HDVLISYSAV PGFPSSAWDW IGLFKVTFRH ANDYVTYAWV EDDEISSNED SKQVYMSAAE
IPDMGGEFLL CYYSNNLQSI VGISQPFQIR PNRTLIGKGP AQEENAWLQK PDNLESHNEF
//
