ID G1PMP7_MYOLU Unreviewed; 255 AA.
AC G1PMP7;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=Spindle and kinetochore-associated protein 1 {ECO:0000256|ARBA:ARBA00017140};
GN Name=SKA1 {ECO:0000313|Ensembl:ENSMLUP00000012181.2};
OS Myotis lucifugus (Little brown bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=59463 {ECO:0000313|Ensembl:ENSMLUP00000012181.2, ECO:0000313|Proteomes:UP000001074};
RN [1] {ECO:0000313|Ensembl:ENSMLUP00000012181.2, ECO:0000313|Proteomes:UP000001074}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSMLUP00000012181.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the SKA1 family.
CC {ECO:0000256|ARBA:ARBA00006836}.
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DR EMBL; AAPE02009041; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAPE02009042; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1PMP7; -.
DR STRING; 59463.ENSMLUP00000012181; -.
DR Ensembl; ENSMLUT00000013391.2; ENSMLUP00000012181.2; ENSMLUG00000013388.2.
DR eggNOG; KOG4832; Eukaryota.
DR GeneTree; ENSGT00390000011654; -.
DR HOGENOM; CLU_096842_0_0_1; -.
DR InParanoid; G1PMP7; -.
DR OMA; PTGMRED; -.
DR TreeFam; TF324442; -.
DR Proteomes; UP000001074; Unassembled WGS sequence.
DR GO; GO:0034451; C:centriolar satellite; IEA:Ensembl.
DR GO; GO:0045171; C:intercellular bridge; IEA:Ensembl.
DR GO; GO:0000940; C:outer kinetochore; IEA:Ensembl.
DR GO; GO:0005876; C:spindle microtubule; IEA:Ensembl.
DR GO; GO:0008017; F:microtubule binding; IEA:Ensembl.
DR GO; GO:0051315; P:attachment of mitotic spindle microtubules to kinetochore; IEA:Ensembl.
DR GO; GO:0051301; P:cell division; IEA:Ensembl.
DR GO; GO:0031110; P:regulation of microtubule polymerization or depolymerization; IEA:Ensembl.
DR CDD; cd12958; SKA1_N; 1.
DR Gene3D; 6.10.250.1370; -; 1.
DR Gene3D; 1.10.10.1890; Ska1 microtubule binding domain-like; 1.
DR InterPro; IPR009829; SKA1.
DR InterPro; IPR042031; SKA1-MBD.
DR PANTHER; PTHR28573; SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 1; 1.
DR PANTHER; PTHR28573:SF1; SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 1; 1.
DR Pfam; PF07160; SKA1; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000001074}.
FT COILED 53..87
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 255 AA; 29385 MW; A6CAB52415367020 CRC64;
FLTLCLDQIC FHISEKIGNI KKSLSLRNCG QEPNSKTILN KIGDEILVIN ELLNKLELEI
QFQEQTTDSL KELCASLEED YKDVEHLKEN IPPHLPQVTV TQNSVNVSDL DSEEPVKVEE
PGVTKKPSKE QRNIKEMPFI TSEEFNGIPA YMKSRLTYCQ INDVIKEINK AVVSKYKILH
QPKKSMSSVA RNLYHRFIDE ETKDTKGHYF VVEADIKEFT ALKVDKRFHV ILNILRHCRR
LSEVRGGGLT RYVIT
//
