ID G1PNM5_MYOLU Unreviewed; 343 AA.
AC G1PNM5;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Leucine rich repeat containing 23 {ECO:0000313|Ensembl:ENSMLUP00000012558.2};
GN Name=LRRC23 {ECO:0000313|Ensembl:ENSMLUP00000012558.2};
OS Myotis lucifugus (Little brown bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=59463 {ECO:0000313|Ensembl:ENSMLUP00000012558.2, ECO:0000313|Proteomes:UP000001074};
RN [1] {ECO:0000313|Ensembl:ENSMLUP00000012558.2, ECO:0000313|Proteomes:UP000001074}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSMLUP00000012558.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAPE02007013; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006084237.1; XM_006084175.2.
DR RefSeq; XP_014307109.1; XM_014451623.1.
DR RefSeq; XP_014307110.1; XM_014451624.1.
DR RefSeq; XP_014307111.1; XM_014451625.1.
DR AlphaFoldDB; G1PNM5; -.
DR STRING; 59463.ENSMLUP00000012558; -.
DR Ensembl; ENSMLUT00000013801.2; ENSMLUP00000012558.2; ENSMLUG00000013800.2.
DR eggNOG; KOG0531; Eukaryota.
DR GeneTree; ENSGT00940000159748; -.
DR HOGENOM; CLU_056804_1_1_1; -.
DR InParanoid; G1PNM5; -.
DR OMA; NPCTDES; -.
DR OrthoDB; 1330382at2759; -.
DR TreeFam; TF329158; -.
DR Proteomes; UP000001074; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR15454:SF47; LEUCINE-RICH REPEAT-CONTAINING PROTEIN 23; 1.
DR PANTHER; PTHR15454; NISCHARIN RELATED; 1.
DR Pfam; PF14580; LRR_9; 1.
DR SMART; SM00365; LRR_SD22; 4.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 4.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001074};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REGION 1..46
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 306..343
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..44
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 306..328
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 329..343
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 343 AA; 39663 MW; E9B93642E1F64FE8 CRC64;
MSDEDDLEDF EPDQDDLERE DDEKDTEDWE DDRKEEEDLS EEWMPTPLTE DMMKEGLSLL
CKTGNGLAHA YVKLEVKERE LTDIQLLRSY IHLRYVDISE NHLTDVSALN HLTHLLWLKA
DGNRLRSAQL NELPYLQIAS FAYNQIADTE GISHPRLGIL NLKGNHIRLV TGMDPEKLIS
LHTLELRGNQ LESTVGINVP TLKNLFLAQN MLKKVEGLEH LKNLTTLHLR DNQIDTLSGF
SEGMKSLQYL NLRGNMVSNL QELAKLQNLP KLRALVLLDN PCTDESDYRQ EALVHIPQLE
RLDKEFFEEE DRAEANEIRQ RMKEEQEQEQ DAETEQDIGP DQP
//
