ID G1PGQ6_MYOLU Unreviewed; 702 AA.
AC G1PGQ6;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=CAP-Gly domain containing linker protein family member 4 {ECO:0000313|Ensembl:ENSMLUP00000009831.2};
GN Name=CLIP4 {ECO:0000313|Ensembl:ENSMLUP00000009831.2};
OS Myotis lucifugus (Little brown bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=59463 {ECO:0000313|Ensembl:ENSMLUP00000009831.2, ECO:0000313|Proteomes:UP000001074};
RN [1] {ECO:0000313|Ensembl:ENSMLUP00000009831.2, ECO:0000313|Proteomes:UP000001074}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSMLUP00000009831.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAPE02028458; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAPE02028459; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1PGQ6; -.
DR STRING; 59463.ENSMLUP00000009831; -.
DR Ensembl; ENSMLUT00000010784.2; ENSMLUP00000009831.2; ENSMLUG00000010758.2.
DR eggNOG; KOG0241; Eukaryota.
DR eggNOG; KOG4568; Eukaryota.
DR GeneTree; ENSGT00940000157706; -.
DR HOGENOM; CLU_023687_1_0_1; -.
DR InParanoid; G1PGQ6; -.
DR OMA; HADFLPD; -.
DR TreeFam; TF326096; -.
DR Proteomes; UP000001074; Unassembled WGS sequence.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:Ensembl.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 2.30.30.190; CAP Gly-rich-like domain; 3.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR036859; CAP-Gly_dom_sf.
DR InterPro; IPR000938; CAP-Gly_domain.
DR PANTHER; PTHR18916:SF32; CAP-GLY DOMAIN-CONTAINING LINKER PROTEIN 4; 1.
DR PANTHER; PTHR18916; DYNACTIN 1-RELATED MICROTUBULE-BINDING; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF01302; CAP_GLY; 3.
DR SMART; SM00248; ANK; 3.
DR SMART; SM01052; CAP_GLY; 3.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF74924; Cap-Gly domain; 3.
DR PROSITE; PS50088; ANK_REPEAT; 1.
DR PROSITE; PS00845; CAP_GLY_1; 1.
DR PROSITE; PS50245; CAP_GLY_2; 3.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000001074}.
FT REPEAT 186..218
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 303..345
FT /note="CAP-Gly"
FT /evidence="ECO:0000259|PROSITE:PS50245"
FT DOMAIN 504..546
FT /note="CAP-Gly"
FT /evidence="ECO:0000259|PROSITE:PS50245"
FT DOMAIN 641..683
FT /note="CAP-Gly"
FT /evidence="ECO:0000259|PROSITE:PS50245"
FT REGION 413..482
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 419..434
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 449..482
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 702 AA; 75488 MW; 7F530DA8C514F6D8 CRC64;
MTIEDLPEFP LEGESLIGRY PFLFSGSDTP VTFSISAAPM PSDCEFSFFD PNDTSCQEIL
FDPKTSVSEL FAILRQWVPQ VQQNIDIIGN EILKRGCNVN DRDGLTDMTL LHYTCKSGAH
GIGDVDTAVK FATQLIDLGA DVSLRSRWTN MNALHYAAYF DVPELVRVIL KTSKPKDVDA
TCSDFNFGTA LHIAAYNLCA GTVKCLLELG ANPAFRNDKG EMPADVVPDP VEMPLEMADA
AATAKEIKQM LLDAVPLLCD VSKPVPPSSD RAAGKAVLTS AGLKLGDRVV IAGQKVGTLR
FCGTTEFASG QWAGIELDEP EGKNNGSVGK VQYFKCAPKY GIFAPLSKIS KAKDRRKNII
HSPSTKAVPL TRSQKIDVAH VTSKVNTGLM PSKRDGASES TLSLPAGEEL KTATEKDAHL
PGSISSLSSA SSLEHKQSHP RKLHARGSGK PTSSKSPSAP SRASAGLKSS ATSGANSTRP
TGELQLGDRV LVVGQRMGTI RFFGTTNFAP GQWYGIELEK PHGKNDGSVG GVQYFSCSPR
YGIFAPPSRV QRVTDSLDTL SEISSNKQNH SYPGFRRSFS TTSASSQKEI NRRNAFAKSK
TALRRSWSGS APGVEGGARL HEGSQVLLTS SNEMGTVRYV GPTDFALGIW LGLELRSAKG
RNDGAVGDTR YFTCKPNHGV LVRPSRVTYR GINGSKLVDE NC
//
