ID G1PCP9_MYOLU Unreviewed; 464 AA.
AC G1PCP9;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Sushi repeat containing protein X-linked {ECO:0000313|Ensembl:ENSMLUP00000008202.2};
GN Name=SRPX {ECO:0000313|Ensembl:ENSMLUP00000008202.2};
OS Myotis lucifugus (Little brown bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=59463 {ECO:0000313|Ensembl:ENSMLUP00000008202.2, ECO:0000313|Proteomes:UP000001074};
RN [1] {ECO:0000313|Ensembl:ENSMLUP00000008202.2, ECO:0000313|Proteomes:UP000001074}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSMLUP00000008202.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
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DR EMBL; AAPE02021522; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1PCP9; -.
DR STRING; 59463.ENSMLUP00000008202; -.
DR Ensembl; ENSMLUT00000009001.2; ENSMLUP00000008202.2; ENSMLUG00000008997.2.
DR eggNOG; ENOG502QVU2; Eukaryota.
DR GeneTree; ENSGT00940000160302; -.
DR HOGENOM; CLU_047011_0_0_1; -.
DR InParanoid; G1PCP9; -.
DR OMA; RIQYTVY; -.
DR TreeFam; TF336515; -.
DR Proteomes; UP000001074; Unassembled WGS sequence.
DR CDD; cd00033; CCP; 3.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 3.
DR InterPro; IPR025232; DUF4174.
DR InterPro; IPR003410; HYR_dom.
DR InterPro; IPR043555; SRPX-like.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR PANTHER; PTHR46343; HYR DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46343:SF1; SUSHI REPEAT-CONTAINING PROTEIN SRPX; 1.
DR Pfam; PF13778; DUF4174; 1.
DR Pfam; PF02494; HYR; 1.
DR Pfam; PF00084; Sushi; 3.
DR SMART; SM00032; CCP; 3.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 3.
DR PROSITE; PS50825; HYR; 1.
DR PROSITE; PS50923; SUSHI; 3.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00302}; Reference proteome {ECO:0000313|Proteomes:UP000001074};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Sushi {ECO:0000256|ARBA:ARBA00022659, ECO:0000256|PROSITE-
KW ProRule:PRU00302}.
FT SIGNAL 1..35
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 36..464
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003417968"
FT DOMAIN 67..117
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 118..176
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 175..259
FT /note="HYR"
FT /evidence="ECO:0000259|PROSITE:PS50825"
FT DOMAIN 260..319
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DISULFID 147..174
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 290..317
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
SQ SEQUENCE 464 AA; 51643 MW; 4D97F685B2A59417 CRC64;
MGSGQRSPAR FTLRGPLSLH LFLLQFLFFF VVGSGDSPLE DDDMGYSHPR YKDTPWCSPV
KVKYGDVYCR APQGGYYTTA LGTRCDIRCQ KGYELHGSSP LICQSNKRWS HKVICKQKRC
PTLAMPANGG FKCVDGAYFN SRCEYYCSPG YTLKGERTVM CMDNKAWSGQ PASCVDMEPP
RIKCPSVKER MAEPNKLTVR VSWDTPEGRD TADGILTDVI LKGLPPGSNF PEGDHKIQYT
VYDRAENKGT CKFRVKVKVK RCGKLNAPEN GYMKCSSDGD NYGATCEFSC IGGYELQGSP
ARVCQSNLAW SGTEPTCAAM NINVGVRTAA ALLDQFYEKR RILIVSTPTA RNLLYRLQLG
MLQQAQCSLD LRHITVVELV GVFPALIGRI GAKIMPPALA LQLRLLLRIP LYSFSMVLVD
KHGMDKERYV SLVTPVALFN LIDTFPLRKE EMALQAEMGQ TCNT
//
