ID G1PMI1_MYOLU Unreviewed; 154 AA.
AC G1PMI1;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE RecName: Full=Myoglobin {ECO:0000256|RuleBase:RU251113};
GN Name=MB {ECO:0000313|Ensembl:ENSMLUP00000012110.2};
OS Myotis lucifugus (Little brown bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=59463 {ECO:0000313|Ensembl:ENSMLUP00000012110.2, ECO:0000313|Proteomes:UP000001074};
RN [1] {ECO:0000313|Ensembl:ENSMLUP00000012110.2, ECO:0000313|Proteomes:UP000001074}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSMLUP00000012110.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Serves as a reserve supply of oxygen and facilitates the
CC movement of oxygen within muscles. {ECO:0000256|ARBA:ARBA00002755,
CC ECO:0000256|RuleBase:RU251113}.
CC -!- SIMILARITY: Belongs to the globin family.
CC {ECO:0000256|ARBA:ARBA00008705, ECO:0000256|PROSITE-ProRule:PRU00238,
CC ECO:0000256|RuleBase:RU000356}.
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DR EMBL; AAPE02024922; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006092768.1; XM_006092706.2.
DR AlphaFoldDB; G1PMI1; -.
DR STRING; 59463.ENSMLUP00000012110; -.
DR Ensembl; ENSMLUT00000013311.2; ENSMLUP00000012110.2; ENSMLUG00000013313.2.
DR GeneID; 102421481; -.
DR KEGG; mlf:102421481; -.
DR CTD; 4151; -.
DR eggNOG; KOG3378; Eukaryota.
DR GeneTree; ENSGT00940000160809; -.
DR HOGENOM; CLU_003827_18_0_1; -.
DR InParanoid; G1PMI1; -.
DR OMA; MRLFQDH; -.
DR OrthoDB; 4233999at2759; -.
DR TreeFam; TF332967; -.
DR Proteomes; UP000001074; Unassembled WGS sequence.
DR GO; GO:0016528; C:sarcoplasm; IEA:Ensembl.
DR GO; GO:0020037; F:heme binding; IEA:UniProtKB-UniRule.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0098809; F:nitrite reductase activity; IEA:Ensembl.
DR GO; GO:0019825; F:oxygen binding; IEA:UniProtKB-UniRule.
DR GO; GO:0005344; F:oxygen carrier activity; IEA:UniProtKB-UniRule.
DR GO; GO:0004601; F:peroxidase activity; IEA:Ensembl.
DR GO; GO:0019430; P:removal of superoxide radicals; IEA:Ensembl.
DR Gene3D; 6.10.140.2100; -; 1.
DR Gene3D; 6.10.140.2110; -; 1.
DR InterPro; IPR000971; Globin.
DR InterPro; IPR009050; Globin-like_sf.
DR InterPro; IPR002335; Myoglobin.
DR PANTHER; PTHR47132; MYOGLOBIN; 1.
DR PANTHER; PTHR47132:SF1; MYOGLOBIN; 1.
DR Pfam; PF00042; Globin; 1.
DR PRINTS; PR00613; MYOGLOBIN.
DR SUPFAM; SSF46458; Globin-like; 1.
DR PROSITE; PS01033; GLOBIN; 1.
PE 3: Inferred from homology;
KW Heme {ECO:0000256|ARBA:ARBA00022617, ECO:0000256|RuleBase:RU000356};
KW Iron {ECO:0000256|RuleBase:RU251113};
KW Metal-binding {ECO:0000256|RuleBase:RU251113};
KW Muscle protein {ECO:0000256|ARBA:ARBA00023179,
KW ECO:0000256|RuleBase:RU251113};
KW Oxygen transport {ECO:0000256|ARBA:ARBA00022621,
KW ECO:0000256|RuleBase:RU000356};
KW Reference proteome {ECO:0000313|Proteomes:UP000001074};
KW Transport {ECO:0000256|RuleBase:RU000356}.
FT DOMAIN 3..148
FT /note="Globin family profile"
FT /evidence="ECO:0000259|PROSITE:PS01033"
SQ SEQUENCE 154 AA; 16918 MW; 961B76102CDB85C9 CRC64;
MGLSDAEWQL VLNAWGKVEA DIPGHGQAVL ISLFKGHPET QDKFEKLKNL KSEDEMKASE
DLKKQGATVL TALGGILKKK GQHEAELKPL AESHATKHKV PVEYLEFISN SIIEVLKSKL
GGDFGDDAKG AMKKALELFR NDMAAKYKEL GFQG
//
