ID G1N4U1_MELGA Unreviewed; 557 AA.
AC G1N4U1;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 2.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Gigaxonin {ECO:0000313|Ensembl:ENSMGAP00000006892.2};
GN Name=GAN {ECO:0000313|Ensembl:ENSMGAP00000006892.2};
OS Meleagris gallopavo (Wild turkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Meleagridinae; Meleagris.
OX NCBI_TaxID=9103 {ECO:0000313|Ensembl:ENSMGAP00000006892.2, ECO:0000313|Proteomes:UP000001645};
RN [1] {ECO:0000313|Ensembl:ENSMGAP00000006892.2, ECO:0000313|Proteomes:UP000001645}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20838655; DOI=10.1371/journal.pbio.1000475;
RA Dalloul R.A., Long J.A., Zimin A.V., Aslam L., Beal K., Blomberg L.A.,
RA Bouffard P., Burt D.W., Crasta O., Crooijmans R.P., Cooper K.,
RA Coulombe R.A., De S., Delany M.E., Dodgson J.B., Dong J.J., Evans C.,
RA Frederickson K.M., Flicek P., Florea L., Folkerts O., Groenen M.A.,
RA Harkins T.T., Herrero J., Hoffmann S., Megens H.J., Jiang A., de Jong P.,
RA Kaiser P., Kim H., Kim K.W., Kim S., Langenberger D., Lee M.K., Lee T.,
RA Mane S., Marcais G., Marz M., McElroy A.P., Modise T., Nefedov M.,
RA Notredame C., Paton I.R., Payne W.S., Pertea G., Prickett D., Puiu D.,
RA Qioa D., Raineri E., Ruffier M., Salzberg S.L., Schatz M.C., Scheuring C.,
RA Schmidt C.J., Schroeder S., Searle S.M., Smith E.J., Smith J.,
RA Sonstegard T.S., Stadler P.F., Tafer H., Tu Z.J., Van Tassell C.P.,
RA Vilella A.J., Williams K.P., Yorke J.A., Zhang L., Zhang H.B., Zhang X.,
RA Zhang Y., Reed K.M.;
RT "Multi-platform next-generation sequencing of the domestic turkey
RT (Meleagris gallopavo): genome assembly and analysis.";
RL PLoS Biol. 8:E1000475-E1000475(2010).
RN [2] {ECO:0000313|Ensembl:ENSMGAP00000006892.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G1N4U1; -.
DR Ensembl; ENSMGAT00000007655.2; ENSMGAP00000006892.2; ENSMGAG00000006826.2.
DR GeneTree; ENSGT00940000155273; -.
DR HOGENOM; CLU_004253_14_2_1; -.
DR InParanoid; G1N4U1; -.
DR TreeFam; TF328485; -.
DR Proteomes; UP000001645; Chromosome 13.
DR Bgee; ENSMGAG00000006826; Expressed in liver and 13 other cell types or tissues.
DR GO; GO:0031463; C:Cul3-RING ubiquitin ligase complex; IEA:Ensembl.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0007010; P:cytoskeleton organization; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:Ensembl.
DR CDD; cd18455; BACK_KLHL16_gigaxonin; 1.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR017096; BTB-kelch_protein.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR030579; KLHL16_BACK.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR24412:SF232; GIGAXONIN; 1.
DR PANTHER; PTHR24412; KELCH PROTEIN; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 3.
DR PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00612; Kelch; 5.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000001645};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 94..196
FT /note="BACK"
FT /evidence="ECO:0000259|SMART:SM00875"
SQ SEQUENCE 557 AA; 63384 MW; A04FA6693463C275 CRC64;
TREHADSLFL PIFRLYCKLN YNPPKDDGST YKIELEGISV DIMKEILDYI FSGQIRLNEE
TIQDVVQAAD LLLLTDLKTL CCEFLEGCIA AENCIGIRDF ALHYCLHHVH YLASEYLETH
FRDVSSTEEF LELTPQKLKE VLSMEKLNVG NERYVFEAVI RWISHDSESR KVHMKDVMSA
VWVSGLDAAY LREQMMSEPL VREIVKECNN IPLTPPQQGE AMLASFKPRG YSECIVTVGG
EERVSRKPTS VMRCMCPLYD PNRQLWIELA PMSIPRINHG VLSAEGFLFV LGGQDENKGT
LSSGEKYDPD TNSWSSLPPM NEARHNFGVV EIDGILYILG GEDGERELIS MESYDIYNRT
WTKQPDLTMV RKIGCYAAMK KKIYAMGGGS YGKLFESVEC YDPRTQQWTA ICPLKERRFG
AVACGVASEL YVFGGVRSRD DSQASEMVTC KSEFYHDEFK RWIYLNDQNL CIPTSSSFVY
GAVPIGASIY VIGDLDTGTN YDYVREFKRS TGTWQRTKPL FPSDLRRTGC AALRIANCKL
FRLQLQQGLF RIRVPSP
//
