ID G1NK45_MELGA Unreviewed; 666 AA.
AC G1NK45;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 3.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Tigger transposable element derived 5 {ECO:0000313|Ensembl:ENSMGAP00000013761.3};
GN Name=TIGD5 {ECO:0000313|Ensembl:ENSMGAP00000013761.3};
OS Meleagris gallopavo (Wild turkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Meleagridinae; Meleagris.
OX NCBI_TaxID=9103 {ECO:0000313|Ensembl:ENSMGAP00000013761.3, ECO:0000313|Proteomes:UP000001645};
RN [1] {ECO:0000313|Ensembl:ENSMGAP00000013761.3, ECO:0000313|Proteomes:UP000001645}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20838655; DOI=10.1371/journal.pbio.1000475;
RA Dalloul R.A., Long J.A., Zimin A.V., Aslam L., Beal K., Blomberg L.A.,
RA Bouffard P., Burt D.W., Crasta O., Crooijmans R.P., Cooper K.,
RA Coulombe R.A., De S., Delany M.E., Dodgson J.B., Dong J.J., Evans C.,
RA Frederickson K.M., Flicek P., Florea L., Folkerts O., Groenen M.A.,
RA Harkins T.T., Herrero J., Hoffmann S., Megens H.J., Jiang A., de Jong P.,
RA Kaiser P., Kim H., Kim K.W., Kim S., Langenberger D., Lee M.K., Lee T.,
RA Mane S., Marcais G., Marz M., McElroy A.P., Modise T., Nefedov M.,
RA Notredame C., Paton I.R., Payne W.S., Pertea G., Prickett D., Puiu D.,
RA Qioa D., Raineri E., Ruffier M., Salzberg S.L., Schatz M.C., Scheuring C.,
RA Schmidt C.J., Schroeder S., Searle S.M., Smith E.J., Smith J.,
RA Sonstegard T.S., Stadler P.F., Tafer H., Tu Z.J., Van Tassell C.P.,
RA Vilella A.J., Williams K.P., Yorke J.A., Zhang L., Zhang H.B., Zhang X.,
RA Zhang Y., Reed K.M.;
RT "Multi-platform next-generation sequencing of the domestic turkey
RT (Meleagris gallopavo): genome assembly and analysis.";
RL PLoS Biol. 8:E1000475-E1000475(2010).
RN [2] {ECO:0000313|Ensembl:ENSMGAP00000013761.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00320}.
CC -!- SIMILARITY: Belongs to the tigger transposable element derived protein
CC family. {ECO:0000256|ARBA:ARBA00010881}.
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DR RefSeq; XP_003205381.3; XM_003205333.3.
DR AlphaFoldDB; G1NK45; -.
DR Ensembl; ENSMGAT00000014676.3; ENSMGAP00000013761.3; ENSMGAG00000013045.3.
DR GeneID; 100542894; -.
DR KEGG; mgp:100542894; -.
DR CTD; 84948; -.
DR GeneTree; ENSGT00940000154420; -.
DR HOGENOM; CLU_018294_1_1_1; -.
DR InParanoid; G1NK45; -.
DR TreeFam; TF338616; -.
DR Proteomes; UP000001645; Chromosome 3.
DR Bgee; ENSMGAG00000013045; Expressed in pectoralis major and 12 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004875; DDE_SF_endonuclease_dom.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR006600; HTH_CenpB_DNA-bd_dom.
DR InterPro; IPR007889; HTH_Psq.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR19303:SF56; TIGGER TRANSPOSABLE ELEMENT-DERIVED PROTEIN 5; 1.
DR PANTHER; PTHR19303; TRANSPOSON; 1.
DR Pfam; PF04218; CENP-B_N; 1.
DR Pfam; PF03184; DDE_1; 1.
DR Pfam; PF03221; HTH_Tnp_Tc5; 1.
DR SMART; SM00674; CENPB; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 2.
DR PROSITE; PS51253; HTH_CENPB; 1.
DR PROSITE; PS50960; HTH_PSQ; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00320};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00320};
KW Reference proteome {ECO:0000313|Proteomes:UP000001645}.
FT DOMAIN 121..172
FT /note="HTH psq-type"
FT /evidence="ECO:0000259|PROSITE:PS50960"
FT DOMAIN 186..259
FT /note="HTH CENPB-type"
FT /evidence="ECO:0000259|PROSITE:PS51253"
FT DNA_BIND 148..168
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00320"
FT REGION 1..84
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 518..542
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 570..617
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 27..62
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 69..84
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 575..591
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 666 AA; 69466 MW; ABC5535C5C7B6506 CRC64;
MAGEEEEVGG GAAGMAGGRQ GGGGGGGGGG SSSSSSNGGG TSNGRGTSNG GGSGTSNGGD
ISNGGGGGGI SNGGGSSSGS GTSSAGGICN GGGTSNGCVG GGTSNSSSGG GCSNGGGVGV
SMKMAFRRAY SIKDKLHAIE RVKKGERQAS VCRAFGVPGG TLRGWLKDEA KLRWFLEQLG
GEVGTQRKKM RLANEEEIDR AVYAWFLALR QHGVPLSGPL IQAQAEAFAR QIYGPECTFK
ASHGWFWRWQ KRHGISSQRI YGEGALHAEP ERTSIAHPNL PPTPGSDTGG YGDEQIYNAN
ITGLYWKLLP GRTAPRQRVT VLLAANLTGT HKLKPLVVGG LRDPPSLCHH NQEKFPAGYR
YSPEARLGPA LLRVWFFEDF VPCVKRYLRR SCLQQKAVLL LTAPPTSGGR HEDLPQLQTP
DGSIRALFLS KSPTGSSSTG GGSRIPAPLE QGVVSAFKQL YKRELLRLAI SAGGPVDFAR
SFLLKDMLYL AGLSWDLIPP NAIEKCWLLG LRAAFEPQPG EEEQGGGGGD CTTGEEGNGD
GKVFSDLTQL AALAYKRLAP EEVANWLHLD DMAPGTGEDD EDEDAMEEGP GGCKEEEERA
GGGGNGAGGG GSPLMPTAHE AIRGLETALR WLEGQDPRRV GPLKLVQLRS LISMAQRLHH
GSSPDP
//
