ID G1N329_MELGA Unreviewed; 663 AA.
AC G1N329;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE RecName: Full=G protein signaling modulator 2 {ECO:0008006|Google:ProtNLM};
GN Name=GPSM2 {ECO:0000313|Ensembl:ENSMGAP00000006088.1};
OS Meleagris gallopavo (Wild turkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Meleagridinae; Meleagris.
OX NCBI_TaxID=9103 {ECO:0000313|Ensembl:ENSMGAP00000006088.1, ECO:0000313|Proteomes:UP000001645};
RN [1] {ECO:0000313|Ensembl:ENSMGAP00000006088.1, ECO:0000313|Proteomes:UP000001645}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20838655; DOI=10.1371/journal.pbio.1000475;
RA Dalloul R.A., Long J.A., Zimin A.V., Aslam L., Beal K., Blomberg L.A.,
RA Bouffard P., Burt D.W., Crasta O., Crooijmans R.P., Cooper K.,
RA Coulombe R.A., De S., Delany M.E., Dodgson J.B., Dong J.J., Evans C.,
RA Frederickson K.M., Flicek P., Florea L., Folkerts O., Groenen M.A.,
RA Harkins T.T., Herrero J., Hoffmann S., Megens H.J., Jiang A., de Jong P.,
RA Kaiser P., Kim H., Kim K.W., Kim S., Langenberger D., Lee M.K., Lee T.,
RA Mane S., Marcais G., Marz M., McElroy A.P., Modise T., Nefedov M.,
RA Notredame C., Paton I.R., Payne W.S., Pertea G., Prickett D., Puiu D.,
RA Qioa D., Raineri E., Ruffier M., Salzberg S.L., Schatz M.C., Scheuring C.,
RA Schmidt C.J., Schroeder S., Searle S.M., Smith E.J., Smith J.,
RA Sonstegard T.S., Stadler P.F., Tafer H., Tu Z.J., Van Tassell C.P.,
RA Vilella A.J., Williams K.P., Yorke J.A., Zhang L., Zhang H.B., Zhang X.,
RA Zhang Y., Reed K.M.;
RT "Multi-platform next-generation sequencing of the domestic turkey
RT (Meleagris gallopavo): genome assembly and analysis.";
RL PLoS Biol. 8:E1000475-E1000475(2010).
RN [2] {ECO:0000313|Ensembl:ENSMGAP00000006088.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the GPSM family.
CC {ECO:0000256|ARBA:ARBA00006600}.
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DR RefSeq; XP_003208689.1; XM_003208641.3.
DR AlphaFoldDB; G1N329; -.
DR Ensembl; ENSMGAT00000006835.2; ENSMGAP00000006088.1; ENSMGAG00000006084.2.
DR GeneID; 100547374; -.
DR KEGG; mgp:100547374; -.
DR CTD; 29899; -.
DR GeneTree; ENSGT00940000154667; -.
DR HOGENOM; CLU_012445_1_0_1; -.
DR OMA; PEDRSFH; -.
DR OrthoDB; 4190321at2759; -.
DR TreeFam; TF328344; -.
DR Proteomes; UP000001645; Chromosome 10.
DR Bgee; ENSMGAG00000006084; Expressed in bursa of Fabricius and 17 other cell types or tissues.
DR GO; GO:0030695; F:GTPase regulator activity; IEA:InterPro.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR InterPro; IPR003109; GoLoco_motif.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR45954:SF3; G-PROTEIN-SIGNALING MODULATOR 2; 1.
DR PANTHER; PTHR45954; LD33695P; 1.
DR Pfam; PF02188; GoLoco; 4.
DR Pfam; PF13374; TPR_10; 1.
DR Pfam; PF13424; TPR_12; 2.
DR Pfam; PF13176; TPR_7; 2.
DR SMART; SM00390; GoLoco; 4.
DR SMART; SM00028; TPR; 7.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50877; GOLOCO; 4.
DR PROSITE; PS50005; TPR; 1.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000001645};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT REPEAT 244..277
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ SEQUENCE 663 AA; 74150 MW; 8E0777C9F81E4D9F CRC64;
MEESNVLISM REDQSFHVRY RMEASCLELA LEGERLCKAG DCRAGVSFFE AAVQVGTEDL
KTLSAIYSQL GNAYFYLHEY AKALEYHHHD LTLARTIGDL VGEAKASGNL GNTLKVLGNF
EEAIVCCQRH LDISRELNDK VGEARALYNL GNVYHSKGKN VACAGTHDPG ELPEDVKNAL
QKAANYYEEN LTIVTELGDR AAQGRAFGNL GNTHYLLGNF RSAVLAHEQR LLIAKEFGDR
SAERRAYSNL GNAYIFLGEF ETASEYYKRT LQLARQLKDR AVEAQACYSL GNTYTLLQDY
EKAIDYHLKH LVIAQELNDK IGEGRACWSL GNAYTALGNH DQAMHFAERH LEISREVGDR
SGELTARLNL SDLQMVLGLS YSTNTSMMSE SHAVDNSLNG TRPRVGRRHS MENMELMKLT
PEKVQNWNSE ILAKQKPLIA KPSAKLHFVN RLKGKKYKNS TASKVLQDAS NSIDHRLPNS
QRRNSRETVA DEGFFDLLSR FQSNRMDDQR CHFQEKNRFS AASVATSSTP TTTIQKSFSA
SVVSPHTDDF LDLLASSQSR RLDDQRASFS NLPGLRLNHR TSPSVLGHLM ASNNRELDED
FFDILIKCQS SRLDDQRCAP PSSAKGPTVP DEDFFSLIVR SQAKRMDEQR VPLPSAIKGS
SAS
//
