ID G1P9H6_MYOLU Unreviewed; 465 AA.
AC G1P9H6;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=Golgi associated PDZ and coiled-coil motif containing {ECO:0000313|Ensembl:ENSMLUP00000006884.2};
GN Name=GOPC {ECO:0000313|Ensembl:ENSMLUP00000006884.2};
OS Myotis lucifugus (Little brown bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=59463 {ECO:0000313|Ensembl:ENSMLUP00000006884.2, ECO:0000313|Proteomes:UP000001074};
RN [1] {ECO:0000313|Ensembl:ENSMLUP00000006884.2, ECO:0000313|Proteomes:UP000001074}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSMLUP00000006884.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAPE02018727; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAPE02018728; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1P9H6; -.
DR STRING; 59463.ENSMLUP00000006884; -.
DR Ensembl; ENSMLUT00000007540.2; ENSMLUP00000006884.2; ENSMLUG00000007543.2.
DR eggNOG; KOG3528; Eukaryota.
DR GeneTree; ENSGT00940000156535; -.
DR HOGENOM; CLU_045744_0_0_1; -.
DR InParanoid; G1P9H6; -.
DR OMA; QCNLRQE; -.
DR TreeFam; TF317932; -.
DR Proteomes; UP000001074; Unassembled WGS sequence.
DR GO; GO:0005794; C:Golgi apparatus; IEA:Ensembl.
DR GO; GO:0016020; C:membrane; IEA:Ensembl.
DR GO; GO:0032991; C:protein-containing complex; IEA:Ensembl.
DR GO; GO:0030140; C:trans-Golgi network transport vesicle; IEA:Ensembl.
DR GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR GO; GO:0140313; F:molecular sequestering activity; IEA:Ensembl.
DR GO; GO:0044325; F:transmembrane transporter binding; IEA:Ensembl.
DR GO; GO:2000009; P:negative regulation of protein localization to cell surface; IEA:Ensembl.
DR CDD; cd14686; bZIP; 1.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR InterPro; IPR038879; GOPC.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR PANTHER; PTHR16528; GOLGI-ASSOCIATED PDZ AND COILED-COIL MOTIF-CONTAINING; 1.
DR PANTHER; PTHR16528:SF2; GOLGI-ASSOCIATED PDZ AND COILED-COIL MOTIF-CONTAINING PROTEIN; 1.
DR Pfam; PF00595; PDZ; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000001074}.
FT DOMAIN 291..374
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 423..450
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 85..119
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 158..202
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 430..450
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 465 AA; 51022 MW; C8FA57DF1DFD57AF CRC64;
MSAGGPCPAG AGGGPGGASC AVGVSPGGVS MFRWLEVLEK EFDKAFVDVD LLLGEIDPDQ
ADITYEGRQK MTSLSSCFAQ LCHKVQTVSQ INHKLEAQLV DLKSELTETQ AEKVVLEKEV
HDQLLQLHSV QLQLHAKTGQ SVDSGTIKAK LLKSVPSVEE LERELEANKK EKMKEAQLEA
EVKLLRKENE ALRRHIAVLQ AEVYGARLAA KYLDKELAGR VQQIQLLGRD MKGPAHDKLW
NQLEAEIHLH RHKTVIRACR GRNDLKRPMQ APPGHDQDSL KKSQGVGPIR KVLLLKEDYE
GLGISITGGK EHGVPILISE IQPGQPADRC GGLHVGDAIL AVNGVNLRDT KHKEAVTILS
QQRGEIEFEV VYVAPEVDSD DENVEYEDES GHRYRLYLDE LEGGSNPGAT CKDTSGEVKV
LQGFNKKSVT DGHENGDLGT SRETPLEDSA AKLDDLHSLY QRKSC
//
