ID G1PBY1_MYOLU Unreviewed; 474 AA.
AC G1PBY1;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSMLUP00000007897.2};
GN Name=CADM1 {ECO:0000313|Ensembl:ENSMLUP00000007897.2};
OS Myotis lucifugus (Little brown bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=59463 {ECO:0000313|Ensembl:ENSMLUP00000007897.2, ECO:0000313|Proteomes:UP000001074};
RN [1] {ECO:0000313|Ensembl:ENSMLUP00000007897.2, ECO:0000313|Proteomes:UP000001074}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSMLUP00000007897.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAPE02041150; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAPE02041151; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAPE02041152; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAPE02041153; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAPE02041154; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAPE02041155; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAPE02041156; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1PBY1; -.
DR STRING; 59463.ENSMLUP00000007897; -.
DR Ensembl; ENSMLUT00000008663.2; ENSMLUP00000007897.2; ENSMLUG00000008661.2.
DR eggNOG; ENOG502R1KU; Eukaryota.
DR GeneTree; ENSGT00940000156093; -.
DR HOGENOM; CLU_047574_2_1_1; -.
DR InParanoid; G1PBY1; -.
DR OMA; TYDRMYT; -.
DR TreeFam; TF334317; -.
DR Proteomes; UP000001074; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0005102; F:signaling receptor binding; IEA:Ensembl.
DR GO; GO:0008037; P:cell recognition; IEA:Ensembl.
DR GO; GO:0051606; P:detection of stimulus; IEA:Ensembl.
DR GO; GO:0001819; P:positive regulation of cytokine production; IEA:Ensembl.
DR GO; GO:0042271; P:susceptibility to natural killer cell mediated cytotoxicity; IEA:Ensembl.
DR CDD; cd05883; IgI_2_Necl-2; 1.
DR CDD; cd05881; IgV_1_Necl-2; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR InterPro; IPR003585; Neurexin-like.
DR PANTHER; PTHR45889:SF2; CELL ADHESION MOLECULE 1; 1.
DR PANTHER; PTHR45889; IG-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00294; 4.1m; 1.
DR SMART; SM00409; IG; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
DR PROSITE; PS50835; IG_LIKE; 3.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001074};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..46
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 47..474
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003417655"
FT TRANSMEM 407..427
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 42..141
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 146..240
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 245..333
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 474 AA; 51816 MW; 276FC02838FBDD7A CRC64;
MASAVLPSGS QCAAAAAAVA AAPPGLRLRL LLLLLSAAAL IPTGDGQNLF TKDVTVIEGE
VATISCQVNK SDDSVIQLLN PNRQTIYFRD FRPLKDSRFQ LLNFSSSELK VSLTNVSISD
EGRYFCQLYT DPPQESYTTI TVLVPPRNLV IDIQKDTAVE GEEIEVNCTA MASKPATTIR
WFKGNTELKG KSEVEEWSDM YTVTSQLMLK VRREDDGVPV ICQVEHPAVT GNLQTQRYLE
VQYKPRVHIQ MTYPLQGLTR EGDALELTCE VSGKPQDWPV TLSCWKVCFS FPQRQVTTGN
IFVSKLFLLL KGGTYRCEAS NVVGKAHSDY TLYVYDPPTT IPPPTTTTTT TTTTTTILTI
IPDTTATTEP AVHGLTQLPN SAEELDSEDL ADSRAGEEGS IRAVDHAVIG GVVAVVVFAM
LCLLIILGRY FARHKGTYFT HEAKGADDAA DADTAIINAE GGQNNSEEKK EYFI
//
