ID G1PQ07_MYOLU Unreviewed; 220 AA.
AC G1PQ07;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=RPA interacting protein {ECO:0000313|Ensembl:ENSMLUP00000013124.2};
GN Name=RPAIN {ECO:0000313|Ensembl:ENSMLUP00000013124.2};
OS Myotis lucifugus (Little brown bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=59463 {ECO:0000313|Ensembl:ENSMLUP00000013124.2, ECO:0000313|Proteomes:UP000001074};
RN [1] {ECO:0000313|Ensembl:ENSMLUP00000013124.2, ECO:0000313|Proteomes:UP000001074}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSMLUP00000013124.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AAPE02045494; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1PQ07; -.
DR STRING; 59463.ENSMLUP00000013124; -.
DR Ensembl; ENSMLUT00000014432.2; ENSMLUP00000013124.2; ENSMLUG00000014428.2.
DR eggNOG; ENOG502R0QT; Eukaryota.
DR GeneTree; ENSGT00390000006416; -.
DR HOGENOM; CLU_086690_0_0_1; -.
DR InParanoid; G1PQ07; -.
DR OMA; HGVAQMF; -.
DR TreeFam; TF326215; -.
DR Proteomes; UP000001074; Unassembled WGS sequence.
DR GO; GO:0001650; C:fibrillar center; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006606; P:protein import into nucleus; IEA:Ensembl.
DR InterPro; IPR028156; RIP.
DR InterPro; IPR028159; RPA_interact_C_dom.
DR InterPro; IPR028155; RPA_interact_central.
DR InterPro; IPR028158; RPA_interact_N_dom.
DR PANTHER; PTHR31742:SF1; RPA-INTERACTING PROTEIN; 1.
DR PANTHER; PTHR31742; RPA-INTERACTING PROTEIN RPAIN; 1.
DR Pfam; PF14768; RPA_interact_C; 1.
DR Pfam; PF14767; RPA_interact_M; 1.
DR Pfam; PF14766; RPA_interact_N; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000001074};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 8..47
FT /note="RPA-interacting protein N-terminal"
FT /evidence="ECO:0000259|Pfam:PF14766"
FT DOMAIN 79..125
FT /note="RPA-interacting protein central"
FT /evidence="ECO:0000259|Pfam:PF14767"
FT DOMAIN 137..215
FT /note="RPA-interacting protein C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14768"
SQ SEQUENCE 220 AA; 25150 MW; 227B97243C2EDCD6 CRC64;
MAEQSGSPHR SMYKLVGSPP WKETFRQDAW ERMRNSRDRL LDKYRQAGGN VPGRAQSTLL
AQELMEEEWN AWHSMESCPE AQVRLWEEPM DLAELEEIQQ ELIDQEQSII NEYEKSLQFD
EQCLSIILAE WEANSLICPV CIKYNLRITS GVVMCQCGLY IPSHSPELTE QKLRACLEDS
MNEHSAHCPH TPQFSVTEGT GRKSSLLMSC LACDARAAII
//
