ID G1PLF4_MYOLU Unreviewed; 465 AA.
AC G1PLF4;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=DNA polymerase delta subunit 3 {ECO:0000256|ARBA:ARBA00017589};
OS Myotis lucifugus (Little brown bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=59463 {ECO:0000313|Ensembl:ENSMLUP00000011686.2, ECO:0000313|Proteomes:UP000001074};
RN [1] {ECO:0000313|Ensembl:ENSMLUP00000011686.2, ECO:0000313|Proteomes:UP000001074}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSMLUP00000011686.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; AAPE02040795; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAPE02040796; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1PLF4; -.
DR STRING; 59463.ENSMLUP00000011686; -.
DR Ensembl; ENSMLUT00000012847.2; ENSMLUP00000011686.2; ENSMLUG00000012843.2.
DR eggNOG; ENOG502QPSW; Eukaryota.
DR GeneTree; ENSGT00940000163239; -.
DR HOGENOM; CLU_047571_0_0_1; -.
DR InParanoid; G1PLF4; -.
DR OMA; QMLYDFH; -.
DR TreeFam; TF103006; -.
DR Proteomes; UP000001074; Unassembled WGS sequence.
DR GO; GO:0043625; C:delta DNA polymerase complex; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR Gene3D; 3.90.1030.20; DNA polymerase delta, p66 (Cdc27) subunit, wHTH domain; 1.
DR InterPro; IPR019038; POLD3.
DR InterPro; IPR041913; POLD3_sf.
DR PANTHER; PTHR17598; DNA POLYMERASE DELTA SUBUNIT 3; 1.
DR PANTHER; PTHR17598:SF13; DNA POLYMERASE DELTA SUBUNIT 3; 1.
DR Pfam; PF09507; CDC27; 1.
PE 4: Predicted;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000001074}.
FT REGION 151..187
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 199..228
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 273..387
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 405..465
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 284..331
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 344..365
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 405..421
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 429..445
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 465 AA; 51364 MW; 8F5EFC22141D1E46 CRC64;
MADQLYLENI DEFVTDQNKI VTYKWLSYTL GVHVNQAKQM LYDYVERKRK ENSGAQLHVT
YLVSGSLVQN GHLCHKVAVV REDKLEAVKS KLAVTASVHV YSIQKAMLKD SGPLFNTDYD
ILKSNLQNCS KFSAIQCAAA VPRASAEISS SEKFDQSNLQ VSSETQANSE LTTNGHGPPT
SKQISHQPKG IMGMFASKAA SKNQDTNKET KTEAKEVTNA SSVGNKAPGK GNVMSNFFGK
AAMNKLKVNL DSEQEVKEEK VVEQPLLSVT EPKLAAPAGL KKPSKKAEPI KMQQKDGHRG
KRVEFSDDET KETVNMKKKR RRLKLPESDS SEDEVLPDSP GVYEAESPSP PPPASPPPEP
VTKTEPEPPS VKSLSGENKR KRKRVMKSKT FVDEEGCIVT EKVFESESCT DSEEELKMKT
SSIHRPPAMT VKKEPKEERK GPKKGTAALG KANRQVSITG FFQRK
//
