ID G1PTF6_MYOLU Unreviewed; 1462 AA.
AC G1PTF6;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Calmodulin binding transcription activator 1 {ECO:0000313|Ensembl:ENSMLUP00000014507.2};
GN Name=CAMTA1 {ECO:0000313|Ensembl:ENSMLUP00000014507.2};
OS Myotis lucifugus (Little brown bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=59463 {ECO:0000313|Ensembl:ENSMLUP00000014507.2, ECO:0000313|Proteomes:UP000001074};
RN [1] {ECO:0000313|Ensembl:ENSMLUP00000014507.2, ECO:0000313|Proteomes:UP000001074}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSMLUP00000014507.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAPE02046000; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAPE02046001; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAPE02046002; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAPE02046003; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAPE02046004; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAPE02046005; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAPE02046006; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAPE02046007; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 59463.ENSMLUP00000014507; -.
DR Ensembl; ENSMLUT00000015927.2; ENSMLUP00000014507.2; ENSMLUG00000015907.2.
DR eggNOG; KOG0520; Eukaryota.
DR GeneTree; ENSGT00940000155203; -.
DR HOGENOM; CLU_003170_1_0_1; -.
DR InParanoid; G1PTF6; -.
DR OMA; AMAYMHV; -.
DR TreeFam; TF323452; -.
DR Proteomes; UP000001074; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005730; C:nucleolus; IEA:Ensembl.
DR GO; GO:0070886; P:positive regulation of calcineurin-NFAT signaling cascade; IEA:Ensembl.
DR GO; GO:0035307; P:positive regulation of protein dephosphorylation; IEA:Ensembl.
DR Gene3D; 1.20.5.190; -; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR PANTHER; PTHR23335:SF11; CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR 1; 1.
DR PANTHER; PTHR23335; CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR CAMTA; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF00612; IQ; 1.
DR Pfam; PF01833; TIG; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 1.
DR PROSITE; PS50096; IQ; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Reference proteome {ECO:0000313|Proteomes:UP000001074};
KW Transcription {ECO:0000256|ARBA:ARBA00023163}.
FT DOMAIN 655..733
FT /note="IPT/TIG"
FT /evidence="ECO:0000259|Pfam:PF01833"
FT REPEAT 845..867
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 70..158
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 378..401
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 771..804
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 951..972
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 996..1028
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1046..1099
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1243..1268
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 88..114
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 120..153
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 378..399
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 777..804
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1003..1017
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1046..1066
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1243..1259
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1462 AA; 157509 MW; 6B801DC777E16EEA CRC64;
LSPPVHGIKW TCSNGNSSSG FSVEQLVQQI LDSHQTKPQP RTHNCLCAGG LGAGSSVHHK
CNSAKHRIIS PKVEPRTGGY GGHAEVQHND VSEGKQEHSH GKGSSREKRN GKVAKPVLLH
QSSTEVSSTN QVEVPDTTQS SPVSISSGLN SDPDMADSPV VTGVSSMAVA SVMGSLSQSA
TVFMSEVTNE AVYTMSPTAG PNHHLLSPDA SQGLVLAMSS DGHKFAFPTP GGSDSLSMLP
SNVSEELVLS TTLDSGRKIP ETTMNFDPDC FLNNPKQGQT YGGGGLKAEM VSAGVRHSPP
VERAFSFTTV LAKEIKTEDT SFEQQMAKEA YSSSAAAAGS LSLSAGPSLL PSGGGLSPST
TLEQMDFSAI DSNKDYASSF SQTGHSPHIH QTPSPSFFLQ DASKPLPLEQ SAHSSLSDSG
GTFVMPTVKT EASSQTSSCS GHVETRIEST SSLHLMQFQA NFQAMGAEGE VTMETSQVAE
GGEGLIKSGE LQACGSEHYL QPETPGVIRS TGGVPLLPGN VVQGLYPVAQ PGLGNASNME
LSLDHFDISF SNQFSDLIND FISVEGGSGT IYGHQLVSGD GAALSQSEDG ARAPFAQAEM
CIPCCSPQQG SLQLSGAEGG AGTMAYMHVA EVVSAASARG IWGCCSRADA CSMGTDYSPE
WSYSEGGVKV LITGPWQEAS NNYSCLFDQI SVPASLIQPG VLRCYCPAHD TGLVTLQVAF
NNQIISNSVV FEYKARALPT LPSSQHDWLS LDDNQFRMSI LERLEQMERR MAEMTGSQQH
KPGSAGGGSG GGASSGNGGS QAQCAPGPGT LGSCFESRVV VVCEKMMSRA CWAKSKHLIH
SKTFRGMTLL HLAAAQGYAT LIQTLIKWRT KHADSIDLEL EVDPLNVDHF SCTPLMWACA
LGHLEAAVVL YKWDRRAISI PDSLGRLPLG IARSRGHVKL AECLEHLQRG EQAPLGQSPR
IHCPPSEEPH ADGWMAQWHS EAIASPEIPK GVTVIASTNP ELRRPRSEPS NYYSSESHKD
YPAPKKHKLN PESFQARQEE LLSTALSLEQ PRIRKQSPSS KQAAPETLSP REGARACSRA
PSPPSPEPAG LRAAAAQPQP VVRWSPKDLS IGVSTVQVTG SPKGTSVGKE AAPAQVPPRE
PMSVLMMASR EVAHTEMGPY RDSAEAEDGS QPMDDIQVNM MALAEHIIEA TPERIKQNFV
PTEAPALERT EAATVSSTMS WLASYLADVD HLPHAAQLRS AYSEPLTPSS NTSLSPGGSP
ASDMAFEKPS LPSAADWSEF LSASTSEKVE NEFAQLTLSD HEQRELYEAA RLVQTAFRKY
KGRPLREQQE VAAAVIQRCY RKYKQLTWIV LKYALYKKMT QAAILIQSKF RSYYEQKKFQ
QSRRAAVLIQ KFYRSYRRCG QRRPARRTAV IVQQRLRSSL LTKKQDQAAR KIMRFLRRCR
HSPLADHRLY KRVSELPAGP FT
//
