ID G1NS32_MELGA Unreviewed; 72 AA.
AC G1NS32;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 3.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 {ECO:0000256|ARBA:ARBA00018681};
DE AltName: Full=Complex I-B15 {ECO:0000256|ARBA:ARBA00030212};
DE AltName: Full=NADH-ubiquinone oxidoreductase B15 subunit {ECO:0000256|ARBA:ARBA00030987};
OS Meleagris gallopavo (Wild turkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Meleagridinae; Meleagris.
OX NCBI_TaxID=9103 {ECO:0000313|Ensembl:ENSMGAP00000017011.3, ECO:0000313|Proteomes:UP000001645};
RN [1] {ECO:0000313|Ensembl:ENSMGAP00000017011.3, ECO:0000313|Proteomes:UP000001645}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20838655; DOI=10.1371/journal.pbio.1000475;
RA Dalloul R.A., Long J.A., Zimin A.V., Aslam L., Beal K., Blomberg L.A.,
RA Bouffard P., Burt D.W., Crasta O., Crooijmans R.P., Cooper K.,
RA Coulombe R.A., De S., Delany M.E., Dodgson J.B., Dong J.J., Evans C.,
RA Frederickson K.M., Flicek P., Florea L., Folkerts O., Groenen M.A.,
RA Harkins T.T., Herrero J., Hoffmann S., Megens H.J., Jiang A., de Jong P.,
RA Kaiser P., Kim H., Kim K.W., Kim S., Langenberger D., Lee M.K., Lee T.,
RA Mane S., Marcais G., Marz M., McElroy A.P., Modise T., Nefedov M.,
RA Notredame C., Paton I.R., Payne W.S., Pertea G., Prickett D., Puiu D.,
RA Qioa D., Raineri E., Ruffier M., Salzberg S.L., Schatz M.C., Scheuring C.,
RA Schmidt C.J., Schroeder S., Searle S.M., Smith E.J., Smith J.,
RA Sonstegard T.S., Stadler P.F., Tafer H., Tu Z.J., Van Tassell C.P.,
RA Vilella A.J., Williams K.P., Yorke J.A., Zhang L., Zhang H.B., Zhang X.,
RA Zhang Y., Reed K.M.;
RT "Multi-platform next-generation sequencing of the domestic turkey
RT (Meleagris gallopavo): genome assembly and analysis.";
RL PLoS Biol. 8:E1000475-E1000475(2010).
RN [2] {ECO:0000313|Ensembl:ENSMGAP00000017011.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Accessory subunit of the mitochondrial membrane respiratory
CC chain NADH dehydrogenase (Complex I), that is believed not to be
CC involved in catalysis. Complex I functions in the transfer of electrons
CC from NADH to the respiratory chain. The immediate electron acceptor for
CC the enzyme is believed to be ubiquinone.
CC {ECO:0000256|ARBA:ARBA00003195}.
CC -!- SUBUNIT: Complex I is composed of 45 different subunits.
CC {ECO:0000256|ARBA:ARBA00011533}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC {ECO:0000256|ARBA:ARBA00004298}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004298}; Matrix side
CC {ECO:0000256|ARBA:ARBA00004298}.
CC -!- SIMILARITY: Belongs to the complex I NDUFB4 subunit family.
CC {ECO:0000256|ARBA:ARBA00007260}.
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DR AlphaFoldDB; G1NS32; -.
DR Ensembl; ENSMGAT00000017985.3; ENSMGAP00000017011.3; ENSMGAG00000016069.3.
DR GeneTree; ENSGT00990000213302; -.
DR HOGENOM; CLU_2837869_0_0_1; -.
DR InParanoid; G1NS32; -.
DR Proteomes; UP000001645; Chromosome 1.
DR Bgee; ENSMGAG00000016069; Expressed in pectoralis major and 17 other cell types or tissues.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR009866; NADH_UbQ_OxRdtase_NDUFB4_su.
DR PANTHER; PTHR15469:SF0; NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 4; 1.
DR PANTHER; PTHR15469; NADH-UBIQUINONE OXIDOREDUCTASE B15 SUBUNIT; 1.
DR Pfam; PF07225; NDUF_B4; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001645};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 27..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 72 AA; 7980 MW; DC175BF7C9665C74 CRC64;
EDPALLRWDY ARTHNVYPTF RPTPKTSFLG AVFAIGPILF WIAVFKTERV SSAGGVEHQG
TPGCKTQVCL KT
//