ID G1PDM7_MYOLU Unreviewed; 703 AA.
AC G1PDM7;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=FAST kinase domains 2 {ECO:0000313|Ensembl:ENSMLUP00000008581.2};
GN Name=FASTKD2 {ECO:0000313|Ensembl:ENSMLUP00000008581.2};
OS Myotis lucifugus (Little brown bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=59463 {ECO:0000313|Ensembl:ENSMLUP00000008581.2, ECO:0000313|Proteomes:UP000001074};
RN [1] {ECO:0000313|Ensembl:ENSMLUP00000008581.2, ECO:0000313|Proteomes:UP000001074}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSMLUP00000008581.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAPE02003241; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1PDM7; -.
DR STRING; 59463.ENSMLUP00000008581; -.
DR Ensembl; ENSMLUT00000009415.2; ENSMLUP00000008581.2; ENSMLUG00000009411.2.
DR eggNOG; ENOG502QVSD; Eukaryota.
DR GeneTree; ENSGT01030000234607; -.
DR HOGENOM; CLU_025270_0_0_1; -.
DR InParanoid; G1PDM7; -.
DR OMA; FEIRMDS; -.
DR TreeFam; TF352875; -.
DR Proteomes; UP000001074; Unassembled WGS sequence.
DR GO; GO:0042645; C:mitochondrial nucleoid; IEA:Ensembl.
DR GO; GO:0035770; C:ribonucleoprotein granule; IEA:Ensembl.
DR GO; GO:0019843; F:rRNA binding; IEA:Ensembl.
DR GO; GO:0006915; P:apoptotic process; IEA:Ensembl.
DR GO; GO:1902775; P:mitochondrial large ribosomal subunit assembly; IEA:Ensembl.
DR GO; GO:0032543; P:mitochondrial translation; IEA:Ensembl.
DR GO; GO:0070131; P:positive regulation of mitochondrial translation; IEA:Ensembl.
DR GO; GO:0044528; P:regulation of mitochondrial mRNA stability; IEA:InterPro.
DR GO; GO:0006396; P:RNA processing; IEA:Ensembl.
DR InterPro; IPR010622; FAST_Leu-rich.
DR InterPro; IPR013584; RAP.
DR PANTHER; PTHR21228:SF1; FAST KINASE DOMAIN-CONTAINING PROTEIN 2, MITOCHONDRIAL; 1.
DR PANTHER; PTHR21228; FAST LEU-RICH DOMAIN-CONTAINING; 1.
DR Pfam; PF06743; FAST_1; 1.
DR Pfam; PF08373; RAP; 1.
DR SMART; SM00952; RAP; 1.
DR PROSITE; PS51286; RAP; 1.
PE 4: Predicted;
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Reference proteome {ECO:0000313|Proteomes:UP000001074}.
FT DOMAIN 627..684
FT /note="RAP"
FT /evidence="ECO:0000259|PROSITE:PS51286"
FT REGION 114..140
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 119..140
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 703 AA; 80061 MW; 72FD2BA06975525D CRC64;
QLLGSASVES TMSNRAGSFL WNLRQFSALS PTSRTVRPNP LGFCRPEIVY SNWSPRNHPS
NDFASKTQSP IRYLFQDASV FKPGDDVFQT KGISPVTALP VNRFLCPRRL SFDSKQSPVP
EDGSKKMRFH HEASDEDVLT RETKPTPVNF KKLSQGNSLS DVLDAFASAP SFPSSNYFSA
MWTIAKRMSD DQRRFEKQLM FSHPAFTQLC EHMMREAKIM YCDHLLFSLY AIVRLGIPQN
TLLVQTLLRV VQERINECDE RCLSVLSIIL EAMEPCKNVD VLRSGLRILV DQQIWKIERV
FTLQAVMKSI GKDAPISLKK KLEMKALREL HRFSVLNSQR MFEVLAAMDH RSDVLLDECS
KMVIGNINGC PLKILINILQ SCRDLRYRNL YLFKGIADYV ATTFDVWKLR QVLFVLILFE
NLAFRHTDLM DLFMKKVVDE RGFLNMKSIV SILHVYASLN HLHGGPAREE WFLDAMGAAL
TGYLHHISSE NLLNAVCSFC LMNHFPLAPI NQLLQKDIID ELLMSDNKER NIYKLQILAA
CLKLDDVPCH KAVDLVLPSL PPAPLYPNAK VAEVLSSLLG EGYFLENVQL PHNHHIDFEI
RMDSNRSEVL PLSDANVVTS ATDIQRVAVL CVPRSTYCLD LTHPRGFLAT KMRHLKVMGF
HVILVNNWEM EKLEMKEAVT FLKSQIYSTE SPPTADVNFQ STC
//
