ID G1P2S7_MYOLU Unreviewed; 916 AA.
AC G1P2S7;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Ankyrin repeat and MYND domain containing 1 {ECO:0000313|Ensembl:ENSMLUP00000004178.2};
GN Name=ANKMY1 {ECO:0000313|Ensembl:ENSMLUP00000004178.2};
OS Myotis lucifugus (Little brown bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=59463 {ECO:0000313|Ensembl:ENSMLUP00000004178.2, ECO:0000313|Proteomes:UP000001074};
RN [1] {ECO:0000313|Ensembl:ENSMLUP00000004178.2, ECO:0000313|Proteomes:UP000001074}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSMLUP00000004178.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAPE02004515; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAPE02004516; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAPE02004517; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAPE02004518; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1P2S7; -.
DR STRING; 59463.ENSMLUP00000004178; -.
DR Ensembl; ENSMLUT00000004593.2; ENSMLUP00000004178.2; ENSMLUG00000004589.2.
DR eggNOG; ENOG502QQJP; Eukaryota.
DR GeneTree; ENSGT00460000041630; -.
DR InParanoid; G1P2S7; -.
DR OMA; IYIRWLQ; -.
DR TreeFam; TF328860; -.
DR Proteomes; UP000001074; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 6.10.140.2220; -; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR Gene3D; 2.20.110.10; Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR003409; MORN.
DR InterPro; IPR002893; Znf_MYND.
DR PANTHER; PTHR15897; ANKYRIN REPEAT AND MYND DOMAIN PROTEIN 1; 1.
DR PANTHER; PTHR15897:SF2; ANKYRIN REPEAT AND MYND DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF13637; Ank_4; 1.
DR Pfam; PF02493; MORN; 2.
DR Pfam; PF01753; zf-MYND; 1.
DR SMART; SM00248; ANK; 4.
DR SMART; SM00698; MORN; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 2.
DR SUPFAM; SSF82185; Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain; 1.
DR SUPFAM; SSF144232; HIT/MYND zinc finger-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 2.
DR PROSITE; PS50088; ANK_REPEAT; 3.
DR PROSITE; PS01360; ZF_MYND_1; 1.
DR PROSITE; PS50865; ZF_MYND_2; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001074};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00134}.
FT REPEAT 283..315
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 630..661
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 667..699
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 853..893
FT /note="MYND-type"
FT /evidence="ECO:0000259|PROSITE:PS50865"
SQ SEQUENCE 916 AA; 103810 MW; DB22F4445555415F CRC64;
MKLGYGEFSW PTGESYHGQF YRDHRHGFGT YMWPDGSSFT GMFYLSFREG YGTMYMKTRL
FQGLYKADER FGPGIETYPD GSQEVGLWFR EHLIKLCTEI PCSVSISSYP EFQGFLTHSP
ARISLSEEET MHWDLQEERD PFFYNYKQFL LNDDLTLPPD VYLYSTDNTH MPITRSFRRD
LDSRIFLHDI PPFVEDGEPW FIKNETPLMV KIQKHTYKFR NKKEHSSWNM GAILEGDRSG
FACRGPKERL AKEMILKAEE GNYDWIYGIL RDNLASPDVA DARGYTVLAA AAIHCHINII
NLLLDNGADV NKCTDEGLTP LNMCFLLYYP ATSFRPNIAE RTVPEPQEKA FTQPILCPPQ
TEFFSVSSVF LGQKLFTTIT TDFQGLESRQ TPRPPNLKYL QKKWESTLPR GSVSISDQGQ
ELEDVLESLD RCTPCSSTET NFESNHCVQN YSIRLSWNML EKSARAYSML KVPSPEAISD
KGTMRQMAWT MTKVSHRVSI TFLLPWEGMF SSACALSLRV LDWHMGSGHH TGVHTLSPPY
TQHGCTLPPS SQSRTHVHLG TISVRQSVYM TKSRHHRSTR RIPLGGSGAA SVYMWCGVQP
EMLPSSMKLN NEVGPPRVYS SVNMSVPEEG GRTPLHVACE REDNYRYARD VVHLLLSNRA
NSSLLWGGHS PLSLSIASGN DLIVKELLTN GADPNLPLTK GLGNALCVAC DIAYEHRRSV
NSRLGLIDLL INYGADILAP VTLTQGDKVA VGTAVDYGYF KFFQDRKIAH CPFHTLMPAE
RETFVARKRL LEYMGFQLRS AIMAKESLWD PKVLCLSKKA QMIPCHKLKQ RDPSTPKDPQ
LEELEQTPFF KFCYQCGRSI GVRLLPCSRC YGILTCSKSC KTKAWADFHG RDCGTLAAIG
PHGSCRGPVW RIHWTP
//
