ID G1NGY6_MELGA Unreviewed; 696 AA.
AC G1NGY6;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 2.
DT 27-MAR-2024, entry version 76.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMGAP00000012397.2};
GN Name=PTPRE {ECO:0000313|Ensembl:ENSMGAP00000012397.2};
OS Meleagris gallopavo (Wild turkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Meleagridinae; Meleagris.
OX NCBI_TaxID=9103 {ECO:0000313|Ensembl:ENSMGAP00000012397.2, ECO:0000313|Proteomes:UP000001645};
RN [1] {ECO:0000313|Ensembl:ENSMGAP00000012397.2, ECO:0000313|Proteomes:UP000001645}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20838655; DOI=10.1371/journal.pbio.1000475;
RA Dalloul R.A., Long J.A., Zimin A.V., Aslam L., Beal K., Blomberg L.A.,
RA Bouffard P., Burt D.W., Crasta O., Crooijmans R.P., Cooper K.,
RA Coulombe R.A., De S., Delany M.E., Dodgson J.B., Dong J.J., Evans C.,
RA Frederickson K.M., Flicek P., Florea L., Folkerts O., Groenen M.A.,
RA Harkins T.T., Herrero J., Hoffmann S., Megens H.J., Jiang A., de Jong P.,
RA Kaiser P., Kim H., Kim K.W., Kim S., Langenberger D., Lee M.K., Lee T.,
RA Mane S., Marcais G., Marz M., McElroy A.P., Modise T., Nefedov M.,
RA Notredame C., Paton I.R., Payne W.S., Pertea G., Prickett D., Puiu D.,
RA Qioa D., Raineri E., Ruffier M., Salzberg S.L., Schatz M.C., Scheuring C.,
RA Schmidt C.J., Schroeder S., Searle S.M., Smith E.J., Smith J.,
RA Sonstegard T.S., Stadler P.F., Tafer H., Tu Z.J., Van Tassell C.P.,
RA Vilella A.J., Williams K.P., Yorke J.A., Zhang L., Zhang H.B., Zhang X.,
RA Zhang Y., Reed K.M.;
RT "Multi-platform next-generation sequencing of the domestic turkey
RT (Meleagris gallopavo): genome assembly and analysis.";
RL PLoS Biol. 8:E1000475-E1000475(2010).
RN [2] {ECO:0000313|Ensembl:ENSMGAP00000012397.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_010713134.1; XM_010714832.2.
DR RefSeq; XP_010713135.1; XM_010714833.2.
DR AlphaFoldDB; G1NGY6; -.
DR Ensembl; ENSMGAT00000013287.2; ENSMGAP00000012397.2; ENSMGAG00000011786.2.
DR GeneID; 100545838; -.
DR KEGG; mgp:100545838; -.
DR CTD; 5791; -.
DR GeneTree; ENSGT00940000156570; -.
DR HOGENOM; CLU_001645_8_2_1; -.
DR TreeFam; TF351829; -.
DR Proteomes; UP000001645; Chromosome 8.
DR Bgee; ENSMGAG00000011786; Expressed in brain and 14 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR CDD; cd14620; R-PTPc-E-1; 1.
DR CDD; cd14622; R-PTPc-E-2; 1.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 2.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR000242; PTP_cat.
DR InterPro; IPR016130; Tyr_Pase_AS.
DR InterPro; IPR003595; Tyr_Pase_cat.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR PANTHER; PTHR19134; RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE; 1.
DR PANTHER; PTHR19134:SF499; RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE EPSILON; 1.
DR Pfam; PF00102; Y_phosphatase; 2.
DR PRINTS; PR00700; PRTYPHPHTASE.
DR SMART; SM00194; PTPc; 2.
DR SMART; SM00404; PTPc_motif; 2.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 2.
DR PROSITE; PS00383; TYR_PHOSPHATASE_1; 2.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 2.
DR PROSITE; PS50055; TYR_PHOSPHATASE_PTP; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001645};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..696
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5032925466"
FT TRANSMEM 46..68
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 134..392
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50055"
FT DOMAIN 312..383
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
FT DOMAIN 424..685
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50055"
FT DOMAIN 601..676
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
SQ SEQUENCE 696 AA; 80330 MW; 2CEE016796D3D860 CRC64;
MEQPCPCLLL CVSFLFVRAL PPNGTELPKP TSTTNSTEEN NLHKDLLTSM LILLLVFIIF
ILLAGYFFRF RRHRKAVVSS GDKKMPNGIL EEQEQQRVML LSRSPSGPKK YFAIPVENLE
EEIRIRSADE GKLFREEFNS LTPGYVQGTF EMANKEENRE KNRYPNILPY DHSRVILTQV
DGVSPSDYIN ASYIDGYKEK NKFIAAQGPK QETVNDFWRM VWEQKSAVIV MLTNLKERKE
DKCYQYWPDQ GCWTYGNIRV SVEDCIVLVD YTIRKFCVQS LQDGCKALRL VTQLHFTSWP
DFGVPFTPIG MLKFLKKVKA LNPALAGPIV VHCSAGVGRT GTFIVIDAMI DMMHAEQKVD
VFEFVSRIRN QRPQMVQTDM QYSFIYQALL EYYLYGDTEL DVSSLEKHLQ TSHSAAPNLV
KIGLEEEFKK LTNVRIMKEN MRTGNLPANM KKARVIQIIP YDFNRVILSM KRGQEYTDYI
NASFIDGYRQ KDYFIATQGP LPHTVEDFWR MVWEWKCHTI VMLTEVQERE QEKCFQYWPS
EGSVTHGEIT VEIKNDSLLD AISVRDFIVT YNQGNQEKQS RLVRQFHFHG WPEIGIPAEG
KGMIDLIAAV QKQQQQTGNH PITVHCSAGA GRTGTFIALS NILERVKAEG LLDVFQAVKS
LRLQRPHMVQ TLEQYEFCYR VVQDFIDIFS DYANFK
//
