ID G1PJT7_MYOLU Unreviewed; 1134 AA.
AC G1PJT7;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=Exportin-4 {ECO:0000256|ARBA:ARBA00040444};
GN Name=XPO4 {ECO:0000313|Ensembl:ENSMLUP00000011027.2};
OS Myotis lucifugus (Little brown bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=59463 {ECO:0000313|Ensembl:ENSMLUP00000011027.2, ECO:0000313|Proteomes:UP000001074};
RN [1] {ECO:0000313|Ensembl:ENSMLUP00000011027.2, ECO:0000313|Proteomes:UP000001074}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSMLUP00000011027.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the exportin family.
CC {ECO:0000256|ARBA:ARBA00009466}.
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DR EMBL; AAPE02010063; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAPE02010064; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAPE02010065; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAPE02010066; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1PJT7; -.
DR STRING; 59463.ENSMLUP00000011027; -.
DR Ensembl; ENSMLUT00000012103.2; ENSMLUP00000011027.2; ENSMLUG00000012089.2.
DR eggNOG; KOG4541; Eukaryota.
DR GeneTree; ENSGT00940000153139; -.
DR HOGENOM; CLU_005818_0_0_1; -.
DR InParanoid; G1PJT7; -.
DR OMA; SCKSIFH; -.
DR TreeFam; TF312991; -.
DR Proteomes; UP000001074; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005049; F:nuclear export signal receptor activity; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR044189; XPO4/7-like.
DR PANTHER; PTHR12596; EXPORTIN 4,7-RELATED; 1.
DR PANTHER; PTHR12596:SF1; EXPORTIN-4; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001074}.
SQ SEQUENCE 1134 AA; 128150 MW; C2CF830225EAA06A CRC64;
VKAPPSMVNN EQRQHAEHIF LSFRKSKSPF AVCKHILETS KVDYVLFQAA TAIMEAVVRE
WILLEKGSIE SLRTFLLTYV LQRPNLQKYV REQILLAVAV IVKRGSLDKS IDCKSIFHEV
SQLISSGNPT VQTLACSILT ALLSEFSSSS KTSNIGLSME FHGNCKRVFQ EEDLRQIFVL
TVEVLQEFSR RENLSAQMSS VFQRYLSLAN QVLSWNFLPP KLGRHYIAMF ESSQNVLLKP
TESWREALLD SRVMELFFTV HRKIREDSDM AQDSLQCLAQ LASLHGPVFP DEGAQVDYLA
HFIEGLLSTI NGIEIEDSEA VGISSIISNL ITVFPRNVLT AIPSELFSSF VNCLTHLTCS
FGRSAALEEV LDKDDMVYME AYDKLLESWL TLVQDDKHFH KGFFTQHAVQ VFNSYIQCHL
AAPDGTRNLT ANGVTSREEE EISELQEDDR DQFSDQLASV GMLGRVAAEH CIPLLTSLLE
ERVTRLHGQL QRHQQQLLAS PGSSTIDSKI LDELYEDIHW LILVTAEGYL LADDTQGETP
LIPPEIMEYS IKHSSEVDIN TTLQILGSPG EKASSIPGYN RTDSVISHRL LSAVLRVSEV
ESRAIRADLT DLLSPQMGKD IVWFLKRWAK TYLLVDEKLY DQISLPFSTA FGADTEGSQW
IIGYLLQKVI SNLSVWSSEQ DLASDTVQLL VTLVERRERA NLVIQCENWW NLAKQFATRS
PPLNFLSSPV QRTLMKALVL GGFAQMDTET KQQYWTEVLQ PLQQRFLRVI NQENFQQMCQ
QEEVKQEITA TLEALCGIAE ATQIDNVAIL FNFLMDFLTN CIGLMEVYKN TPETVNLIIE
VFVEVAHKQI CYLGESKAMN LYEACLTLLQ VYSKNNLGRQ RVDVTAEEEQ YQDLLLIMEL
LTNLLSKEFI DFSDTDEVFR GHEPGQAASR SVSAADVVLY GVNLILPLMS QDLLKFPTLC
NQYYKLITFI CEIFPEKIPQ LPEDLFKSLM CSLELGMTSM SSEVCQLCLE ALTPLAEQCA
KAQDTDSPLF LATRHFLKLV FDMLVLQKHN TEMTTAAGEA FYTLVCLHQA EYSELVETLL
SSQQDPVIYQ RLADAFNKLT ASSTPPTLDR KQKMAFLKSL EEFMANVGGL LCVK
//
