ID G1PMV9_MYOLU Unreviewed; 843 AA.
AC G1PMV9;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Tetratricopeptide repeat domain 16 {ECO:0000313|Ensembl:ENSMLUP00000012250.2};
GN Name=TTC16 {ECO:0000313|Ensembl:ENSMLUP00000012250.2};
OS Myotis lucifugus (Little brown bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=59463 {ECO:0000313|Ensembl:ENSMLUP00000012250.2, ECO:0000313|Proteomes:UP000001074};
RN [1] {ECO:0000313|Ensembl:ENSMLUP00000012250.2, ECO:0000313|Proteomes:UP000001074}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSMLUP00000012250.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAPE02044252; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1PMV9; -.
DR STRING; 59463.ENSMLUP00000012250; -.
DR Ensembl; ENSMLUT00000013464.2; ENSMLUP00000012250.2; ENSMLUG00000013457.2.
DR eggNOG; KOG1124; Eukaryota.
DR GeneTree; ENSGT00390000004550; -.
DR HOGENOM; CLU_017316_1_0_1; -.
DR InParanoid; G1PMV9; -.
DR OMA; CQEYRST; -.
DR TreeFam; TF350096; -.
DR Proteomes; UP000001074; Unassembled WGS sequence.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 4.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR45153; TETRATRICOPEPTIDE REPEAT PROTEIN 16; 1.
DR PANTHER; PTHR45153:SF1; TETRATRICOPEPTIDE REPEAT PROTEIN 16; 1.
DR Pfam; PF12895; ANAPC3; 1.
DR Pfam; PF13432; TPR_16; 1.
DR Pfam; PF13181; TPR_8; 1.
DR SMART; SM00028; TPR; 9.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 5.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001074};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT REPEAT 64..97
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 98..131
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 139..172
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 288..321
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 368..401
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 552..821
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..23
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 552..589
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 590..645
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 658..774
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 802..818
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 843 AA; 95786 MW; AE89E1F339D2FF7A CRC64;
AAELEQKSGK GEAGLEREDS PEPKPWATPL PKETIKRIFG TSQAFRGFDE IKPTLSEITV
PLKVREYYHR GHWCLEREDW ETAVVFFSRA IHLDPQLVEF YALRAEAYIQ LCDYSSAVQN
LRRAHSFQPE NTQFLKRLTL VLYLQGQCLF EQCAFADALN VFSQAFELQP KKPSFRYRCM
ACLLALRRYQ DCLSLVTKEV EYGTTNADIY ILRARLYNSM GKPHLCYQDL HSALVLDPKH
TQAKVLLKMM VEKSQKSFRD ARILAVQGKL QHAVQCVNSA IDNNPLDPSF FLFRGTMYRR
LRDFDAAVED FLKALDMMSE HQEDMVRQAQ RQLLLAYNDF ALHCYMQGAY QEGVLLLNKV
LKDEQGEKGL YINRGDCFFQ LGYLNFAEAD YQEALTLSPS DEGANLRMSL LQEKMGCCEH
KSKQFQKAES HFTLAIQHNP QMAQYYLHRA RSRQFIQNIF GARQDVATAL ILDPKQPKLL
SLITILFPGM SMEEVLGSHV GLLAKMQLSR VIESRRKDNI SQGIMGKLYK QELERQKART
LQLSWKEQQV LRETKPQKLD SKSRIPQEGP EHPEEAMDAE KKEKPEQSLS DSYPDQTSSV
SMLGFRTLSV SETETSTTCQ EYRSTSATPV PLTSDSSLLR TQSSDLGNDR KTEVTRSQSQ
KPSKTEATQG PRQRPTKTEA TQGPRQKPSK TEATQGPRQK PSKTEATQGP RQKPSKTEAT
QGPRQRPTKT EATQGPRQKP SKTEATQGPR QKPSKTEATQ GPRQRPTKTE ATQGPRRSPI
KAEATRGRTR GLIRSSSKTK SDDDSSWSPS NTEDAQGESQ WLVMAKVLEN WNQSPSPESS
KTD
//
