ID G1NZ34_MYOLU Unreviewed; 482 AA.
AC G1NZ34;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Transcription factor CP2 like 1 {ECO:0000313|Ensembl:ENSMLUP00000002701.2};
GN Name=TFCP2L1 {ECO:0000313|Ensembl:ENSMLUP00000002701.2};
OS Myotis lucifugus (Little brown bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=59463 {ECO:0000313|Ensembl:ENSMLUP00000002701.2, ECO:0000313|Proteomes:UP000001074};
RN [1] {ECO:0000313|Ensembl:ENSMLUP00000002701.2, ECO:0000313|Proteomes:UP000001074}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSMLUP00000002701.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU01313}.
CC -!- SIMILARITY: Belongs to the grh/CP2 family. CP2 subfamily.
CC {ECO:0000256|ARBA:ARBA00010852}.
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DR EMBL; AAPE02048826; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAPE02048827; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAPE02048828; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAPE02048829; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAPE02048830; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1NZ34; -.
DR STRING; 59463.ENSMLUP00000002701; -.
DR Ensembl; ENSMLUT00000002971.2; ENSMLUP00000002701.2; ENSMLUG00000002967.2.
DR eggNOG; KOG4091; Eukaryota.
DR GeneTree; ENSGT00940000159158; -.
DR HOGENOM; CLU_015127_2_0_1; -.
DR InParanoid; G1NZ34; -.
DR OMA; QDESCFT; -.
DR TreeFam; TF314132; -.
DR Proteomes; UP000001074; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:Ensembl.
DR CDD; cd09590; SAM_LBP9; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR007604; CP2.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR041418; SAM_3.
DR InterPro; IPR040167; TF_CP2-like.
DR InterPro; IPR037598; TFCP2L1_SAM.
DR PANTHER; PTHR11037; TRANSCRIPTION FACTOR CP2; 1.
DR PANTHER; PTHR11037:SF18; TRANSCRIPTION FACTOR CP2-LIKE PROTEIN 1; 1.
DR Pfam; PF04516; CP2; 1.
DR Pfam; PF18016; SAM_3; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR PROSITE; PS51968; GRH_CP2_DB; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU01313};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU01313};
KW Reference proteome {ECO:0000313|Proteomes:UP000001074}.
FT DOMAIN 46..281
FT /note="Grh/CP2 DB"
FT /evidence="ECO:0000259|PROSITE:PS51968"
FT REGION 219..248
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 272..297
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 220..245
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 482 AA; 54700 MW; 22F012CE6DBE0A5B CRC64;
CWFWHTQPEH YNQHGSGATC GYLSDVLALP IFKQEEPQLS PENEARLPPL QYVLCAATSP
AVKLHEETLT YLNQGQSYEI RLLENRKLGD FQDLNTKYVK SIIRVVFHDR RLQYTEHQQL
EGWRWSRPGD RILDLGVPVS TEMVPAFWSP SRLAHVTWMP GPAPRLPSQV HCISTEFTPR
KHGGEKGVPF RVQIDTFKQN ENGEYTEHLH SASCQIKVFK PKGADRKQKT DREKMEKRTA
QEKEKYQPSY ETTILTECSP WPDVAYQVNS APSPSYNGSP NSFGLGEGST SPTHSHPLET
LPMGSDHLLP SASIQDAQQW LHRHRFSQFC RLFASFSGAD LLKMSRDDLV QICGPADGIR
LFNAIKGRNV RPKMTIYVCQ EVEQSRAPLQ QKRDGGGDSG LCVYHAIFLE ELTTLELIEK
IANLYSISPQ HIHRVYRQGP TGIHVVVSNE MVQNFQDESC FVLSTLKAES SDGYHIILKC
GL
//
