ID G1NG15_MELGA Unreviewed; 1828 AA.
AC G1NG15;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 3.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMGAP00000011992.3};
OS Meleagris gallopavo (Wild turkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Meleagridinae; Meleagris.
OX NCBI_TaxID=9103 {ECO:0000313|Ensembl:ENSMGAP00000011992.3, ECO:0000313|Proteomes:UP000001645};
RN [1] {ECO:0000313|Ensembl:ENSMGAP00000011992.3, ECO:0000313|Proteomes:UP000001645}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20838655; DOI=10.1371/journal.pbio.1000475;
RA Dalloul R.A., Long J.A., Zimin A.V., Aslam L., Beal K., Blomberg L.A.,
RA Bouffard P., Burt D.W., Crasta O., Crooijmans R.P., Cooper K.,
RA Coulombe R.A., De S., Delany M.E., Dodgson J.B., Dong J.J., Evans C.,
RA Frederickson K.M., Flicek P., Florea L., Folkerts O., Groenen M.A.,
RA Harkins T.T., Herrero J., Hoffmann S., Megens H.J., Jiang A., de Jong P.,
RA Kaiser P., Kim H., Kim K.W., Kim S., Langenberger D., Lee M.K., Lee T.,
RA Mane S., Marcais G., Marz M., McElroy A.P., Modise T., Nefedov M.,
RA Notredame C., Paton I.R., Payne W.S., Pertea G., Prickett D., Puiu D.,
RA Qioa D., Raineri E., Ruffier M., Salzberg S.L., Schatz M.C., Scheuring C.,
RA Schmidt C.J., Schroeder S., Searle S.M., Smith E.J., Smith J.,
RA Sonstegard T.S., Stadler P.F., Tafer H., Tu Z.J., Van Tassell C.P.,
RA Vilella A.J., Williams K.P., Yorke J.A., Zhang L., Zhang H.B., Zhang X.,
RA Zhang Y., Reed K.M.;
RT "Multi-platform next-generation sequencing of the domestic turkey
RT (Meleagris gallopavo): genome assembly and analysis.";
RL PLoS Biol. 8:E1000475-E1000475(2010).
RN [2] {ECO:0000313|Ensembl:ENSMGAP00000011992.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR MEROPS; C19.047; -.
DR Ensembl; ENSMGAT00000012877.3; ENSMGAP00000011992.3; ENSMGAG00000011440.3.
DR GeneTree; ENSGT00940000166247; -.
DR HOGENOM; CLU_000331_1_0_1; -.
DR InParanoid; G1NG15; -.
DR TreeFam; TF323966; -.
DR Proteomes; UP000001645; Chromosome 10.
DR Bgee; ENSMGAG00000011440; Expressed in pectoralis major and 18 other cell types or tissues.
DR GO; GO:0004843; F:cysteine-type deubiquitinase activity; IEA:UniProtKB-EC.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd17065; Ubl_UBP24; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR001394; Peptidase_C19_UCH.
DR InterPro; IPR000626; Ubiquitin-like_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR InterPro; IPR047061; UBP24_Ubl.
DR InterPro; IPR018200; USP_CS.
DR InterPro; IPR028889; USP_dom.
DR PANTHER; PTHR24006; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE; 1.
DR PANTHER; PTHR24006:SF729; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 24; 1.
DR Pfam; PF00443; UCH; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50053; UBIQUITIN_2; 1.
DR PROSITE; PS00972; USP_1; 1.
DR PROSITE; PS50235; USP_3; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022807};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000001645};
KW Thiol protease {ECO:0000256|ARBA:ARBA00022807};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 876..955
FT /note="Ubiquitin-like"
FT /evidence="ECO:0000259|PROSITE:PS50053"
FT DOMAIN 1604..1828
FT /note="USP"
FT /evidence="ECO:0000259|PROSITE:PS50235"
FT REGION 1044..1065
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1828 AA; 204950 MW; F22F907073C99161 CRC64;
VAPNKGQGLL LLCATSNGTW KAELQPSASS FYSQKNDENG NCSGEGIEFP TTNLYELESR
VLTDHWSIPY KREESLGKCL IASTYLARLG LSDSDENCKR FMDRCMPEAF KKLLTSSAVH
KWGTEIHEGI YNMLMLLVDL VAERVKQDPI PVGLLGVLTM AFNPDNEYHF KNRMKVCQRN
WAEVFGEGNM HAVSPISTFQ KVSTGLKPFA ELGGFSAIQS KLNSEDIELG AISALVQPFG
VCAEYLNSSV VQPMLDPVIH KMIKYVQNVE EKDLKDKRLV SIPELLSGIK LLCMRFQPDL
VTAVDDLRLD ILLRMLKSPH FSAKMNSLKE VTKLIEDSTV SKSVKNAIDT DRLLNWLVEN
SVLSIALEGN IDQAQYCDRI KGIIELLGSK LSLDELTKIW RIQSGQSSTV IENIHTIIAA
AAVKFSSDQL NHLFVLIQKS WETESDRVRQ KLLSLIGRIG REARVETTTG KVLEVLWELA
HLPTLPCSLI QQALEEHLTI LSDAYAVKEA IKRSYIIKCI EDIKRVGLLF YLLQNESSQH
NNPQFVWVVP ALRQLHEITR SFIKQTYQKQ DKSIIQDLKK NFEIVKLVTG SLISCHRLAA
SVAGPGGLVG ATLVDGRYTY REYLEAHLKF LAFFLQEATL YLGWNRAREI WECLVTGQDV
CELDREMCFE WFTKGQHDLE SDVQQQLFKE KILKLESYEI TMNGFSLFKT FFENVNLCDH
RLKRQGTQLS VEKLELIGMD FIWKIAMESP DEEIANEAIQ LIINYSYINL TPRLKKDSVS
LHKKFIADCY TRLEAASSAL GGPTLTHAVT RATKMLTATA MPTVATSVQS PYRSTKLVII
ERLLLLAERY VITIEDLYSV PRTILPHGAS FHGHLLTLNV TYESTKDTFT IEAHSNETVG
SIRWKIAKML NSPVDNIQIF ANDSLLTVNK DQKLLHQLGF SDEQVLTVKT SGSGTPSGSS
ADSSTSSSNS SSVFSSSYAM EQEKSLPGVV MALVCNVFDM LYQLANLEEP RITLRVRKLL
LLIPTDPAIQ EALDQLDSLG RKKTLLSESG SQSSKSPSLS SKHQHQPSAS SILESLFRSF
APGMSTFRVL YNLEVLSSKL MPTADDEMAR NCAKSFCENF LRAGGLSLVV NVMQRDSIPS
EVDYETRQGV YSICLQLARF LLVGQTMPTL LDEDFIKDGV EALSSRPFRN VSRQASRQMS
ICGTPEKSSY RQLSVSDRSS IRVEEIIPAA RVAIQTMEVN DFTSTVACFM RLSWAAAAGR
LDLVGSSQPI KENNTLFPAG IRNRLSSSGS NCSSGSEGEP TALHAGICVR QQSVSTKDAL
IAGEALSLLV TCLQLRSQQL GSFYNLPCVA DFIIDILLGS PSAEIRRVAC DQLYTLSQTD
TSTHPDVQKP NQFLLSVILG AQLPLWSPTS IMRGINQRLL SQCTEYFDLR CQLLDDLTSS
EMEQLKISPA AMLEDEITWL ENFEPNRTAE CETSEADNIL LAGHLRLIKT LLSLCGAEKE
MVGSSLIKPL LDDFLFRASR IILNSHSPAG SAAISQQDFH PKCSTADSRL AAYEVLVMLA
NSSPSNLQLI TKELLSMHHQ CDPALTKEFD YLPPVDSRSI SGFVGLKNGG ATCYMNAVFQ
QLYMQPGLPE ALLSIDDDTD NPDDNVFYQV QSLFGHLMES KLQYYVPENF WKIFKMWNKE
LYVREQQDAY EFFTSLIDQM DEYLKVKSSG IFFPIYMHFF FXXXXXXXXX XXXXXXXXXX
XXXXXXXXXX XXXXXKHLIF YFSIVFGHEA GEKLSSDYKL FSVLGEIMSI KNTISSAKQN
ENHPQRLKCS HIPHCFAYFK EHDHLLIY
//
